[
  {
    "nct_id": "NCT05725655",
    "title": "Hot Water Immersion After Myocardial Infarction",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Cardiac Disease",
      "Cardiac Rehabilitation"
    ],
    "interventions": [
      {
        "name": "Thermotherapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Örebro University hospital, Örebro, Sweden"
    ],
    "start_date": "2023-10-26",
    "completion_date": "2027-07-30",
    "last_update": "2026-08-12",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05725655"
  },
  {
    "nct_id": "NCT07761741",
    "title": "Title of the Research: Effect of Manual Lymphatic Drainage Massage Combined With Therapeutic Exercises On Lower Limbs Edema During Late Pregnancy",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Pregnancy Complication"
    ],
    "interventions": [
      {
        "name": "manual lymphatic drainage massage technique with specific therapeutic exercise",
        "type": "OTHER"
      },
      {
        "name": "Control group",
        "type": "OTHER"
      }
    ],
    "locations": [],
    "start_date": "2026-08-08",
    "completion_date": "2026-10-15",
    "last_update": "2026-08-08",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07761741"
  },
  {
    "nct_id": "NCT07744269",
    "title": "CRPS-Hand: Contrast + Compression vs Whirlpool",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 50,
    "conditions": [
      "Complex Regional Pain Syndrome I (CRPS I)"
    ],
    "interventions": [
      {
        "name": "Combined Contrast Therapy with Intermittent Compression",
        "type": "DEVICE"
      },
      {
        "name": "Whirlpool Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Etlik City Hospital, Department of Physical Medicine and Rehabilitation, Ankara, Yenimahalle, Turkey (Türkiye)"
    ],
    "start_date": "2026-05-01",
    "completion_date": "2027-07-30",
    "last_update": "2026-08-01",
    "topics": [
      "contrast-therapy"
    ],
    "topic_names": [
      "Contrast Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07744269"
  },
  {
    "nct_id": "NCT07123285",
    "title": "Effect of Photobiomodulation on Healing of Venous Leg Ulcers",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 102,
    "conditions": [
      "Venous Leg Ulcer (VLU)",
      "Venous Hypertension Ulcers",
      "Chronic Venous Insufficiency",
      "Chronic Venous Disease"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation Therapy",
        "type": "DEVICE"
      },
      {
        "name": "Sham Photobiomodulation",
        "type": "DEVICE"
      },
      {
        "name": "Compression Therapy",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Estratégia Saúde da Família Vereador Carlos Alberto Baptistela - Maria Cristina, Lençóis Paulista, São Paulo, Brazil"
    ],
    "start_date": "2026-08",
    "completion_date": "2027-07",
    "last_update": "2026-07-28",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07123285"
  },
  {
    "nct_id": "NCT07729735",
    "title": "Physiotherapy After Breast Reduction Surgery",
    "status": "ENROLLING_BY_INVITATION",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Breast",
      "Posture",
      "Mammaplasty",
      "Sleep Quality"
    ],
    "interventions": [
      {
        "name": "Physiotherapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Istanbul Rumeli university, Istanbul, Turkey (Türkiye)"
    ],
    "start_date": "2026-07-23",
    "completion_date": "2026-08-25",
    "last_update": "2026-07-23",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07729735"
  },
  {
    "nct_id": "NCT07246980",
    "title": "Continuous Observational Monitoring Program for Allay™ Hydrogel Cap Safety and Success Study",
    "status": "RECRUITING",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 1000,
    "conditions": [
      "Peripheral Nerve Injuries"
    ],
    "interventions": [
      {
        "name": "Nerve Cap",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Orlando Health, Orlando, Florida, United States",
      "Florida Orthopedic Institute, St. Petersburg, Florida, United States",
      "Complete Foot and Ankle Care of North Texas, PA, Denton, Texas, United States"
    ],
    "start_date": "2026-05-06",
    "completion_date": "2029-05-01",
    "last_update": "2026-07-22",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07246980"
  },
  {
    "nct_id": "NCT07714720",
    "title": "Photobiomodulation for Median Nerve Neuroplasticity in Carpal Tunnel Syndrome: A Randomized Controlled Trial",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 70,
    "conditions": [
      "Carpal Tunnel Syndrome (CTS)"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation (Low-Level Laser Therapy)",
        "type": "DEVICE"
      },
      {
        "name": "Sham Photobiomodulation",
        "type": "DEVICE"
      },
      {
        "name": "Routine Physiotherapy Programme",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Lahore Hospital, Lahore, Punjab Province, Pakistan"
    ],
    "start_date": "2026-08-15",
    "completion_date": "2027-08-15",
    "last_update": "2026-07-15",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07714720"
  },
  {
    "nct_id": "NCT07710417",
    "title": "FLOAT for Healthcare PTSS",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "EARLY_PHASE1"
    ],
    "enrollment": 15,
    "conditions": [
      "Posttraumatic Stress Symptoms",
      "Burnout",
      "Burnout, Healthcare Workers",
      "First Responders",
      "PTSD",
      "Healthcare Workforce Well-Being",
      "Post-traumatic Stress Symptoms"
    ],
    "interventions": [
      {
        "name": "Floatation-REST",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Documentary",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Laureate Institute for Brain Research, Tulsa, Oklahoma, United States"
    ],
    "start_date": "2026-06-10",
    "completion_date": "2026-12",
    "last_update": "2026-07-13",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07710417"
  },
  {
    "nct_id": "NCT07694999",
    "title": "Ice Packs Versus Cold Baths Combined With Standard Exercise Therapy for Plantar Fasciitis",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Plantar Fasciitis"
    ],
    "interventions": [
      {
        "name": "Ice Pack Therapy",
        "type": "PROCEDURE"
      },
      {
        "name": "Cold Water Immersion",
        "type": "PROCEDURE"
      },
      {
        "name": "Standard Exercise Therapy",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Shahab Orthopedic and General Hospital, Peshawar, Khyber Pakhtunkhwa, Pakistan"
    ],
    "start_date": "2026-02-17",
    "completion_date": "2026-07-07",
    "last_update": "2026-07-10",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07694999"
  },
  {
    "nct_id": "NCT07699679",
    "title": "Photobiomodulation in Coronary Artery Bypass Grafting With No-Touch vs Conventional Saphenous Vein Harvesting.",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 292,
    "conditions": [
      "Coronary Artery Disease",
      "Coronary Artery Bypass Graft (CABG)",
      "Surgical Wound Healing"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation Therapy",
        "type": "DEVICE"
      },
      {
        "name": "Placebo Laser",
        "type": "DEVICE"
      },
      {
        "name": "Conventional Saphenous Vein Harvesting",
        "type": "PROCEDURE"
      },
      {
        "name": "No-Touch Saphenous Vein Harvesting",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Hospital São Paulo, Federal University of São Paulo, São Paulo, São Paulo, Brazil"
    ],
    "start_date": "2026-08",
    "completion_date": "2028-03",
    "last_update": "2026-07-08",
    "topics": [
      "exercise-recovery",
      "photobiomodulation"
    ],
    "topic_names": [
      "Exercise Recovery",
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07699679"
  },
  {
    "nct_id": "NCT07691671",
    "title": "Impact of Various Myopia Management Strategies on Asthenopia Among Pediatric and Adolescent Populations",
    "status": "NOT_YET_RECRUITING",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 600,
    "conditions": [
      "Myopia",
      "Visual Fatigue"
    ],
    "interventions": [],
    "locations": [],
    "start_date": "2026-07-05",
    "completion_date": "2027-04-30",
    "last_update": "2026-07-02",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07691671"
  },
  {
    "nct_id": "NCT07082998",
    "title": "Comparing the Efficacy of Heated Yoga and Sauna as a Treatment for Depression",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 120,
    "conditions": [
      "Depression Disorders",
      "Depression - Major Depressive Disorder",
      "Depression Disorder",
      "Depression Chronic",
      "Depression",
      "Depression in Adults"
    ],
    "interventions": [
      {
        "name": "heated yoga",
        "type": "BEHAVIORAL"
      },
      {
        "name": "sauna",
        "type": "BEHAVIORAL"
      },
      {
        "name": "mindfulness app",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Massachusetts General Hospital, Boston, Massachusetts, United States"
    ],
    "start_date": "2025-09-12",
    "completion_date": "2027-07-31",
    "last_update": "2026-07-01",
    "topics": [
      "infrared-sauna",
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Infrared Sauna",
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07082998"
  },
  {
    "nct_id": "NCT07689019",
    "title": "Effects of Far Infrared Rays and Transcutaneous Electrical Nerve Stimulation on Short Term Prognosis of Head and Neck Cancer Patients Receiving Curative Treatment",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 102,
    "conditions": [
      "Head and Neck Cancer (H&N)"
    ],
    "interventions": [
      {
        "name": "Standard Care (in control arm)",
        "type": "OTHER"
      },
      {
        "name": "Transcutaneous Electrical Nerve Stimulation",
        "type": "DEVICE"
      },
      {
        "name": "Far-Infrared Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien City, Hualien County, Taiwan"
    ],
    "start_date": "2024-05-15",
    "completion_date": "2026-12-31",
    "last_update": "2026-06-30",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07689019"
  },
  {
    "nct_id": "NCT02427698",
    "title": "Cyrolipolysis vs Cyrolipolysis and Subcision for Cellulite",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 15,
    "conditions": [
      "Cellulite"
    ],
    "interventions": [
      {
        "name": "cyrolipolysis (CoolSculpting device)",
        "type": "PROCEDURE"
      },
      {
        "name": "subcision",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Northwestern University Feinberg School of Medicine, Department of Dermatology, Chicago, Illinois, United States"
    ],
    "start_date": "2015-08",
    "completion_date": "2028-12",
    "last_update": "2026-06-29",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02427698"
  },
  {
    "nct_id": "NCT07661485",
    "title": "Comparing Two Soft Tissues Technique on Piriformis Syndrome Patients",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 26,
    "conditions": [
      "Piriformis Syndrome",
      "Musculoskeletal Abnormalities",
      "Sciatica"
    ],
    "interventions": [
      {
        "name": "Myofascial Release",
        "type": "OTHER"
      },
      {
        "name": "Post Isometric Relaxation",
        "type": "OTHER"
      }
    ],
    "locations": [
      "The University of Faisalabad, Faisalābad, Punjab Province, Pakistan"
    ],
    "start_date": "2026-06-30",
    "completion_date": "2026-09-30",
    "last_update": "2026-06-25",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07661485"
  },
  {
    "nct_id": "NCT06040190",
    "title": "Effect of Treatments on Pain and Quality of Life in Individual With Burning Mouth Syndrome",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE4"
    ],
    "enrollment": 150,
    "conditions": [
      "Burning Mouth Syndrome"
    ],
    "interventions": [
      {
        "name": "topical placebo rinse",
        "type": "DRUG"
      },
      {
        "name": "topical clonazepam rinse",
        "type": "DRUG"
      },
      {
        "name": "oral alpha-lipoic acid capsule",
        "type": "DIETARY_SUPPLEMENT"
      },
      {
        "name": "topical phytotherapic capsaicin gel",
        "type": "OTHER"
      },
      {
        "name": "local photobiomodulation",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "Federal university of minas gerais, Belo Horizonte, Minas Gerais, Brazil"
    ],
    "start_date": "2023-11-01",
    "completion_date": "2026-07-10",
    "last_update": "2026-06-25",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06040190"
  },
  {
    "nct_id": "NCT03277638",
    "title": "Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM)",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1",
      "PHASE2"
    ],
    "enrollment": 32,
    "conditions": [
      "Glioblastoma, Adult"
    ],
    "interventions": [
      {
        "name": "Pembrolizumab at 7 days prior",
        "type": "DRUG"
      },
      {
        "name": "Pembrolizumab at 14 days post",
        "type": "DRUG"
      },
      {
        "name": "Pembrolizumab at 35 days post",
        "type": "DRUG"
      },
      {
        "name": "Laser Interstitial Thermotherapy",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States"
    ],
    "start_date": "2017-11-29",
    "completion_date": "2026-12",
    "last_update": "2026-06-25",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03277638"
  },
  {
    "nct_id": "NCT07672171",
    "title": "Far-Infrared Therapy for the Effect of Alzheimer Disease Dementia",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Dementia",
      "Alzheimer Disease"
    ],
    "interventions": [
      {
        "name": "Yin Fu Rui De Far-Infrared Radiator",
        "type": "DEVICE"
      },
      {
        "name": "Sham Far-Infrared Radiator",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Trial-Service General Hospital, National Defense Medical University, Taipei, Taiwan"
    ],
    "start_date": "2022-10-15",
    "completion_date": "2029-10-31",
    "last_update": "2026-06-23",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07672171"
  },
  {
    "nct_id": "NCT07233148",
    "title": "Healing ALS Registry Observational Study (HAROS)",
    "status": "RECRUITING",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 1000,
    "conditions": [
      "Amyotrophic Lateral Sclerosis (ALS)",
      "Motor Neuron Disease (MND)",
      "Primary Lateral Sclerosis (PLS)"
    ],
    "interventions": [
      {
        "name": "Education about treatment options",
        "type": "OTHER"
      },
      {
        "name": "Dietary Supplements: Vitamins, Minerals, Herbs, etc.",
        "type": "DIETARY_SUPPLEMENT"
      },
      {
        "name": "Meditation, Prayer, Talk Therapy, Affirmations, Journaling, etc.",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Diet, various diets will be observed",
        "type": "OTHER"
      },
      {
        "name": "Exercise, physical therapy, occupational therapy, speech therapy, sauna, EMS, massage and other therapies",
        "type": "OTHER"
      },
      {
        "name": "ALS medications and other medications",
        "type": "DRUG"
      },
      {
        "name": "Physical and emotional support",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Virtual, Park City, Utah, United States"
    ],
    "start_date": "2026-01-26",
    "completion_date": "2036-03-31",
    "last_update": "2026-06-19",
    "topics": [
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07233148"
  },
  {
    "nct_id": "NCT07613489",
    "title": "Photobiomodulation for Diabetic Peripheral Neuropathy",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 36,
    "conditions": [
      "Diabetic Peripheral Neuropathy",
      "Diabetes Mellitus Type 2"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation Therapy",
        "type": "DEVICE"
      },
      {
        "name": "Sham Laser Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "The University of Faisalabad, Faisalābad, Punjab Province, Pakistan"
    ],
    "start_date": "2026-02-01",
    "completion_date": "2026-06-24",
    "last_update": "2026-06-18",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07613489"
  },
  {
    "nct_id": "NCT06144294",
    "title": "Whole-Body Hyperthermia for Mood and Anxiety Disorders",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 240,
    "conditions": [
      "Postpartum Depression",
      "Mood Disorders",
      "Anxiety Disorders",
      "Postpartum Anxiety"
    ],
    "interventions": [
      {
        "name": "Whole-Body Hyperthermia",
        "type": "OTHER"
      },
      {
        "name": "fMRI",
        "type": "DIAGNOSTIC_TEST"
      }
    ],
    "locations": [
      "Weill Cornell Medicine, New York, New York, United States"
    ],
    "start_date": "2028-06",
    "completion_date": "2032-12",
    "last_update": "2026-06-18",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06144294"
  },
  {
    "nct_id": "NCT06746350",
    "title": "Feasibility of Integrating Thermotherapy for Treatment of Cutaneous Leishmaniasis in Primary Health Care Setup",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 103,
    "conditions": [
      "Cutaneous Leishmaniasis"
    ],
    "interventions": [
      {
        "name": "Thermotherapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "CDT-Africa, Addis Ababa, Ethiopia"
    ],
    "start_date": "2025-04-24",
    "completion_date": "2027-05-25",
    "last_update": "2026-06-09",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06746350"
  },
  {
    "nct_id": "NCT07641725",
    "title": "Comparison of the Efficacy of Clobetasol Propionate 0.05% Mouthwash, Photobiomodulation, and Their Combination in Managing of Oral Lesions in Patient With Pemphigus Vulgaris.",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Oral Lesions in Patients With Pemphigus Vulgaris"
    ],
    "interventions": [
      {
        "name": "Clobetasol propionate 0.05% Mouthwash",
        "type": "DRUG"
      },
      {
        "name": "diode laser for photobiomodulation",
        "type": "DEVICE"
      },
      {
        "name": "clobetasol propionate 0.05% mouthwash + photobiomodulation",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Department of Oral Medicine, Faculty of Dental medicine, Damascus, Syria"
    ],
    "start_date": "2025-11-01",
    "completion_date": "2026-12-01",
    "last_update": "2026-06-08",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07641725"
  },
  {
    "nct_id": "NCT07566260",
    "title": "Stress and Menstrual Health",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 600,
    "conditions": [
      "Menstrual Dysfunction"
    ],
    "interventions": [
      {
        "name": "Heat stress",
        "type": "OTHER"
      },
      {
        "name": "Sleep stress",
        "type": "OTHER"
      },
      {
        "name": "Exercise stress",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Duke University, Durham, North Carolina, United States"
    ],
    "start_date": "2026-05-28",
    "completion_date": "2029-08",
    "last_update": "2026-06-04",
    "topics": [
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07566260"
  },
  {
    "nct_id": "NCT07603531",
    "title": "Assessment of the Efficacy of the Dynamic Decongestive System in the Maintenance Phase of Lower Limb Lymphedema",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 98,
    "conditions": [
      "Lymphedema Lower Extremity"
    ],
    "interventions": [
      {
        "name": "Control group: Currently available compression devices",
        "type": "DEVICE"
      },
      {
        "name": "DDS group: Dynamic compression device (DDS)",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "CHU Montpellier - Saint Eloi, Montpellier, France",
      "CHU Toulouse - Rangueil, Toulouse, France",
      "Lympho-Opt Fachklinik fur Lymphologie, Pommelsbrunn, Bavaria, Germany"
    ],
    "start_date": "2026-07-01",
    "completion_date": "2027-09-30",
    "last_update": "2026-05-27",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07603531"
  },
  {
    "nct_id": "NCT07588243",
    "title": "A Clinical Study to Evaluate the Efficacy and Safety of Ultra in Promoting Hair Regrowth",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 44,
    "conditions": [
      "Androgenic Alopecia"
    ],
    "interventions": [
      {
        "name": "Low Level Laser Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Dy Dermatology, Glenview, Illinois, United States",
      "Cynosure Lutronic, Westford, Massachusetts, United States"
    ],
    "start_date": "2026-02-19",
    "completion_date": "2026-12",
    "last_update": "2026-05-22",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07588243"
  },
  {
    "nct_id": "NCT07422623",
    "title": "Hallux Valgus Correction Surgery Recovery Using Semiconductor Embedded Therapeutic Sleeves",
    "status": "ENROLLING_BY_INVITATION",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 115,
    "conditions": [
      "Hallux Valgus Deformity"
    ],
    "interventions": [
      {
        "name": "Semiconductor embedded ankle sleeve and sock",
        "type": "DEVICE"
      },
      {
        "name": "Placebo ankle sleeve and sock",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Foot and Ankle Center of Iowa, Ankeny, Iowa, United States"
    ],
    "start_date": "2026-03-01",
    "completion_date": "2027-01-01",
    "last_update": "2026-05-20",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07422623"
  },
  {
    "nct_id": "NCT07603154",
    "title": "Peng's \"Fenjin Tuina\" for Superior Cluneal Nerve Entrapment Syndrome: A Prospective, Randomized, Single-center Trial",
    "status": "ENROLLING_BY_INVITATION",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 70,
    "conditions": [
      "SCNES",
      "Superior Cluneal Nerve Entrapment Syndrome"
    ],
    "interventions": [
      {
        "name": "Peng's \"Fenjin Tuina\"",
        "type": "OTHER"
      },
      {
        "name": "conventional massage therapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, Guangdong, China"
    ],
    "start_date": "2026-04-23",
    "completion_date": "2027-04-23",
    "last_update": "2026-05-19",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07603154"
  },
  {
    "nct_id": "NCT07526012",
    "title": "Comparative Effects Of Post Isometric Relaxation Versus Active Isolated Stretch In Patients With Piriformis Syndrome",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Piriformis Syndrome",
      "Low Back Pain",
      "Hip Joint"
    ],
    "interventions": [
      {
        "name": "Post Isometric Relaxation",
        "type": "PROCEDURE"
      },
      {
        "name": "Active Isolated Stretching",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Foundation University College of Physical Therapy, Islamabad, Punjab Province, Pakistan"
    ],
    "start_date": "2026-05-20",
    "completion_date": "2026-07-15",
    "last_update": "2026-05-18",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07526012"
  },
  {
    "nct_id": "NCT07201935",
    "title": "Thermodynamic Exposure and Sleep in Military Cadets",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 45,
    "conditions": [
      "Cold-water Immersion",
      "High Heat Sauna",
      "Combination of Cold-water Immersion and High Heat Sauna"
    ],
    "interventions": [
      {
        "name": "Cold Water Immersion",
        "type": "BEHAVIORAL"
      },
      {
        "name": "High Heat Sauna",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "The Citadel Military College, Charleston, South Carolina, United States"
    ],
    "start_date": "2026-07",
    "completion_date": "2027-05",
    "last_update": "2026-05-15",
    "topics": [
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07201935"
  },
  {
    "nct_id": "NCT07598513",
    "title": "Comparative Effects of Perturbation-Based Balance Training on Firm Surface and Rolling Board for Diabetic Neuropathy Patients",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 42,
    "conditions": [
      "Balance Impairment",
      "Diabetic Neuropathy"
    ],
    "interventions": [
      {
        "name": "Group A (Perturbation Based Training on Firm Surface)",
        "type": "OTHER"
      },
      {
        "name": "Group B (Perturbation Based Training on Rolling Board)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Madinah Teaching Hospital and Al Mahmood Physiotherapy Clinic, Faisalabad, Faisalābad, Punjab Province, Pakistan"
    ],
    "start_date": "2026-05-20",
    "completion_date": "2026-09-20",
    "last_update": "2026-05-13",
    "topics": [
      "contrast-therapy"
    ],
    "topic_names": [
      "Contrast Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07598513"
  },
  {
    "nct_id": "NCT07596914",
    "title": "Multi-site Feasibility of an Integrated Treatment for the Biology and Experience of Depression: The MULTIBED Study",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Major Depressive Disorder"
    ],
    "interventions": [
      {
        "name": "Cognitive Behavioral Therapy (CBT)",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Whole-Body Hyperthermia",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "University of California, San Francisco, Osher Center for Integrative Health, San Francisco, California, United States",
      "Massachusetts General Hospital (MGH), Boston, Massachusetts, United States",
      "Cleveland Clinic Foundation, Cleveland, Ohio, United States"
    ],
    "start_date": "2026-08-01",
    "completion_date": "2029-03-31",
    "last_update": "2026-05-12",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07596914"
  },
  {
    "nct_id": "NCT06878989",
    "title": "Adaptation of Human Brown Adipose Tissue to Calorie Restriction",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Obesity and Overweight"
    ],
    "interventions": [
      {
        "name": "Caloric restriction diet",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Weight maintenance diet",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Department of Physiology, Faculty of Medicine, University of Granada., Granada, Granada, Spain"
    ],
    "start_date": "2025-01-25",
    "completion_date": "2026-12",
    "last_update": "2026-05-09",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06878989"
  },
  {
    "nct_id": "NCT05269589",
    "title": "Home-based Heat Therapy for Type 2 Diabetes",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 44,
    "conditions": [
      "Diabetes Mellitus, Type 2",
      "Heat Exposure"
    ],
    "interventions": [
      {
        "name": "Thermoneutral water",
        "type": "OTHER"
      },
      {
        "name": "Hot water",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Centre ÉPIC, Montreal Heart Institute, Montreal, Quebec, Canada"
    ],
    "start_date": "2022-02-18",
    "completion_date": "2027-12",
    "last_update": "2026-05-07",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05269589"
  },
  {
    "nct_id": "NCT07241559",
    "title": "Effectiveness of Thoracolumbar Fascia Mobilization and Ultrasound-Guided 5% Dextrose Injection in Chronic Low Back Pain",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 75,
    "conditions": [
      "Chronic Low Back Pain"
    ],
    "interventions": [
      {
        "name": "5% dextrose injection",
        "type": "DRUG"
      },
      {
        "name": "Myofascial Release",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Ankara Training and Research Hospital, Ankara, Altındağ, Turkey (Türkiye)"
    ],
    "start_date": "2025-11-01",
    "completion_date": "2026-07-01",
    "last_update": "2026-05-06",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07241559"
  },
  {
    "nct_id": "NCT05468151",
    "title": "Cold Acclimation as a Modulator of Brown Adipose Tissue Function in Adults With Obesity",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 45,
    "conditions": [
      "Obesity"
    ],
    "interventions": [
      {
        "name": "Cold acclimation",
        "type": "OTHER"
      },
      {
        "name": "Intervention Control group - volunteers with obesity",
        "type": "OTHER"
      },
      {
        "name": "Acute cold exposure",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Turku PET Centre, Turku, Turku, Finland"
    ],
    "start_date": "2022-07-25",
    "completion_date": "2026-12-01",
    "last_update": "2026-05-06",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05468151"
  },
  {
    "nct_id": "NCT06321991",
    "title": "Nodular Shrinking in Dupuytren Disease",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE2"
    ],
    "enrollment": 80,
    "conditions": [
      "Dupuytren's Disease"
    ],
    "interventions": [
      {
        "name": "Vitamin E-creme (Remederm®) vs Vaseline (Placebo)",
        "type": "DRUG"
      },
      {
        "name": "Ultrasound measurement",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "UZ Leuven, Leuven, Vlaams-Brabant, Belgium"
    ],
    "start_date": "2024-02-15",
    "completion_date": "2027-03-01",
    "last_update": "2026-05-05",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06321991"
  },
  {
    "nct_id": "NCT07575139",
    "title": "Myofascial Release and Dynamic Cupping in Children",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 45,
    "conditions": [
      "Neck Pain"
    ],
    "interventions": [
      {
        "name": "Myofascial release therapy",
        "type": "OTHER"
      },
      {
        "name": "dynamic cupping",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Imran Amjad, Lahore, Pakistan"
    ],
    "start_date": "2025-01-29",
    "completion_date": "2026-08-19",
    "last_update": "2026-05-04",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07575139"
  },
  {
    "nct_id": "NCT07573917",
    "title": "Improving Insulin Sensitivity in Patients With Type 2 Diabetes Via Repeated Cold-induced Shivering Thermogenesis",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 15,
    "conditions": [
      "Type 2 Diabetes"
    ],
    "interventions": [
      {
        "name": "Cold exposure with shivering",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Centre de recherche du CHUS, Sherbrooke, Quebec, Canada"
    ],
    "start_date": "2025-09-24",
    "completion_date": "2027-05-31",
    "last_update": "2026-05-04",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07573917"
  },
  {
    "nct_id": "NCT07576062",
    "title": "Efficacy of Cognitive Functional Therapy in Individuals With Chronic Low Back Pain After Spinal Surgery",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 90,
    "conditions": [
      "Chronic Low Back Pain",
      "After Lumbar Spine Surgery",
      "Failed Back Surgery Syndrome (FBSS)"
    ],
    "interventions": [
      {
        "name": "CFT",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Sham Detuned Photobiomodulation",
        "type": "DEVICE"
      }
    ],
    "locations": [],
    "start_date": "2026-05",
    "completion_date": "2027-11",
    "last_update": "2026-05-03",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07576062"
  },
  {
    "nct_id": "NCT07040397",
    "title": "Electronic Approach to the Human Massage Therapist",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Lower Back Pain"
    ],
    "interventions": [
      {
        "name": "EMMA massage therapy",
        "type": "DEVICE"
      },
      {
        "name": "Clinical massage treatment",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Mayo Clinic in Rochester, Rochester, Minnesota, United States"
    ],
    "start_date": "2026-01-30",
    "completion_date": "2026-10-01",
    "last_update": "2026-05-01",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07040397"
  },
  {
    "nct_id": "NCT07564440",
    "title": "Hyperthermia Safety Study Uses Temperature Management System to Gently Raise Participant's Body Temperature to a Fever-range Level in a Controlled Setting.",
    "status": "ENROLLING_BY_INVITATION",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 20,
    "conditions": [
      "Safety Study"
    ],
    "interventions": [
      {
        "name": "Hyperthermia",
        "type": "OTHER"
      }
    ],
    "locations": [
      "BTT Medical Institute LLC, Aventura, Florida, United States"
    ],
    "start_date": "2026-05",
    "completion_date": "2026-12",
    "last_update": "2026-04-29",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07564440"
  },
  {
    "nct_id": "NCT06916208",
    "title": "Study of the Effect of Capsinoid Supplementation on Brown Adipose Tissue in Obese Adolescents",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 38,
    "conditions": [
      "Obese Adolescents",
      "Exercise",
      "Diet Modification",
      "Dietary Supplement"
    ],
    "interventions": [
      {
        "name": "capsinoid supplementation",
        "type": "DIETARY_SUPPLEMENT"
      },
      {
        "name": "Control group (placebo)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Institut Saint Pierre, Palavas-les-Flots, France"
    ],
    "start_date": "2025-03-03",
    "completion_date": "2027-03",
    "last_update": "2026-04-29",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06916208"
  },
  {
    "nct_id": "NCT07286474",
    "title": "Effects of Laser Therapy and Vitamin D Pills on Braces Tooth Movement: A Random Controlled Study",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 50,
    "conditions": [
      "Malocclusion of Anterior Teeth"
    ],
    "interventions": [
      {
        "name": "Cholecalciferol (Vit D3)",
        "type": "DIETARY_SUPPLEMENT"
      },
      {
        "name": "Low-Level Laser Therapy",
        "type": "RADIATION"
      },
      {
        "name": "Fixed Orthodontic Appliance",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Armed Forces Hospital, Madinah, Madinah, Saudi Arabia"
    ],
    "start_date": "2026-01-01",
    "completion_date": "2026-12-31",
    "last_update": "2026-04-27",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07286474"
  },
  {
    "nct_id": "NCT07278999",
    "title": "Photobiomodulation, Photodynamic Therapy, and Clobetasol in the Treatment of Oral Lichen Planus.",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Oral Lichen Planus",
      "Erosive Lichen Planus",
      "Mucosal Lesions"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation using 635 nm diode laser",
        "type": "DEVICE"
      },
      {
        "name": "Photodynamic therapy - laser mucosal treatment",
        "type": "DEVICE"
      },
      {
        "name": "Clobetasol propionate 0.05 percent topical application",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Department of Periodontology and Oral Mucosa Diseases, Zabrze, Silesian Voivodeship, Poland"
    ],
    "start_date": "2025-12-01",
    "completion_date": "2026-11",
    "last_update": "2026-04-24",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07278999"
  },
  {
    "nct_id": "NCT07540312",
    "title": "A Prospective Trial of a Variable Compression System for Moderate to Severe Irritable Bowel Syndrome",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 20,
    "conditions": [
      "IBS (Irritable Bowel Syndrome)"
    ],
    "interventions": [
      {
        "name": "Variable Compression System",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Central Florida Gastro Research, Kissimmee, Florida, United States",
      "UChicago Medicine AdventHealth Medical Group Gastroenterology at Bolingbrook, Bolingbrook, Illinois, United States",
      "Delta Gastroenterology PC, Southhaven, Mississippi, United States"
    ],
    "start_date": "2025-05-21",
    "completion_date": "2026-05-01",
    "last_update": "2026-04-23",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07540312"
  },
  {
    "nct_id": "NCT07036705",
    "title": "Optimizing an Integrated Mind and Body Treatment for Insomnia: The SLEEPS Study 2",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Insomnia Disorder"
    ],
    "interventions": [
      {
        "name": "Cognitive Behavioral Therapy for Insomnia (CBT-I)",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Passive Body Heating (PBH)",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Osher Center for Integrative Health, San Francisco, California, United States"
    ],
    "start_date": "2025-09-29",
    "completion_date": "2027-07",
    "last_update": "2026-04-22",
    "topics": [
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07036705"
  },
  {
    "nct_id": "NCT07086638",
    "title": "ROS-Scavenging Nanozyme Combined With Thermotherapy Alleviate Radiation Dermatitis in Patients With Head and Neck Cancer",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 5,
    "conditions": [
      "Radiation Dermatitis"
    ],
    "interventions": [
      {
        "name": "Photo-responsive nanozyme",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Sichuan University West China Hospital, Chengdu, Sichuan, China"
    ],
    "start_date": "2025-07-25",
    "completion_date": "2026-10-25",
    "last_update": "2026-04-14",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07086638"
  },
  {
    "nct_id": "NCT07526649",
    "title": "Head Cooling in Ischaemic Stroke Patients Undergoing Endovascular Thrombectomy (COOLHEAD-2b)",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 182,
    "conditions": [
      "Stroke",
      "Acute Ischemic Stroke",
      "Brain Ischemia",
      "Ischaemic Stroke",
      "Thrombectomy",
      "Endovascular Procedures",
      "Reperfusion Injury",
      "Cooling",
      "Large Vessel Occlusion"
    ],
    "interventions": [
      {
        "name": "Non-invasive convective head cooling",
        "type": "DEVICE"
      },
      {
        "name": "Standard of Care (SOC)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Health New Zealand - Auckland, Grafton, Auckland, New Zealand"
    ],
    "start_date": "2026-04-10",
    "completion_date": "2029-06-30",
    "last_update": "2026-04-09",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07526649"
  },
  {
    "nct_id": "NCT06424132",
    "title": "Thermogenic Silencer Regulatory Factors in Humans",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 8,
    "conditions": [
      "Obesity",
      "Metabolic Disease",
      "Cold Exposure"
    ],
    "interventions": [
      {
        "name": "Cold Vest Exposure Period",
        "type": "OTHER"
      },
      {
        "name": "Rewarming Exposure Period",
        "type": "OTHER"
      },
      {
        "name": "Fasting",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Rockefeller University, New York, New York, United States"
    ],
    "start_date": "2024-08-16",
    "completion_date": "2026-12-04",
    "last_update": "2026-04-09",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06424132"
  },
  {
    "nct_id": "NCT07520929",
    "title": "Acute Sauna Session and Glucose Control",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 15,
    "conditions": [
      "Obesity & Overweight"
    ],
    "interventions": [
      {
        "name": "Infrared sauna session",
        "type": "OTHER"
      },
      {
        "name": "Resting condition",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Prince Edward Island, Charlottetown, Prince Edward Island, Canada"
    ],
    "start_date": "2025-12-01",
    "completion_date": "2027-04-15",
    "last_update": "2026-04-02",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07520929"
  },
  {
    "nct_id": "NCT07453927",
    "title": "Blue Light for Donor Site Healing in Burn Patients",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 25,
    "conditions": [
      "Donor Site Complication",
      "Burn",
      "Photobiomodulation Therapy",
      "Blue Light"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation with blue light",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "U.O. Centro Grandi Ustionati - Osp. Maurizio Bufalini, Cesena, Forlì-Cesena, Italy"
    ],
    "start_date": "2025-09-29",
    "completion_date": "2026-09-28",
    "last_update": "2026-03-31",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07453927"
  },
  {
    "nct_id": "NCT07511803",
    "title": "Photobiomodulation on Recovery in Female Futsal Athletes",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 15,
    "conditions": [
      "Muscle Recovery",
      "Exercise",
      "Phototherapy",
      "Futsal"
    ],
    "interventions": [
      {
        "name": "Active PBMT",
        "type": "DEVICE"
      },
      {
        "name": "Placebo PBMT",
        "type": "DEVICE"
      }
    ],
    "locations": [],
    "start_date": "2026-04-15",
    "completion_date": "2026-06-10",
    "last_update": "2026-03-30",
    "topics": [
      "exercise-recovery",
      "photobiomodulation"
    ],
    "topic_names": [
      "Exercise Recovery",
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07511803"
  },
  {
    "nct_id": "NCT07511790",
    "title": "Photobiomodulation on Performance in Female Futsal Athletes",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 15,
    "conditions": [
      "Muscle Performance",
      "Exercise",
      "Phototherapy",
      "Futsal"
    ],
    "interventions": [
      {
        "name": "Active PBMT",
        "type": "DEVICE"
      },
      {
        "name": "Placebo PBMT",
        "type": "DEVICE"
      }
    ],
    "locations": [],
    "start_date": "2026-04-15",
    "completion_date": "2026-06-10",
    "last_update": "2026-03-30",
    "topics": [
      "exercise-recovery",
      "photobiomodulation"
    ],
    "topic_names": [
      "Exercise Recovery",
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07511790"
  },
  {
    "nct_id": "NCT06822478",
    "title": "Arnica Tincture Fot the Treatment of Cutaneous Leishmaniasis II.",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE3"
    ],
    "enrollment": 96,
    "conditions": [
      "Leishmaniasis, Cutaneous"
    ],
    "interventions": [
      {
        "name": "Arnica Tincture",
        "type": "DRUG"
      },
      {
        "name": "Meglumine antimoniate.",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Grupo de Investigación Clínica PECET (GIC-PECET), Medellín, Antioquia, Colombia"
    ],
    "start_date": "2026-03-11",
    "completion_date": "2030-02",
    "last_update": "2026-03-27",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06822478"
  },
  {
    "nct_id": "NCT06815367",
    "title": "Pneumatic Compression vs Blood Flow Restriction for Muscle Recovery",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 33,
    "conditions": [
      "Delayed Onset Muscle Soreness"
    ],
    "interventions": [
      {
        "name": "Pneumatic Compression",
        "type": "DEVICE"
      },
      {
        "name": "Blood Flow Restriction",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "University of Southern California, Los Angeles, California, United States"
    ],
    "start_date": "2024-01-15",
    "completion_date": "2026-05-01",
    "last_update": "2026-03-24",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06815367"
  },
  {
    "nct_id": "NCT07482189",
    "title": "Effectiveness and Efficiency of an Upper Limb Active-Passive Exoskeleton Robot in Patients With Frozen Shoulder",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Adhesive Capsulitis of the Shoulder",
      "Frozen Shoulder"
    ],
    "interventions": [
      {
        "name": "Upper limb exoskeleton-assisted therapy",
        "type": "PROCEDURE"
      },
      {
        "name": "General physical therapies",
        "type": "PROCEDURE"
      },
      {
        "name": "Traditional physical therapies",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Asia University Hospital, Taichung, Wufeng Dist., Taiwan"
    ],
    "start_date": "2026-03-16",
    "completion_date": "2027-03-15",
    "last_update": "2026-03-21",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07482189"
  },
  {
    "nct_id": "NCT07118904",
    "title": "Effect of Dehydration on Sleep Quality, Cognitive Skills, and Electromyographic Responses in Combat Athletes",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 12,
    "conditions": [
      "Dehydration",
      "Weight Loss",
      "Weight Cycling",
      "Sleep"
    ],
    "interventions": [
      {
        "name": "Rapid weight loss through dehydration",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Bolu Abant İzzet Baysal University, Faculty of Sport Sciences,, Bolu, Turkey (Türkiye)"
    ],
    "start_date": "2025-08-18",
    "completion_date": "2026-08-30",
    "last_update": "2026-03-12",
    "topics": [
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07118904"
  },
  {
    "nct_id": "NCT06565221",
    "title": "Microvascular Blood Flow During Passive Heating",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 50,
    "conditions": [
      "Blood Flow"
    ],
    "interventions": [
      {
        "name": "Heat and negative pressure",
        "type": "DEVICE"
      }
    ],
    "locations": [],
    "start_date": "2026-08",
    "completion_date": "2026-12",
    "last_update": "2026-03-11",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06565221"
  },
  {
    "nct_id": "NCT07460895",
    "title": "Effectiveness of Photobiomodulation for Myofascial Pain in Temporomandibular Disorders",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 140,
    "conditions": [
      "Photobiomodulation",
      "Temporomandibular Disorder (TMD)",
      "Myofacial Pain",
      "Pain Management"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation Therapy",
        "type": "DEVICE"
      },
      {
        "name": "Therapeutic Exercises",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Sham Photobiomodulation Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [],
    "start_date": "2026-03-10",
    "completion_date": "2030-12",
    "last_update": "2026-03-05",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07460895"
  },
  {
    "nct_id": "NCT07453238",
    "title": "Comparison of Topical Calcipotriol and Intralesional Steroids in Alopecia Areata",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE4"
    ],
    "enrollment": 60,
    "conditions": [
      "Alopecia Areata"
    ],
    "interventions": [
      {
        "name": "Calcipotriol",
        "type": "DRUG"
      },
      {
        "name": "Triamcinolone Acetonide",
        "type": "DRUG"
      }
    ],
    "locations": [],
    "start_date": "2026-04-01",
    "completion_date": "2026-10-01",
    "last_update": "2026-03-02",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07453238"
  },
  {
    "nct_id": "NCT07158047",
    "title": "Repeated Far Infrared Sauna Bathing in Adults With Obesity",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 20,
    "conditions": [
      "Obesity (Disorder)"
    ],
    "interventions": [
      {
        "name": "Heat therapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Oregon, Eugene, Oregon, United States"
    ],
    "start_date": "2022-03-07",
    "completion_date": "2026-07-31",
    "last_update": "2026-03-02",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07158047"
  },
  {
    "nct_id": "NCT06146816",
    "title": "The Assessment of Infrared Treatment for Crohn's Disease",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "IBD",
      "Inflammatory Bowel Diseases",
      "Crohn Disease"
    ],
    "interventions": [
      {
        "name": "High level photobiomodulation treatment in the infrared (IR) range.",
        "type": "DEVICE"
      },
      {
        "name": "Medium level photobiomodulation treatment in the far infrared (IR) range",
        "type": "DEVICE"
      },
      {
        "name": "Low level photobiomodulation treatment in the far infrared (IR) range",
        "type": "DEVICE"
      },
      {
        "name": "Photobiomodulation sham treatment",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Dep. of Gastroenterology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel"
    ],
    "start_date": "2023-09-12",
    "completion_date": "2028-01",
    "last_update": "2026-02-22",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06146816"
  },
  {
    "nct_id": "NCT07433036",
    "title": "The Effectiveness of Emergency Room Protocols for Treating Hyperthermia",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 50,
    "conditions": [
      "Hyperthermia"
    ],
    "interventions": [
      {
        "name": "Passive cooling",
        "type": "PROCEDURE"
      },
      {
        "name": "Cooling packs",
        "type": "PROCEDURE"
      },
      {
        "name": "Ice sheets",
        "type": "PROCEDURE"
      },
      {
        "name": "Body bag cooling",
        "type": "PROCEDURE"
      },
      {
        "name": "Cold water immersion",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "University of Colorado Colorado Springs, Colorado Springs, Colorado, United States"
    ],
    "start_date": "2025-07-01",
    "completion_date": "2028-12-31",
    "last_update": "2026-02-18",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07433036"
  },
  {
    "nct_id": "NCT07423182",
    "title": "Effects of Carbon Dioxide Infrared Laser Moxibustion on Pain and Function in Knee Osteoarthritis",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 68,
    "conditions": [
      "Knee Osteoarthritis"
    ],
    "interventions": [
      {
        "name": "Exercise Program for Knee Osteoarthritis",
        "type": "OTHER"
      },
      {
        "name": "CO2 Infrared Laser Moxibustion (CILM)",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Rashid Latif Medical College, Lahore, Pakistan, Lahore, Pakistan"
    ],
    "start_date": "2025-10-26",
    "completion_date": "2026-07-30",
    "last_update": "2026-02-18",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07423182"
  },
  {
    "nct_id": "NCT07376616",
    "title": "Cardiovascular Research in EMbarazo and MAternity (EMMA). Study on Heart Rate Variability and Hemodynamic Adaptations During Pregnancy and Postpartum.",
    "status": "RECRUITING",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 242,
    "conditions": [
      "Pregnancy Related",
      "Heart Rate Variation (HRV)",
      "Hemodynamics"
    ],
    "interventions": [
      {
        "name": "Assessment of HRV and blood pressure",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Hospital Alvaro Cunqueiro, Vigo, Pontevedra, Spain"
    ],
    "start_date": "2025-05-19",
    "completion_date": "2027-12-15",
    "last_update": "2026-02-12",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07376616"
  },
  {
    "nct_id": "NCT03750409",
    "title": "Assessing Feasibility of Prolonged Repetitive Near Infrared Light Stimulation in Early to Mid-Stage Dementia",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 100,
    "conditions": [
      "Mild to Moderate Dementia"
    ],
    "interventions": [
      {
        "name": "Helmet",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Quietmind Foundation, Elkins Park, Pennsylvania, United States",
      "Baylor Scott and White Medical Center, Temple, Temple, Texas, United States"
    ],
    "start_date": "2018-10-15",
    "completion_date": "2026-07-15",
    "last_update": "2026-02-09",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03750409"
  },
  {
    "nct_id": "NCT07396233",
    "title": "Effects of Diagonal Proprioceptive Neuromuscular Facilitation Patterns on Pain and Functional Outcomes in Patients With Knee Osteoarthritis",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 150,
    "conditions": [
      "Knee Osteoarthristis",
      "Osteearthritis",
      "Knee Pain Arthritis"
    ],
    "interventions": [
      {
        "name": "Diagonal Proprioceptive Neuromuscular Facilitation (PNF) Pattern Exercises",
        "type": "OTHER"
      },
      {
        "name": "Conventional Strength Training Exercises",
        "type": "OTHER"
      },
      {
        "name": "Heat Therapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Al-Rayaz Hospital, Karachi, Sindh, Pakistan",
      "Dr. Ziauddin Hospital, Karachi, Sindh, Pakistan"
    ],
    "start_date": "2026-02-07",
    "completion_date": "2027-02-22",
    "last_update": "2026-02-07",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07396233"
  },
  {
    "nct_id": "NCT07080320",
    "title": "Research on the Evolution, Geometry, and Alterations of the Periorbital Region Based on Age and Deformations",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Facial Skin",
      "Motion Capture",
      "Aging",
      "Periorbital Region",
      "Skin Movement",
      "Vertical Jump"
    ],
    "interventions": [
      {
        "name": "MoCap",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "CHRU Amiens, Amiens, France"
    ],
    "start_date": "2025-09-20",
    "completion_date": "2027-09",
    "last_update": "2026-02-04",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07080320"
  },
  {
    "nct_id": "NCT07068347",
    "title": "Comparison Of VR & CPT, With And Without Lifestyle Modification, On ULD In Breast Cancer Survivors",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Breast Cancer"
    ],
    "interventions": [
      {
        "name": "VR + lifestyle modification",
        "type": "COMBINATION_PRODUCT"
      },
      {
        "name": "VR only",
        "type": "COMBINATION_PRODUCT"
      },
      {
        "name": "Conventional physical therapy + lifestyle modification",
        "type": "COMBINATION_PRODUCT"
      },
      {
        "name": "Conventional physical therapy only",
        "type": "COMBINATION_PRODUCT"
      }
    ],
    "locations": [
      "District Head Quarters Hospital, Rawalpindi, Punjab Province, Pakistan",
      "Holy Family Hospital, Rawalpindi, Punjab Province, Pakistan",
      "Kinifit Physiotherapy Center, Islamabad, Pakistan"
    ],
    "start_date": "2025-04-17",
    "completion_date": "2026-06-01",
    "last_update": "2026-01-29",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07068347"
  },
  {
    "nct_id": "NCT05206227",
    "title": "Histamine as a Molecular Transducer of Adaptation to Exercise",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "EARLY_PHASE1"
    ],
    "enrollment": 80,
    "conditions": [
      "Postexercise Hypotension"
    ],
    "interventions": [
      {
        "name": "Aerobic Exercise",
        "type": "BEHAVIORAL"
      },
      {
        "name": "alpha-FMH",
        "type": "DRUG"
      },
      {
        "name": "Resistance and Aerobic Exercise",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Antihistamine",
        "type": "DRUG"
      }
    ],
    "locations": [
      "University of Oregon, Eugene, Oregon, United States"
    ],
    "start_date": "2021-07-28",
    "completion_date": "2027-03-31",
    "last_update": "2026-01-21",
    "topics": [
      "exercise-recovery",
      "infrared-sauna"
    ],
    "topic_names": [
      "Exercise Recovery",
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05206227"
  },
  {
    "nct_id": "NCT07372443",
    "title": "Photobiomodulation in the Prevention and Management of Oral Mucositis in Children",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 49,
    "conditions": [
      "Oral Mucositis",
      "Chemotherapy Effect",
      "Pediatric Cancer"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation",
        "type": "DEVICE"
      },
      {
        "name": "bioadhesive gel",
        "type": "DRUG"
      }
    ],
    "locations": [],
    "start_date": "2026-01",
    "completion_date": "2027-08",
    "last_update": "2026-01-19",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07372443"
  },
  {
    "nct_id": "NCT04368689",
    "title": "The Feasibility and Examination of the Effects of Floatation-based REST on a Community Sample With PTSD",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Post-Traumatic Stress Disorders"
    ],
    "interventions": [
      {
        "name": "Floatation-based reduced environmental stimulation therapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Medical College of Wisconsin, Milwaukee, Wisconsin, United States"
    ],
    "start_date": "2021-06-18",
    "completion_date": "2027-12",
    "last_update": "2026-01-19",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04368689"
  },
  {
    "nct_id": "NCT06956404",
    "title": "tPBM in Older Adults With Traumatic Brain Injury",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 70,
    "conditions": [
      "Traumatic Brain Injury"
    ],
    "interventions": [
      {
        "name": "Transcranial photobiomodulator (tPBM)",
        "type": "DEVICE"
      },
      {
        "name": "Transcranial photobiomodulator (tPBM) in sham mode",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "NYU Langone Health, New York, New York, United States"
    ],
    "start_date": "2025-12-29",
    "completion_date": "2028-07",
    "last_update": "2026-01-14",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06956404"
  },
  {
    "nct_id": "NCT07334938",
    "title": "Effects of Far Infrared Rays and Transcutaneous Electrical Nerve Stimulation on Short Term Prognosis of Head and Neck Cancer Patients Receiving Curative Treatment",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 90,
    "conditions": [
      "Head and Neck Cancer (H&N)"
    ],
    "interventions": [
      {
        "name": "Transcutaneous Electrical Nerve Stimulation (TENS)",
        "type": "DEVICE"
      },
      {
        "name": "Far-Infrared Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien City, Hualien County, Taiwan"
    ],
    "start_date": "2024-05-01",
    "completion_date": "2026-03-31",
    "last_update": "2026-01-11",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07334938"
  },
  {
    "nct_id": "NCT07332988",
    "title": "Effect of Low-Level Light Therapy on Ocular Surface Parameters in Patients With Graves Disease",
    "status": "ENROLLING_BY_INVITATION",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Dry Eye Disease (DED)",
      "Graves Ophthalmopathy"
    ],
    "interventions": [
      {
        "name": "Sham (No Treatment)",
        "type": "DEVICE"
      },
      {
        "name": "Low Light Level therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "University of Medicine and Pharmacy \"Grigore T. Popa\", Iași, Iaşi, Romania"
    ],
    "start_date": "2025-08-01",
    "completion_date": "2026-08",
    "last_update": "2026-01-09",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07332988"
  },
  {
    "nct_id": "NCT07346651",
    "title": "Percussive Massage Therapy Using Heat Attachment in Chronic Low Back Pain",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 48,
    "conditions": [
      "Chronic Low Back Pain (CLBP)"
    ],
    "interventions": [
      {
        "name": "Percussive Massage Therapy",
        "type": "DEVICE"
      },
      {
        "name": "Exercise Training (Conventional Rehabilitation)",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Transcutaneous Electrical Nerve Stimulation (Conventional Rehabilitation)",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Göztepe Prof. Dr. Süleyman Yalçın City Hospital, Istanbul, Turkey (Türkiye)"
    ],
    "start_date": "2026-01-12",
    "completion_date": "2026-08",
    "last_update": "2026-01-08",
    "topics": [
      "massage-therapy",
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Massage Therapy",
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07346651"
  },
  {
    "nct_id": "NCT06160947",
    "title": "The Effect of Chiropractic Care on Opioid Use for Chronic Spinal Pain: A Feasibility Study",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 24,
    "conditions": [
      "Back Pain"
    ],
    "interventions": [
      {
        "name": "Usual Medical Care",
        "type": "OTHER"
      },
      {
        "name": "Usual Medical Care + Chiropractic Care",
        "type": "OTHER"
      }
    ],
    "locations": [
      "McMaster University, Hamilton, Ontario, Canada"
    ],
    "start_date": "2026-04-01",
    "completion_date": "2028-03-31",
    "last_update": "2026-01-05",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06160947"
  },
  {
    "nct_id": "NCT05465070",
    "title": "Leg Heat Therapy in Peripheral Artery Disease",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 106,
    "conditions": [
      "Peripheral Artery Disease"
    ],
    "interventions": [
      {
        "name": "Leg heat therapy",
        "type": "DEVICE"
      },
      {
        "name": "Sham Control",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Indiana University Health Methodist Hospital, Indianapolis, Indiana, United States"
    ],
    "start_date": "2022-11-07",
    "completion_date": "2026-12-31",
    "last_update": "2026-01-04",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05465070"
  },
  {
    "nct_id": "NCT07203339",
    "title": "Home-based Transcranial Direct Current Stimulation (tDCS) Compared to Duloxetine: Non-inferiority Clinical Trial (FIBROSTIM)",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 610,
    "conditions": [
      "Fibromyalgia (FM)",
      "tDCS",
      "Duloxetine",
      "BDNF",
      "EEG"
    ],
    "interventions": [
      {
        "name": "Transcranial direct current stimulation (tDCS) plus placebo.",
        "type": "DEVICE"
      },
      {
        "name": "Duloxetine (60 mg) once daily",
        "type": "DRUG"
      },
      {
        "name": "Home-based transcranial direct current stimulation",
        "type": "DEVICE"
      },
      {
        "name": "Duloxetine 60 mg",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil"
    ],
    "start_date": "2025-09-30",
    "completion_date": "2028-12",
    "last_update": "2025-12-31",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07203339"
  },
  {
    "nct_id": "NCT07317856",
    "title": "Efficacy of Microneedling With Hyaluronic Acid Injection for Gingival Augmentation in Thin Gingival Phenotype",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 20,
    "conditions": [
      "Thin Gingival Biotype"
    ],
    "interventions": [
      {
        "name": "Microneedling (MN)",
        "type": "PROCEDURE"
      },
      {
        "name": "Microneedling + Injectable Hyaluronic Acid (MN + HA)",
        "type": "COMBINATION_PRODUCT"
      }
    ],
    "locations": [
      "University of Baghdad, Baghdad, Iraq"
    ],
    "start_date": "2026-01",
    "completion_date": "2026-09",
    "last_update": "2025-12-19",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07317856"
  },
  {
    "nct_id": "NCT07287527",
    "title": "Effects of Photobiomodularion on Brain Connectivity and Cognitive Function in Cognitive Impairment",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "AMCI - Amnestic Mild Cognitive Impairment"
    ],
    "interventions": [
      {
        "name": "Active transcranial Photobiomodulation",
        "type": "DEVICE"
      },
      {
        "name": "sham transcranial Photobiomodulation",
        "type": "DEVICE"
      },
      {
        "name": "Cognitive Rehabilitation",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "NPIstanbul Brain Hospital, Istanbul, Turkey (Türkiye)",
      "Uskudar University, Faculty of Medicine, Istnabul, Turkey (Türkiye)"
    ],
    "start_date": "2024-03-30",
    "completion_date": "2026-10",
    "last_update": "2025-12-13",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07287527"
  },
  {
    "nct_id": "NCT07274371",
    "title": "A Study Comparing the Effects of Two Types of Natural Oils Used in a Bedtime Foot Massage Routine on Sleep and Emotional Well-Being in Perimenopausal Women.",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Sleep Disturbances in Perimenopause"
    ],
    "interventions": [
      {
        "name": "Brahmi-Gotukola oil padabhyanga",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Sesame oil Padabhyanga",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Maharishi International University, Fairfield, Iowa, United States"
    ],
    "start_date": "2025-11-06",
    "completion_date": "2026-04-30",
    "last_update": "2025-12-11",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07274371"
  },
  {
    "nct_id": "NCT07271160",
    "title": "The Effect of Aromatherapy Foot Massage on Neuropathic Pain in Patients With Type2 Diabetes",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 78,
    "conditions": [
      "Type 2 Diabetes Mellitus (T2DM)",
      "Neuropathic Pain"
    ],
    "interventions": [
      {
        "name": "intervention I group",
        "type": "OTHER"
      },
      {
        "name": "Intervention II group",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Nevsehir State Hospital, Nevşehir, Nevşehir Province, Turkey (Türkiye)"
    ],
    "start_date": "2025-12-01",
    "completion_date": "2026-05-15",
    "last_update": "2025-12-07",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07271160"
  },
  {
    "nct_id": "NCT07278791",
    "title": "Survey-Based Study on Recovery Period Differences in Upper Extremity Injuries Among Indoor Climbers by Treatment Method",
    "status": "NOT_YET_RECRUITING",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 300,
    "conditions": [
      "Upper Extremity Injury"
    ],
    "interventions": [],
    "locations": [],
    "start_date": "2025-12-01",
    "completion_date": "2026-04-30",
    "last_update": "2025-12-01",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07278791"
  },
  {
    "nct_id": "NCT07266636",
    "title": "Effects of Photobiomodulation and Electrical Stimulation Among Bell's Palsy Patients",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 34,
    "conditions": [
      "Bell's Palsy"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation alongwith facial exercise",
        "type": "RADIATION"
      },
      {
        "name": "Electrical Stimulation alongwith facial exercise",
        "type": "OTHER"
      }
    ],
    "locations": [],
    "start_date": "2025-11-25",
    "completion_date": "2026-05-25",
    "last_update": "2025-11-24",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07266636"
  },
  {
    "nct_id": "NCT07248475",
    "title": "Effects of Battle Rope Training on ROM and Pain in Children With Post Traumatic Elbow Contractures.",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 42,
    "conditions": [
      "Children, Adult"
    ],
    "interventions": [
      {
        "name": "Battle Rope Training",
        "type": "OTHER"
      },
      {
        "name": "Stretching and Heat Therapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Imran Amjad, Lahore, Punjab Province, Pakistan"
    ],
    "start_date": "2025-10-29",
    "completion_date": "2026-01-30",
    "last_update": "2025-11-18",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07248475"
  },
  {
    "nct_id": "NCT07242183",
    "title": "Acute Effects of Hot-Pack Therapy in Low Back Pain",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 24,
    "conditions": [
      "Low Back Pain",
      "Back Pain"
    ],
    "interventions": [
      {
        "name": "Hot-Pack",
        "type": "DEVICE"
      },
      {
        "name": "Sham Pack",
        "type": "DEVICE"
      }
    ],
    "locations": [],
    "start_date": "2025-11-10",
    "completion_date": "2025-12-30",
    "last_update": "2025-11-17",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07242183"
  },
  {
    "nct_id": "NCT07224607",
    "title": "Transcranial Photobiomodulation (tPBM) in Alzheimer's Disease Study",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 45,
    "conditions": [
      "Alzheimer's Disease"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "CSMC, Los Angeles, California, United States"
    ],
    "start_date": "2025-12-25",
    "completion_date": "2026-10",
    "last_update": "2025-11-17",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07224607"
  },
  {
    "nct_id": "NCT07237087",
    "title": "Masseter Muscle Stiffness After Heat Application and Percussion Therapy",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Healthy Participants"
    ],
    "interventions": [
      {
        "name": "massage gun",
        "type": "DEVICE"
      },
      {
        "name": "heat treatment",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Zentrum für Zahnmedizin, Zurich, Canton of Zurich, Switzerland"
    ],
    "start_date": "2025-11-15",
    "completion_date": "2026-03-31",
    "last_update": "2025-11-14",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07237087"
  },
  {
    "nct_id": "NCT06263738",
    "title": "Cold and Heat Investigation to Lower Levels of Depression",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 162,
    "conditions": [
      "Depression",
      "Mood Disorders",
      "Healthy (Controls)"
    ],
    "interventions": [
      {
        "name": "Whole Body Hyperthermia",
        "type": "PROCEDURE"
      },
      {
        "name": "Cold Water Plunge",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Vail Health Behavioral Health Innovation Center, Edwards, Colorado, United States"
    ],
    "start_date": "2024-05-14",
    "completion_date": "2027-04-01",
    "last_update": "2025-11-11",
    "topics": [
      "infrared-sauna",
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Infrared Sauna",
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06263738"
  },
  {
    "nct_id": "NCT05931497",
    "title": "Sauna for Long Covid",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 21,
    "conditions": [
      "Long COVID"
    ],
    "interventions": [
      {
        "name": "whole body hyperthermia",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Depression Clinical and Research Program, Boston, Massachusetts, United States"
    ],
    "start_date": "2026-08-01",
    "completion_date": "2026-12-01",
    "last_update": "2025-11-11",
    "topics": [
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05931497"
  },
  {
    "nct_id": "NCT02909192",
    "title": "Bright Light Therapy for Non-motor Symptoms in Parkinson's Disease",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 65,
    "conditions": [
      "Parkinson's Disease"
    ],
    "interventions": [
      {
        "name": "Light Therapy Device",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Massachusetts General Hospital, Boston, Massachusetts, United States"
    ],
    "start_date": "2016-12",
    "completion_date": "2026-11",
    "last_update": "2025-11-04",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02909192"
  },
  {
    "nct_id": "NCT06232304",
    "title": "Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 175,
    "conditions": [
      "Systemic Lupus Erythematosus of Childhood (Disorder)"
    ],
    "interventions": [
      {
        "name": "TEACH",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "University of Alabama Birmingham Hospital, Birmingham, Alabama, United States",
      "Children's Hospital of New Orleans/ Tulane University, New Orleans, Louisiana, United States",
      "Helen Devos Children's Hospital, Grand Rapids, Michigan, United States",
      "Montefiore Medical Center, The Bronx, New York, United States",
      "Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States",
      "Seattle Children's Hospital, Seattle, Washington, United States",
      "The Hospital for Sick Children, Toronto, Ontario, Canada"
    ],
    "start_date": "2024-09-12",
    "completion_date": "2027-09-30",
    "last_update": "2025-10-28",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06232304"
  },
  {
    "nct_id": "NCT07154732",
    "title": "Transcranial Photobiomodulation With Multiple Interventions in Children With Attention-Deficit/Hyperactivity Disorder",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 54,
    "conditions": [
      "Attention Deficit Hyperactivity Disorder (ADHD)"
    ],
    "interventions": [
      {
        "name": "Transcranial photobiomodulation (active)",
        "type": "DEVICE"
      },
      {
        "name": "Transcranial photobiomodulation (sham)",
        "type": "DEVICE"
      }
    ],
    "locations": [],
    "start_date": "2025-10-01",
    "completion_date": "2027-01-30",
    "last_update": "2025-09-30",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07154732"
  },
  {
    "nct_id": "NCT06332963",
    "title": "Interoceptive Mechanisms of Body Image Disturbance in Anorexia Nervosa",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 102,
    "conditions": [
      "Anorexia Nervosa",
      "Body Image Disturbance",
      "Interoception"
    ],
    "interventions": [
      {
        "name": "Floatation-REST",
        "type": "BEHAVIORAL"
      },
      {
        "name": "IFT",
        "type": "BEHAVIORAL"
      },
      {
        "name": "EFT",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Laureate Institute for Brain Research, Tulsa, Oklahoma, United States"
    ],
    "start_date": "2024-04-19",
    "completion_date": "2028-12",
    "last_update": "2025-09-25",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06332963"
  },
  {
    "nct_id": "NCT06506253",
    "title": "Massage for GAD: Neuroimaging and Clinical Correlates of Response",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 46,
    "conditions": [
      "Generalized Anxiety Disorder"
    ],
    "interventions": [
      {
        "name": "Swedish Massage Therapy",
        "type": "OTHER"
      },
      {
        "name": "Light Touch Therapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Huntsman Mental Health Institute, Salt Lake City, Utah, United States"
    ],
    "start_date": "2024-05-01",
    "completion_date": "2026-08",
    "last_update": "2025-09-08",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06506253"
  },
  {
    "nct_id": "NCT07165405",
    "title": "Effects of Hot Sacral Massage and Shower Application With Partner Support on Labor",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 150,
    "conditions": [
      "Pain",
      "Experience",
      "Comfort"
    ],
    "interventions": [
      {
        "name": "Shower",
        "type": "OTHER"
      },
      {
        "name": "Massage",
        "type": "OTHER"
      },
      {
        "name": "Midwifery Care",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Istanbul University-Cerrahpaşa, Istanbul, Büyükçekmece, Turkey (Türkiye)"
    ],
    "start_date": "2025-02-01",
    "completion_date": "2025-09-30",
    "last_update": "2025-09-03",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07165405"
  },
  {
    "nct_id": "NCT07082166",
    "title": "Comparison of the Effects of Fibromyalgia Syndrome",
    "status": "NOT_YET_RECRUITING",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 32,
    "conditions": [
      "Fibromyalgia"
    ],
    "interventions": [],
    "locations": [
      "Istanbul Gerontechnology Research Center, Istanbul, Turkey (Türkiye)"
    ],
    "start_date": "2025-10-20",
    "completion_date": "2026-06-12",
    "last_update": "2025-08-17",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07082166"
  },
  {
    "nct_id": "NCT07128134",
    "title": "Evaluation of the Effects of the Low-level Laser Therapy as an Adjunct to Nonsurgical Treatment in Patients With Periimplantitis",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 72,
    "conditions": [
      "Periimplantitis"
    ],
    "interventions": [
      {
        "name": "Low Level Laser Therapy",
        "type": "DEVICE"
      },
      {
        "name": "Non-surgical Periodontal Treatment",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Hatay Mustafa Kemal University, Hatay, Turkey (Türkiye)"
    ],
    "start_date": "2025-08-20",
    "completion_date": "2026-06-30",
    "last_update": "2025-08-15",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07128134"
  },
  {
    "nct_id": "NCT03541096",
    "title": "Winter-Swimming and Brown Adipose Tissue Activity in Middel-aged Obese Subjects (WinterBAT).",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Adipose Tissue, Brown",
      "Brown Adipose Tissue",
      "Uncoupling Protein 1",
      "Cold Exposure",
      "Obesity",
      "Type 2 Diabetes Mellitus",
      "Winter Swimming"
    ],
    "interventions": [
      {
        "name": "Winter Swimming",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Control group",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Center for Inflammation and Metabolism/ Center for Physical Activity Research, Copenhagen, Denmark"
    ],
    "start_date": "2018-11-07",
    "completion_date": "2025-12-31",
    "last_update": "2025-08-12",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03541096"
  },
  {
    "nct_id": "NCT07117643",
    "title": "Ischemic Preconditioning - Perspectives of Use Vivio/in Vitro Studies",
    "status": "ENROLLING_BY_INVITATION",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 250,
    "conditions": [
      "Sport Medicine",
      "Sport",
      "Physiological Adaptations",
      "Sport Performance",
      "Remote Ischemic Preconditioning",
      "Ischemic Preconditioning"
    ],
    "interventions": [
      {
        "name": "Ischemic Preconditioning",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Gdansk University of Physical Education and Sport, Gdansk, Pomeranian Voivodeship, Poland",
      "University of Physical Education and Sport (GUPES), Gdansk, Pomeranian Voivodeship, Poland"
    ],
    "start_date": "2025-01-01",
    "completion_date": "2029-01-01",
    "last_update": "2025-08-04",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07117643"
  },
  {
    "nct_id": "NCT07098741",
    "title": "Comparing Different Physiotherapy Interventions on APT in Non Specific Low Back Pain",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 100,
    "conditions": [
      "Anterior Pelvic Tilt",
      "Low Back Pain"
    ],
    "interventions": [
      {
        "name": "Core stability exercises with electrotherapy",
        "type": "OTHER"
      },
      {
        "name": "Soft tissue release with manual therapy and stretching",
        "type": "OTHER"
      },
      {
        "name": "Postural correction exercises with contrast therapy",
        "type": "OTHER"
      },
      {
        "name": "combination of electrotherapy with stretching and flexibility exercises",
        "type": "OTHER"
      }
    ],
    "locations": [
      "National Orthopedic & General Hospital, Chak Four Hundred Fifty-four, Punjab Province, Pakistan"
    ],
    "start_date": "2025-03-20",
    "completion_date": "2025-10-15",
    "last_update": "2025-07-29",
    "topics": [
      "contrast-therapy"
    ],
    "topic_names": [
      "Contrast Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07098741"
  },
  {
    "nct_id": "NCT07101042",
    "title": "Cold vs. Paraspinal Stimulation for Erectile and Urinary Function in SCI Patients",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Spinal Cord Injury"
    ],
    "interventions": [
      {
        "name": "Cold Stimulation",
        "type": "OTHER"
      },
      {
        "name": "Paraspinal Electrical Stimulation",
        "type": "OTHER"
      }
    ],
    "locations": [],
    "start_date": "2025-09-01",
    "completion_date": "2025-10-10",
    "last_update": "2025-07-28",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07101042"
  },
  {
    "nct_id": "NCT07091773",
    "title": "A Clinical Trial to Evaluate the Safety and Effectiveness of OLIZ, a Photobiomodulation Medical Device for Surgical Site Pain Relief in Patients After Total Knee Arthroplasty",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 68,
    "conditions": [
      "Postoperative Pain Management During Rehabilitation in Patients Undergoing Total Knee Arthroplasty"
    ],
    "interventions": [
      {
        "name": "OLIZ Photobiomodulation Device",
        "type": "DEVICE"
      }
    ],
    "locations": [],
    "start_date": "2025-08-20",
    "completion_date": "2026-06-30",
    "last_update": "2025-07-28",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07091773"
  },
  {
    "nct_id": "NCT06761937",
    "title": "Thermoradiotherapy for Locally Advanced Head and Neck Cancer Patients",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 30,
    "conditions": [
      "Head and Neck Cancer",
      "Oropharyngeal Carcinoma",
      "Hypopharyngeal Carcinoma",
      "Laryngeal Cancer",
      "Head and Neck Squamous Cell Carcinoma"
    ],
    "interventions": [
      {
        "name": "Thermotherapy",
        "type": "PROCEDURE"
      },
      {
        "name": "standard radiotherapy",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "Erasmus MC, Rotterdam, South Holland, Netherlands"
    ],
    "start_date": "2025-05-01",
    "completion_date": "2028-10-31",
    "last_update": "2025-07-22",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06761937"
  },
  {
    "nct_id": "NCT06239818",
    "title": "Assessing the Effects of Photobiomodulation on Clinical Recovery From Concussion in Adolescents",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Sports-related Concussion"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation therapy (PBMt)",
        "type": "DEVICE"
      },
      {
        "name": "Standard of Care",
        "type": "OTHER"
      }
    ],
    "locations": [
      "The University of Texas Health Science Center at Houston, Houston, Texas, United States"
    ],
    "start_date": "2024-04-17",
    "completion_date": "2026-04-01",
    "last_update": "2025-07-16",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06239818"
  },
  {
    "nct_id": "NCT07046416",
    "title": "Effectiveness of Occupation-Based Exercise Program in Zone 2 Flexor Tendon Injuries",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 65,
    "conditions": [
      "Tendon Injuries",
      "Zone 2 Flexor Tendon Lacerations of the Hand"
    ],
    "interventions": [
      {
        "name": "Occupation-Based Exercise Program",
        "type": "OTHER"
      },
      {
        "name": "Conventional therapy group",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Istanbul Unıversity, Istanbul Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Istanbul, Turkey (Türkiye)"
    ],
    "start_date": "2025-07",
    "completion_date": "2025-12",
    "last_update": "2025-07-04",
    "topics": [
      "contrast-therapy"
    ],
    "topic_names": [
      "Contrast Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07046416"
  },
  {
    "nct_id": "NCT07063355",
    "title": "Stripping Massage Technique and Post-isometric Relaxation",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 44,
    "conditions": [
      "Trapezius Myalgia"
    ],
    "interventions": [
      {
        "name": "Stripping Massage Technique:",
        "type": "OTHER"
      },
      {
        "name": "Post-Isometric Relaxation (PIR)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "The Perfect Physiotherapy Clinic, Muzaffargarh, Punjab Province, Pakistan"
    ],
    "start_date": "2025-07-24",
    "completion_date": "2025-10-20",
    "last_update": "2025-07-03",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07063355"
  },
  {
    "nct_id": "NCT06986694",
    "title": "Effects of Voodoo Flossing Technique in Knee Osteoarthritis Patients",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 42,
    "conditions": [
      "Knee Osteoarthritis",
      "Pain",
      "Range of Motion",
      "Physiotherapy"
    ],
    "interventions": [
      {
        "name": "Group A will receive Voodoo Flossing Technique along with aerobic and strengthening exercises & conventional physiotherapy protocol for Knee OA.",
        "type": "OTHER"
      },
      {
        "name": "Group B will receive aerobic and strength training and conventional physiotherapy protocol for knee OA only.",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Horizon Hospital, Lahore, Punjab Province, Pakistan"
    ],
    "start_date": "2025-06-12",
    "completion_date": "2025-12-01",
    "last_update": "2025-07-03",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06986694"
  },
  {
    "nct_id": "NCT07060430",
    "title": "Comparison of Kaltenborn Mobilization and Mobilization With Movement (MWM) in Wrist Hypomobility After Colle's Fracture",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Colles Fracture",
      "Hypomobility"
    ],
    "interventions": [
      {
        "name": "Kaltenborn Mobilization",
        "type": "PROCEDURE"
      },
      {
        "name": "Mulligan Mobilization with Movement",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Foundation University College of Physical Therapy, Islamabad, Pakistan"
    ],
    "start_date": "2024-09-15",
    "completion_date": "2025-06-30",
    "last_update": "2025-07-01",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07060430"
  },
  {
    "nct_id": "NCT07047846",
    "title": "Bowen Technique Versus Dynamic Soft Tissue Mobilization on Pain, Range of Motion and Functional Disability in Patients With Adhesive Capsulitis",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 72,
    "conditions": [
      "Adhesive Capsulitis"
    ],
    "interventions": [
      {
        "name": "Dynamic soft tissue mobilization",
        "type": "OTHER"
      },
      {
        "name": "Bowen Technique and 3 moves",
        "type": "OTHER"
      }
    ],
    "locations": [
      "UOL Teaching Hospital, Lahore, Punjab Province, Pakistan"
    ],
    "start_date": "2025-07-16",
    "completion_date": "2026-01-03",
    "last_update": "2025-07-01",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07047846"
  },
  {
    "nct_id": "NCT07045129",
    "title": "Thermal Therapies in the Treatment of Muscle Injuries",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 135,
    "conditions": [
      "Hamstring Injuries",
      "Hamstring Muscle Repair",
      "Hamstring Muscles",
      "Hamstring Rupture",
      "Muscle Tear"
    ],
    "interventions": [
      {
        "name": "Cold water immersion",
        "type": "OTHER"
      },
      {
        "name": "Hot water immersion",
        "type": "OTHER"
      },
      {
        "name": "Physiotherapy only",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Aspetar Orthopaedic and Sports Medicine Hospital, Doha, Qatar"
    ],
    "start_date": "2025-09",
    "completion_date": "2028-09",
    "last_update": "2025-06-22",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07045129"
  },
  {
    "nct_id": "NCT06986629",
    "title": "Effect of Photobiostimulation Versus Pulsed Electromagnetic Field on Quality of Life in Adults With Chronic Rhinosinusitis",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Photobiostimulation",
      "Pulsed Electromagnetic Filed",
      "Low Level Laser Therapy",
      "Chronic Rhinosinusitis (Diagnosis)",
      "Quality of Life"
    ],
    "interventions": [
      {
        "name": "pulsed electromagnetic therapy",
        "type": "DEVICE"
      },
      {
        "name": "Photobiostimulation",
        "type": "DEVICE"
      },
      {
        "name": "Self-sinus massage technique",
        "type": "OTHER"
      }
    ],
    "locations": [
      "out-patient clinic, faculty of physical therapy, October University for Modern Sciences and Arts, Cairo, Egypt"
    ],
    "start_date": "2025-02-01",
    "completion_date": "2025-08-01",
    "last_update": "2025-05-15",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06986629"
  },
  {
    "nct_id": "NCT05419726",
    "title": "Brown Adipose Tissue Activity in Response to Semaglutide Administered to Obese Subjects.",
    "status": "RECRUITING",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 20,
    "conditions": [
      "Obesity"
    ],
    "interventions": [
      {
        "name": "Semaglutide Injectable Product (not provided by the study)",
        "type": "DRUG"
      }
    ],
    "locations": [
      "UCLA Health, Los Angeles, California, United States"
    ],
    "start_date": "2023-02-01",
    "completion_date": "2026-02-01",
    "last_update": "2025-05-06",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05419726"
  },
  {
    "nct_id": "NCT05977894",
    "title": "Floatation Experience in Nurses and Physicians",
    "status": "ENROLLING_BY_INVITATION",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 50,
    "conditions": [
      "Burnout, Professional",
      "Negative Affect",
      "Positive Affect",
      "Wellbeing",
      "Burnout",
      "Psychological"
    ],
    "interventions": [
      {
        "name": "Reduced Environmental Stimulation Therapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "St. Elizabeth Youngstown Hospital, Youngstown, Ohio, United States"
    ],
    "start_date": "2023-10-28",
    "completion_date": "2026-05-05",
    "last_update": "2025-05-05",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05977894"
  },
  {
    "nct_id": "NCT04595006",
    "title": "Brown Fat Activation and Browning Efficiency Augmented by Chronic Cold and Nutraceuticals for Brown Adipose Tissue-mediated Effect Against Metabolic Syndrome (BEACON BEAMS Study)",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Energy Expenditure",
      "Obesity",
      "Brown Adipose Tissue"
    ],
    "interventions": [
      {
        "name": "Cold Stimulation (CS)",
        "type": "OTHER"
      },
      {
        "name": "Browning Nutraceutical (BN)",
        "type": "OTHER"
      },
      {
        "name": "Cold Stimulation and Browning Nutraceutical (CSBN)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Singapore Institute of Clinical Sciences, Singapore, Singapore"
    ],
    "start_date": "2021-01-15",
    "completion_date": "2028-08-16",
    "last_update": "2025-05-01",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04595006"
  },
  {
    "nct_id": "NCT05300971",
    "title": "Passive Heat Therapy for Lowering Systolic Blood Pressure and Improving Vascular Function in Mid-life and Older Adults",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 150,
    "conditions": [
      "Aging"
    ],
    "interventions": [
      {
        "name": "Heat therapy",
        "type": "OTHER"
      },
      {
        "name": "Thermoneutral water immersion",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Colorado Boulder, Boulder, Colorado, United States"
    ],
    "start_date": "2022-08-01",
    "completion_date": "2028-02-01",
    "last_update": "2025-04-23",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05300971"
  },
  {
    "nct_id": "NCT06941649",
    "title": "Efficacy of Two Approaches in Cervical Single-door Laminoplasty for Spinal Canal Enlargement",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 376,
    "conditions": [
      "Cervical Spondylotic Myelopathy"
    ],
    "interventions": [
      {
        "name": "Expansive open-door laminoplasty via intermuscular space approach",
        "type": "PROCEDURE"
      },
      {
        "name": "cervical single-door laminoplasty via the conventional approach",
        "type": "PROCEDURE"
      }
    ],
    "locations": [],
    "start_date": "2025-04-15",
    "completion_date": "2035-12-31",
    "last_update": "2025-04-22",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06941649"
  },
  {
    "nct_id": "NCT06767228",
    "title": "Effects of Reformer Pilates on Adolescents' Posture and Trunk Endurance",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 26,
    "conditions": [
      "Adolescent",
      "Healthy"
    ],
    "interventions": [
      {
        "name": "Reformer Pilates",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Trakya University, Edirne, İskender, Turkey (Türkiye)"
    ],
    "start_date": "2025-03-01",
    "completion_date": "2025-10-07",
    "last_update": "2025-04-08",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06767228"
  },
  {
    "nct_id": "NCT06920966",
    "title": "Recovery Optimization Intervention to Reduce the Risk of Injuries in Soccer Players",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 25,
    "conditions": [
      "Muscle Fatigue (C23.888.592.612.612)",
      "Athletic Injuries (C26.857.500.124)",
      "Recovery of Function (G11.427.698.620)",
      "Cryotherapy (E02.095.301.250)",
      "Thermotherapy (E02.095.301.750)",
      "Soccer (I03.450.642.845.750)",
      "Biomarkers (D23.050.301)",
      "Thermography (E01.370.350.700.750)",
      "Physical Fitness (G11.427.410.698)"
    ],
    "interventions": [
      {
        "name": "Cold Water Immersion (CWI)",
        "type": "OTHER"
      },
      {
        "name": "Hot water immersion (HWI)",
        "type": "OTHER"
      },
      {
        "name": "Thermography-Guided Immersion (TI)",
        "type": "OTHER"
      }
    ],
    "locations": [],
    "start_date": "2025-05-01",
    "completion_date": "2025-09-01",
    "last_update": "2025-04-02",
    "topics": [
      "cold-water-immersion",
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Cold-Water Immersion",
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06920966"
  },
  {
    "nct_id": "NCT06906146",
    "title": "Capacitive Resistive Electric Transfer Therapy on Muscle Recovery",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 50,
    "conditions": [
      "Muscle Oxygenation",
      "Lactate",
      "Anaerobic Exercise"
    ],
    "interventions": [
      {
        "name": "CRET therapy",
        "type": "DEVICE"
      },
      {
        "name": "Sham CRET Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [],
    "start_date": "2025-04-10",
    "completion_date": "2025-06-10",
    "last_update": "2025-03-28",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06906146"
  },
  {
    "nct_id": "NCT06819033",
    "title": "Effects of Photobiomodulation (PBM) on Pain After Presentation of Aphthous Ulcers in Pediatric Dental Patients",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE4"
    ],
    "enrollment": 30,
    "conditions": [
      "Aphthous Ulcer"
    ],
    "interventions": [
      {
        "name": "PBM Therapy",
        "type": "DEVICE"
      },
      {
        "name": "Maalox plus Benadryl",
        "type": "DRUG"
      }
    ],
    "locations": [
      "The University of Texas Health Science Center at Houston, Houston, Texas, United States"
    ],
    "start_date": "2025-03-10",
    "completion_date": "2026-02-28",
    "last_update": "2025-03-20",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06819033"
  },
  {
    "nct_id": "NCT06875466",
    "title": "Exploring the Health Benefits of Sauna Bathing",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 12,
    "conditions": [
      "Blood Pressure"
    ],
    "interventions": [
      {
        "name": "Sauna bathing",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "The Centre for Health, Tauranga, New Zealand"
    ],
    "start_date": "2025-03",
    "completion_date": "2025-07",
    "last_update": "2025-03-16",
    "topics": [
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06875466"
  },
  {
    "nct_id": "NCT06880484",
    "title": "Far-Infrared Socks for Neuropathic Pain and Nerve Function in Diabetic Patients",
    "status": "ENROLLING_BY_INVITATION",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 50,
    "conditions": [
      "Diabetic Peripheral Neuropathy (DPN)"
    ],
    "interventions": [
      {
        "name": "Far-Infrared Radiation (FIR) Socks",
        "type": "DEVICE"
      },
      {
        "name": "Placebo Socks",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Erciyes Üniversitesi, Talas, Kayseri, Turkey (Türkiye)"
    ],
    "start_date": "2025-02-02",
    "completion_date": "2026-06-30",
    "last_update": "2025-03-14",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06880484"
  },
  {
    "nct_id": "NCT06879405",
    "title": "The Effect of Labour Hopscotch Based Midwifery Care in Labor",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 100,
    "conditions": [
      "Labor Hopscotch"
    ],
    "interventions": [
      {
        "name": "The Labor Hopscotch",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Ataturk University, Erzurum, yakutiye, Turkey (Türkiye)"
    ],
    "start_date": "2023-12-01",
    "completion_date": "2025-12-01",
    "last_update": "2025-03-14",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06879405"
  },
  {
    "nct_id": "NCT06654167",
    "title": "Acute Effects of Cold Exposure on Cognitive Function",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Cognitive Function"
    ],
    "interventions": [
      {
        "name": "Low temperature (15℃) group",
        "type": "OTHER"
      },
      {
        "name": "Moderate temperature (22℃) group",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Department of Environmental Health, School of Public Health, Fudan University, Shanghai, Shanghai Municipality, China"
    ],
    "start_date": "2024-10-16",
    "completion_date": "2026-12-31",
    "last_update": "2025-02-25",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06654167"
  },
  {
    "nct_id": "NCT06804564",
    "title": "Cold Vs Warm Water Immersion for DOMS Recovery",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 52,
    "conditions": [
      "Muscle Soreness"
    ],
    "interventions": [
      {
        "name": "Cold Water Immersion (CWI)",
        "type": "OTHER"
      },
      {
        "name": "Hot Water Immersion (HWI)",
        "type": "OTHER"
      },
      {
        "name": "Simulated Laser Therapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Akademia Wychowania Fizycznego w Warszawie, Biała Podlaska, Lublin Voivodeship, Poland"
    ],
    "start_date": "2025-01-10",
    "completion_date": "2025-03-31",
    "last_update": "2025-02-07",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06804564"
  },
  {
    "nct_id": "NCT06769373",
    "title": "The Effects of Whirlpool and Contrast Bath in Patients with Complex Regional Pain Syndrome After Distal Radius Fracture",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Distal Radius Fracture",
      "Complex Regional Pain Syndrome Type I",
      "Complex Regional Pain Syndrome"
    ],
    "interventions": [
      {
        "name": "Whirlpool Bath",
        "type": "DEVICE"
      },
      {
        "name": "Contrast Bath",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Afyonkarahisar Health Sciences University, Afyonkarahisar, Afyonkarahisar, Turkey (Türkiye)"
    ],
    "start_date": "2025-01-31",
    "completion_date": "2025-06-15",
    "last_update": "2025-01-28",
    "topics": [
      "contrast-therapy"
    ],
    "topic_names": [
      "Contrast Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06769373"
  },
  {
    "nct_id": "NCT06788288",
    "title": "The Long-term Impact of Massage Chairs on Sleep Quality.",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 20,
    "conditions": [
      "Insomnia"
    ],
    "interventions": [
      {
        "name": "Massage Chair session",
        "type": "OTHER"
      },
      {
        "name": "Washout period",
        "type": "OTHER"
      }
    ],
    "locations": [
      "School of Physical Education, Sports and Dietetics, TEFAA, Trikala, Thessaly, Greece"
    ],
    "start_date": "2024-03-04",
    "completion_date": "2025-12-31",
    "last_update": "2025-01-22",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06788288"
  },
  {
    "nct_id": "NCT06785688",
    "title": "Energy Protector Aids for Improving the Lower Back Pain, Sports and Autonomic Nerve",
    "status": "ACTIVE_NOT_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 100,
    "conditions": [
      "the Effect of Infrared Rays Devices on Lower Back Pain"
    ],
    "interventions": [
      {
        "name": "Protective gear irradiated by infrared rays",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "National Taipei university of nursing and health science, Taipei, Taiwan"
    ],
    "start_date": "2023-05-31",
    "completion_date": "2025-01-31",
    "last_update": "2025-01-14",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06785688"
  },
  {
    "nct_id": "NCT05686525",
    "title": "Clinical Trial on the Effectiveness of TUMT Compared to PAE in Reducing Severe LUTS in Men with BPH",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 220,
    "conditions": [
      "Prostatic Hyperplasia",
      "Lower Urinary Tract Symptoms"
    ],
    "interventions": [
      {
        "name": "Transurethral Microwave Thermotherapy",
        "type": "PROCEDURE"
      },
      {
        "name": "Prostate Artery Embolisation",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Urological Research Unit, Rigshospitalet, Copenhagen, Copenhagen N, Denmark",
      "Department of Urology, Herlev-Gentofte Hospital, Gentofte Municipality, Hellerup, Denmark",
      "Zealand University Hospital, Roskilde, Denmark"
    ],
    "start_date": "2022-10-27",
    "completion_date": "2030-12",
    "last_update": "2025-01-10",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05686525"
  },
  {
    "nct_id": "NCT06739148",
    "title": "The Enhancement Effect of Low-Level Laser Therapy for Muscle Training with Combined NMES and BFR",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 44,
    "conditions": [
      "Blood Flow Restriction Therapy",
      "Neuromuscular Electrical Stimulation (NMES)",
      "Laser Therapy, Low-Level",
      "Muscle Strength"
    ],
    "interventions": [
      {
        "name": "Low Level Laser Therapy",
        "type": "DEVICE"
      },
      {
        "name": "blood flow restriction",
        "type": "DEVICE"
      },
      {
        "name": "Neuromuscular Electrical Stimulation",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "National Chen Kong University Hospital, Tainan, Tainan, Taiwan"
    ],
    "start_date": "2024-10-01",
    "completion_date": "2025-07-31",
    "last_update": "2024-12-16",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06739148"
  },
  {
    "nct_id": "NCT05850897",
    "title": "The Effect of Foot Massage on Anxiety, Pain and Comfort Level",
    "status": "ACTIVE_NOT_RECRUITING",
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      "NA"
    ],
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    "conditions": [
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    ],
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      {
        "name": "Masaj",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Nesibe Sultan ÇINAROĞLU, Niğde, Turkey (Türkiye)"
    ],
    "start_date": "2024-04-30",
    "completion_date": "2024-12-30",
    "last_update": "2024-12-10",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05850897"
  },
  {
    "nct_id": "NCT06717685",
    "title": "Efficacy of Adenosine as Compared to Verapamil in Paroxysmal Supraventricular Tachycardia (pSVT) Patients",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE3"
    ],
    "enrollment": 210,
    "conditions": [
      "Supraventricular Tachycardia (SVtach)"
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      {
        "name": "Adenosine",
        "type": "DRUG"
      },
      {
        "name": "Verapamil Injection",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Punjab Institute of Cardiology, Lahore, Punjab Province, Pakistan"
    ],
    "start_date": "2024-10-28",
    "completion_date": "2025-02-03",
    "last_update": "2024-12-09",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06717685"
  },
  {
    "nct_id": "NCT06667193",
    "title": "Cold Water Exposure's Effects on Physical and Mental Health",
    "status": "ENROLLING_BY_INVITATION",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 75,
    "conditions": [
      "Cold Exposure"
    ],
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      {
        "name": "Cold Water Immersion (CWI) - Cold Tub Immersion (CI)",
        "type": "OTHER"
      },
      {
        "name": "Cold Water Immersion (CWI) - Cold Shower (CS)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Northern Colorado, Greeley, Colorado, United States"
    ],
    "start_date": "2024-10-10",
    "completion_date": "2025-10-01",
    "last_update": "2024-10-29",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06667193"
  },
  {
    "nct_id": "NCT06645262",
    "title": "First-degree Ankle Sprains",
    "status": "RECRUITING",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 100,
    "conditions": [
      "Ankle Sprain 1St Degree"
    ],
    "interventions": [
      {
        "name": "Cryotherapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Rehabilitation Centre Život, Mostar, Bosnia and Herzegovina"
    ],
    "start_date": "2024-06-12",
    "completion_date": "2024-12-01",
    "last_update": "2024-10-14",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06645262"
  },
  {
    "nct_id": "NCT05701241",
    "title": "Continuing Somatostatin Analogues Upon Progression in Neuroendocrine Tumour pAtients",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE4"
    ],
    "enrollment": 270,
    "conditions": [
      "Gastroenteropancreatic Neuroendocrine Tumor"
    ],
    "interventions": [
      {
        "name": "Somatostatin analog",
        "type": "DRUG"
      }
    ],
    "locations": [
      "AZ Klina, Brasschaat, Antwerp, Belgium",
      "AZ Rivierenland, Rumst, Antwerp, Belgium",
      "Ghent University Hospital, Ghent, East Flanders, Belgium",
      "VITAZ, Sint-Niklaas, East-Flanders, Belgium",
      "University Hospital Leuven, Leuven, Flemish Brabant, Belgium",
      "Grand Hôpital de Charleroi, Charleroi, Hainaut, Belgium",
      "AZ Monica, Antwerp, Belgium",
      "GZA, Antwerp, Belgium"
    ],
    "start_date": "2023-06-28",
    "completion_date": "2034-04",
    "last_update": "2024-06-13",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05701241"
  },
  {
    "nct_id": "NCT06426082",
    "title": "Deciphering a Novel and Unique Brown Adipose Tissue Depot in Women",
    "status": "NOT_YET_RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Cardiometabolic Diseases"
    ],
    "interventions": [
      {
        "name": "Thermoneutral condition",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Cold condition",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Aerobic exercise condition",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Salbutamol",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Universidad de Almería, Almería, Spain"
    ],
    "start_date": "2024-11-01",
    "completion_date": "2026-08",
    "last_update": "2024-05-20",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06426082"
  },
  {
    "nct_id": "NCT05397262",
    "title": "Organ-preservative Therapy of Bladder Cancer With Radiotherapy or Radiochemotherapy Combined With Hyperthermia",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 1000,
    "conditions": [
      "Bladder Cancer"
    ],
    "interventions": [
      {
        "name": "Hyperthermia",
        "type": "OTHER"
      },
      {
        "name": "Radiotherapy",
        "type": "RADIATION"
      },
      {
        "name": "Chemotherapy 5-Fluorouracil",
        "type": "DRUG"
      },
      {
        "name": "Chemotherapy Cisplatin",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Dept. of Radiation Therapy, University Hospital Erlangen, Erlangen, Germany"
    ],
    "start_date": "2017-03-29",
    "completion_date": "2099-12-31",
    "last_update": "2024-05-08",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05397262"
  },
  {
    "nct_id": "NCT06399367",
    "title": "Investigation of Lipedema, Lymphedema and Vascular Malformations by Multispectral Optoacoustic Tomography (MSOT)",
    "status": "ENROLLING_BY_INVITATION",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 100,
    "conditions": [
      "Lipedema",
      "Lymphedema",
      "Vascular Malformations"
    ],
    "interventions": [
      {
        "name": "MSOT",
        "type": "DIAGNOSTIC_TEST"
      }
    ],
    "locations": [
      "Universitätsmedizin Göttingen, Göttingen, Lower Saxony, Germany"
    ],
    "start_date": "2024-08",
    "completion_date": "2028-12-01",
    "last_update": "2024-05-01",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06399367"
  },
  {
    "nct_id": "NCT06200285",
    "title": "International Registry of Accidental Hypothermia",
    "status": "RECRUITING",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 500,
    "conditions": [
      "Accidental Hypothermia"
    ],
    "interventions": [
      {
        "name": "Registry of patients with accidental hypothermia",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Medical University Innsbruck, Innsbruck, Austria",
      "Krankenhaus Barmherzige Brüder, Salzburg, Austria",
      "Rigshospitalet, Copenhagen, Denmark",
      "Klinik Immenstadt, Immenstadt im Allgäu, Germany",
      "ASST Bergamo Est, Bergamo, Italy",
      "EURAC Research, Bolzano, Italy",
      "Ospedale Santa Chiara, Trento, Italy",
      "Hokkaido Ohno Memorial Hospital, Hokkaido, Japan"
    ],
    "start_date": "2008-10-01",
    "completion_date": "2054-12",
    "last_update": "2023-12-27",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06200285"
  },
  {
    "nct_id": "NCT05177289",
    "title": "Photobiomodulation Therapy in the Prevention and Management of Chemotherapy-Induced Alopecia",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 72,
    "conditions": [
      "Chemotherapy-induced Alopecia"
    ],
    "interventions": [
      {
        "name": "Theradome® LH80 pro",
        "type": "DEVICE"
      },
      {
        "name": "Scalp cooling",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Jessa Hospital, Hasselt, Limburg, Belgium"
    ],
    "start_date": "2022-02-28",
    "completion_date": "2030-01",
    "last_update": "2023-09-28",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05177289"
  },
  {
    "nct_id": "NCT04979078",
    "title": "Photobiomodulation Therapy in the Management of Hand-foot Syndrome and Hand-foot Skin Reaction",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Hand-foot Syndrome",
      "Hand-foot Skin Reaction"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation therapy (PBMT)",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Hasselt University, Hasselt, Limburg, Belgium",
      "Jessa Ziekenhuis VZW, Hasselt, Limburg, Belgium"
    ],
    "start_date": "2022-01-12",
    "completion_date": "2029-08",
    "last_update": "2023-06-15",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04979078"
  },
  {
    "nct_id": "NCT05752682",
    "title": "Global Approach to Faint and Falls",
    "status": "RECRUITING",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 340,
    "conditions": [
      "Syncope",
      "Fall"
    ],
    "interventions": [
      {
        "name": "Diagnostic pathway",
        "type": "DIAGNOSTIC_TEST"
      }
    ],
    "locations": [
      "IRCCS Istituto Auxologico Italiano, Milan, MI, Italy"
    ],
    "start_date": "2020-03-01",
    "completion_date": "2026-12-31",
    "last_update": "2023-03-14",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05752682"
  },
  {
    "nct_id": "NCT05069363",
    "title": "Whole-Body Photobiomodulation and Chronic Pain Trial",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 20,
    "conditions": [
      "Chronic Pain"
    ],
    "interventions": [
      {
        "name": "Whole-Body Photobiomodulation Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Sandwell and West Birmingham NHS Trust, Birmingham, United Kingdom"
    ],
    "start_date": "2022-01-12",
    "completion_date": "2023-09",
    "last_update": "2022-06-26",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05069363"
  },
  {
    "nct_id": "NCT04363541",
    "title": "Local Thermotherapy for Patients With Mild-to-moderate COVID-19",
    "status": "RECRUITING",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 274,
    "conditions": [
      "COVID-19",
      "Thermotherapy"
    ],
    "interventions": [
      {
        "name": "Electric pad for human external pain therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Hospital Dr. Ángel Leaño, Guadalajara, Jalisco, Mexico",
      "Hospital Regional de Alta Especialidad \"Dr. Juan Graham Casasus\", Villahermosa, Tabasco, Mexico",
      "Unidad Temporal Movil COVID-19 Autódromo Hermanos Rodríguez IMSS, Mexico City, Mexico"
    ],
    "start_date": "2020-08-27",
    "completion_date": "2022-06",
    "last_update": "2020-11-03",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04363541"
  },
  {
    "nct_id": "NCT07111156",
    "title": "A Clinical Study to Test the Safety and Effectiveness of Pinorox® for Improving Visible Signs of Facial Aging Such as Wrinkles, Fine Lines, and Dark Spots.",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 81,
    "conditions": [
      "Fine Lines",
      "Wrinkles",
      "Facial Sign of Aging"
    ],
    "interventions": [
      {
        "name": "Topical Cream containing 0.1% Pinorox®",
        "type": "OTHER"
      },
      {
        "name": "Topical Cream containing 1% Pinorox®",
        "type": "OTHER"
      },
      {
        "name": "Placebo (Base Cream)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "NovoBliss Research Private Limited, Ahmedabad, Gujarat, India"
    ],
    "start_date": "2025-10-16",
    "completion_date": "2026-02-17",
    "last_update": "2026-08-04",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07111156"
  },
  {
    "nct_id": "NCT04268524",
    "title": "Randomised Clinical Trial in Treatment Modalities for Cutaneous Leishmaniasis Caused by Leishmania Tropica, in Pakistan",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE3"
    ],
    "enrollment": 645,
    "conditions": [
      "Old World Cutaneous Leishmaniasis"
    ],
    "interventions": [
      {
        "name": "drug: miltefosine with thermotherapy",
        "type": "COMBINATION_PRODUCT"
      }
    ],
    "locations": [
      "Bolan Medical Complex Hospital, Quetta, Balochistan, Pakistan",
      "Kuchlak Primary Health Care Centre (MCH), Kuchlak, Pakistan, Quetta, Balochistan, Pakistan",
      "Shaheed Mohtarma Benazir Bhutto General Hospital, Quetta, Balochistan, Pakistan"
    ],
    "start_date": "2022-10-07",
    "completion_date": "2026-06-19",
    "last_update": "2026-07-29",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04268524"
  },
  {
    "nct_id": "NCT07728422",
    "title": "Effects of Ozone Therapy on Muscle Damage",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 32,
    "conditions": [
      "Ozone Therapy",
      "Muscle Damage",
      "Oxidative Stress",
      "Recovery"
    ],
    "interventions": [
      {
        "name": "Autohemotherapy",
        "type": "OTHER"
      },
      {
        "name": "Ozone Sauna Therapy",
        "type": "OTHER"
      },
      {
        "name": "Ozonated Lavender Oil Massage",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Inonu University, Malatya, Malatya, Turkey (Türkiye)"
    ],
    "start_date": "2024-10-04",
    "completion_date": "2025-02-20",
    "last_update": "2026-07-21",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07728422"
  },
  {
    "nct_id": "NCT07724444",
    "title": "Laser Therapy Versus Ozone Therapy for Oral Mucositis in Patients With Cancer",
    "status": "COMPLETED",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 40,
    "conditions": [
      "Oral Mucositis"
    ],
    "interventions": [
      {
        "name": "Laser Therapy",
        "type": "DEVICE"
      },
      {
        "name": "Ozone therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Paediatrics - University of Pavia, Pavia, Lombardy, Italy"
    ],
    "start_date": "2024-09-25",
    "completion_date": "2025-09-29",
    "last_update": "2026-07-20",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07724444"
  },
  {
    "nct_id": "NCT06938256",
    "title": "Suboccipital Muscle Inhibition Technique vs Rocabado Exercises on Cervicogenic Headache",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Cervicogenic Headache"
    ],
    "interventions": [
      {
        "name": "Suboccipital Muscle Inhibition",
        "type": "OTHER"
      },
      {
        "name": "Rocabado 6x6 Exercises",
        "type": "OTHER"
      }
    ],
    "locations": [
      "National Institute of Rehabilitation and Medicine, Islamabad, Pakistan"
    ],
    "start_date": "2025-01-03",
    "completion_date": "2025-07-15",
    "last_update": "2026-07-17",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06938256"
  },
  {
    "nct_id": "NCT07712289",
    "title": "Comparative Analysis Between Textured Insoles and Roods Technique Affecting Balance in DNP.",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 44,
    "conditions": [
      "Diabetic Neuropathy",
      "Diabetes"
    ],
    "interventions": [
      {
        "name": "Roods Facilitatory Technique",
        "type": "OTHER"
      },
      {
        "name": "Textured Insoles",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "The University of Faisalabad, Faisalābad, Punjab Province, Pakistan"
    ],
    "start_date": "2025-03-04",
    "completion_date": "2025-05-26",
    "last_update": "2026-07-14",
    "topics": [
      "contrast-therapy"
    ],
    "topic_names": [
      "Contrast Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07712289"
  },
  {
    "nct_id": "NCT06698237",
    "title": "The Effects of Cold-water Immersion on Exercise Performance Recovery and Postprandial Plasma Aminoacidemia",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 12,
    "conditions": [
      "Sport Recovery",
      "Aminoacidemia",
      "Cold-water Immersion"
    ],
    "interventions": [
      {
        "name": "immediate cold-water immersion",
        "type": "OTHER"
      },
      {
        "name": "delayed cold-water immersion",
        "type": "OTHER"
      },
      {
        "name": "immediate thermoneutral water immersion",
        "type": "OTHER"
      }
    ],
    "locations": [
      "McGill University, Montreal, Quebec, Canada"
    ],
    "start_date": "2024-12-20",
    "completion_date": "2025-11-03",
    "last_update": "2026-07-12",
    "topics": [
      "cold-water-immersion",
      "exercise-recovery"
    ],
    "topic_names": [
      "Cold-Water Immersion",
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06698237"
  },
  {
    "nct_id": "NCT07169461",
    "title": "Effectiveness of Low Level Light Therapy and Intense Pulse Light on Mite Count as Adjuntive Therapies in Demodex Blepharitis Using Artificial Intelligent Program (Ai-Demodex)",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 88,
    "conditions": [
      "Demodex Blepharitis",
      "Meibomian Gland Dysfunction (MGD)"
    ],
    "interventions": [
      {
        "name": "The blue MY MASK-E",
        "type": "DEVICE"
      },
      {
        "name": "IPL",
        "type": "DEVICE"
      },
      {
        "name": "Mechanical with pharmacological treatment",
        "type": "PROCEDURE"
      },
      {
        "name": "ShamIPL",
        "type": "DEVICE"
      },
      {
        "name": "ShamLLLT",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Chulalongkorn University, Pathum Wan, Bangkok, Thailand"
    ],
    "start_date": "2025-02-01",
    "completion_date": "2025-05-30",
    "last_update": "2026-07-10",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07169461"
  },
  {
    "nct_id": "NCT06565468",
    "title": "The Effect of Cold Water Immersion on Recovery and Performance in NCAA Division I Athletes",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 75,
    "conditions": [
      "Recovery, Physiological",
      "Athletic Performance"
    ],
    "interventions": [
      {
        "name": "Cold water immersion pool.",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "UCLA Orthopedics, Los Angeles, California, United States"
    ],
    "start_date": "2024-09-15",
    "completion_date": "2025-06-30",
    "last_update": "2026-07-09",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06565468"
  },
  {
    "nct_id": "NCT04660552",
    "title": "Transcranial Photobiomodulation for Reducing Autism Symptoms in Children",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 34,
    "conditions": [
      "Autism Spectrum Disorder"
    ],
    "interventions": [
      {
        "name": "Cognilum TM: Light Treatment Condition",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Dr. Steingold Psychology PC, Brooklyn, New York, United States",
      "Dr. Steingold Psychology PC, New York, New York, United States"
    ],
    "start_date": "2020-11-15",
    "completion_date": "2023-12-30",
    "last_update": "2026-06-12",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04660552"
  },
  {
    "nct_id": "NCT06670365",
    "title": "Enhancing Heat Resiliency in Older Adults During Indoor Overheating Via Heat Acclimation by Warm Water Immersion",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 16,
    "conditions": [
      "Hyperthermia",
      "Thermoregulation",
      "Aging",
      "Heat Acclimation and Thermotolerance"
    ],
    "interventions": [
      {
        "name": "Heat acclimation by warm-water immersion",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Ottawa, Ottawa, Ontario, Canada"
    ],
    "start_date": "2024-11-11",
    "completion_date": "2026-05-18",
    "last_update": "2026-06-09",
    "topics": [
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06670365"
  },
  {
    "nct_id": "NCT01772706",
    "title": "Laser Mucite ORL : Effectiveness of Laser Therapy for Mucositis Induced by a Radio-chemotherapy in Head and Neck Cancer",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 97,
    "conditions": [
      "Oral Squamous Cell Carcinoma",
      "Squamous Cell Carcinoma of Oropharynx",
      "Squamous Cell Carcinoma of Hypopharynx",
      "Oral Mucositis"
    ],
    "interventions": [
      {
        "name": "low level laser therapy",
        "type": "PROCEDURE"
      },
      {
        "name": "placebo (laser low level energy nonfunctional)",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Institut de Cancerologie de l'Ouest Paul Papin, Angers, France",
      "Centre Guillaume le Conquérant, Le Havre, France",
      "Hôpital La Pitié Salpêtrière, Paris, France",
      "Centre hospitalier universitaire La Milétrie, Poitiers, France",
      "Centre Jean Godinot, Reims, France",
      "Clinique Armoricaine de Radiologie, Saint-Brieuc, France"
    ],
    "start_date": "2008-10-30",
    "completion_date": "2020-03",
    "last_update": "2026-06-05",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01772706"
  },
  {
    "nct_id": "NCT07613814",
    "title": "Development of a Management Model for Hyperemesis in Pregnant Women Through the \"Vibratory Emesis Massage\"",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 240,
    "conditions": [
      "Hyperemesis Gravidarum"
    ],
    "interventions": [
      {
        "name": "Vibratory Emesis Massage",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Prof. Dr. Chairuddin Panusunan Lubis Hospital, University of North Sumatra, Medan, North Sumatra, Indonesia"
    ],
    "start_date": "2026-04-10",
    "completion_date": "2026-04-15",
    "last_update": "2026-05-28",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07613814"
  },
  {
    "nct_id": "NCT06348225",
    "title": "Post-exercise Hot Water Immersion to Improve Overnight Blood Pressure",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 20,
    "conditions": [
      "Elevated Blood Pressure"
    ],
    "interventions": [
      {
        "name": "Exercise",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Heat Therapy",
        "type": "OTHER"
      },
      {
        "name": "Sham leg bath",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Providence College, Providence, Rhode Island, United States"
    ],
    "start_date": "2024-07-01",
    "completion_date": "2026-04-30",
    "last_update": "2026-05-28",
    "topics": [
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06348225"
  },
  {
    "nct_id": "NCT05989217",
    "title": "Conservative Therapies in the Treatment of Temporomandibular Disorders",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 160,
    "conditions": [
      "Temporomandibular Joint Disorders",
      "Temporomandibular Joint Pain",
      "Splints",
      "Photobiomodulation"
    ],
    "interventions": [
      {
        "name": "Occlusal Splint",
        "type": "DEVICE"
      },
      {
        "name": "Laser Therapy",
        "type": "RADIATION"
      },
      {
        "name": "Acupuncture Laser Therapy",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "Universidade Federal de Alfenas, Alfenas, Minas Gerais, Brazil"
    ],
    "start_date": "2023-03-01",
    "completion_date": "2025-01-30",
    "last_update": "2026-05-20",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05989217"
  },
  {
    "nct_id": "NCT07293195",
    "title": "Adjunctive Effects of Heat vs Contrast Therapy With Otago Exercises on Patellofemoral Pain Syndrome",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Patello Femoral Pain Syndrome",
      "Patello Femoral Syndrome",
      "Patellofemoral Disorder"
    ],
    "interventions": [
      {
        "name": "Heat therapy+Otago exercise program",
        "type": "OTHER"
      },
      {
        "name": "Contrast therapy+ Otago exercise program",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Ghurki Trust Teaching Hospital, Lahore, Punjab Province, Pakistan"
    ],
    "start_date": "2025-12-10",
    "completion_date": "2026-05-12",
    "last_update": "2026-05-18",
    "topics": [
      "contrast-therapy",
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Contrast Therapy",
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07293195"
  },
  {
    "nct_id": "NCT06380179",
    "title": "Photomedicine Project 14: PBMT for Performance Enhancement in SOF",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 29,
    "conditions": [
      "Photobiomodulation Therapy",
      "Photomedicine",
      "Low-Level Laser Therapy",
      "Performance Enhancement",
      "Quadriceps",
      "Special Operations Readiness"
    ],
    "interventions": [
      {
        "name": "THOR3 training + Photobiomodulation Therapy (PBMT)",
        "type": "DEVICE"
      },
      {
        "name": "THOR3 training + sham PBMT",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Joint Base Lewis-McChord, Joint Base Lewis McChord, Washington, United States"
    ],
    "start_date": "2025-01-23",
    "completion_date": "2026-03-02",
    "last_update": "2026-05-18",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06380179"
  },
  {
    "nct_id": "NCT07588841",
    "title": "Evaluation of Low Energy Level Laser Biostimulation at Different Energy Densities in the Treatment of Temporomandibular Joint Irregularities: A Retrospective Study",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 100,
    "conditions": [
      "Myalgia of Mastication Muscle"
    ],
    "interventions": [
      {
        "name": "Low Level Laser Therapy",
        "type": "OTHER"
      },
      {
        "name": "Dietary Supplement",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Karadeniz Technical University, Trabzon, Trabzon, Turkey (Türkiye)"
    ],
    "start_date": "2022-09-03",
    "completion_date": "2024-12-24",
    "last_update": "2026-05-13",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07588841"
  },
  {
    "nct_id": "NCT05708976",
    "title": "HypErthermia as an Additional Treatment for the Biology and Experience of Depression: Study 2",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Major Depressive Disorder",
      "Depression"
    ],
    "interventions": [
      {
        "name": "Cognitive Behavioral Therapy (CBT)",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Active Whole-Body Hyperthermia (Active WBH)",
        "type": "DEVICE"
      },
      {
        "name": "Sham Whole-Body Hyperthermia (Sham WBH)",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "University of California San Francisco, San Francisco, California, United States"
    ],
    "start_date": "2023-02-15",
    "completion_date": "2024-09-30",
    "last_update": "2026-05-11",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05708976"
  },
  {
    "nct_id": "NCT05041361",
    "title": "HypErthermia as an Additional Treatment for the Biology and Experience of Depression",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 16,
    "conditions": [
      "Major Depressive Disorder"
    ],
    "interventions": [
      {
        "name": "Cognitive Behavioral Therapy (CBT)",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Whole-Body Hyperthermia (WBH)",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "University of California San Francisco, San Francisco, California, United States"
    ],
    "start_date": "2021-10-11",
    "completion_date": "2023-03-01",
    "last_update": "2026-05-11",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05041361"
  },
  {
    "nct_id": "NCT07570199",
    "title": "THE EFFECTS OF FUNCTIONAL ELECTRICAL STIMULATION-ASSISTED BICYCLE ERGOMETRY IN PATIENTS DIAGNOSED WITH COMPLEX REGIONAL PAIN SYNDROME.(CRPS)",
    "status": "COMPLETED",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 40,
    "conditions": [
      "Complex Regional Pain Syndrome I of Upper Limb",
      "Pain"
    ],
    "interventions": [
      {
        "name": "Functional Electrical Stimulation",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Ankara Bilkent City Hospital, Ankara, Çankaya, Turkey (Türkiye)"
    ],
    "start_date": "2024-07-15",
    "completion_date": "2026-02-15",
    "last_update": "2026-04-30",
    "topics": [
      "contrast-therapy"
    ],
    "topic_names": [
      "Contrast Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07570199"
  },
  {
    "nct_id": "NCT06784531",
    "title": "The Influence of Race and MitoQ Supplementation on Skin Blood Flow in the Cold",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 26,
    "conditions": [
      "Cold Exposure"
    ],
    "interventions": [
      {
        "name": "Mitoquinone mesylate (MitoQ)",
        "type": "DIETARY_SUPPLEMENT"
      },
      {
        "name": "Placebo",
        "type": "DIETARY_SUPPLEMENT"
      },
      {
        "name": "Cold Water Hand Immersion",
        "type": "OTHER"
      },
      {
        "name": "Cold Air Exposure",
        "type": "OTHER"
      }
    ],
    "locations": [
      "U.S. Army Research Institute of Environmental Medicine, Natick, Massachusetts, United States"
    ],
    "start_date": "2024-09-16",
    "completion_date": "2025-10-28",
    "last_update": "2026-04-29",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06784531"
  },
  {
    "nct_id": "NCT06626048",
    "title": "Optimizing an Integrated Mind and Body Treatment for Insomnia: The SLEEPS Study",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 10,
    "conditions": [
      "Insomnia Disorder"
    ],
    "interventions": [
      {
        "name": "Cognitive Behavioral Therapy for Insomnia",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Passive Body Heating (PBH)",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "University of California San Francisco, San Francisco, California, United States"
    ],
    "start_date": "2025-02-07",
    "completion_date": "2026-01-22",
    "last_update": "2026-04-27",
    "topics": [
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06626048"
  },
  {
    "nct_id": "NCT07060131",
    "title": "Observe the Effects of Far Infrared Eye Masks on Acupoints Around the Eyes in Patients With Dry Eye Syndrome",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 31,
    "conditions": [
      "Dry Eye Disease (DED)"
    ],
    "interventions": [
      {
        "name": "Far Infrared Eye Masks",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "China Medical University Hospital, Taichung, North Dist, Taiwan"
    ],
    "start_date": "2024-03-21",
    "completion_date": "2025-12-10",
    "last_update": "2026-04-26",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07060131"
  },
  {
    "nct_id": "NCT07537465",
    "title": "Mirror Therapy for Complex Regional Pain Syndrome in Stroke Patients",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Stroke",
      "Complex Regional Pain Syndrome I (CRPS I)",
      "Mirror Therapy"
    ],
    "interventions": [
      {
        "name": "Mirror Therapy",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Sham Mirror Therapy",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Başakşehir Çam&Sakura City Hospital, Istanbul, Turkey (Türkiye)"
    ],
    "start_date": "2022-10-01",
    "completion_date": "2023-10-15",
    "last_update": "2026-04-16",
    "topics": [
      "contrast-therapy"
    ],
    "topic_names": [
      "Contrast Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07537465"
  },
  {
    "nct_id": "NCT04316702",
    "title": "Hyperbaric Oxygen Therapy Compared to Pharmaceutical in Fibromyalgia With Emotional Trauma",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 48,
    "conditions": [
      "Fibromyalgia",
      "Emotional Trauma"
    ],
    "interventions": [
      {
        "name": "Hyperbaric oxygen therapy (HBOT) treatment",
        "type": "DEVICE"
      },
      {
        "name": "Cymbalta / Lyrica - Drug treatment",
        "type": "DRUG"
      }
    ],
    "locations": [
      "hyperbaric center Asaf harofe medical center, Rishon LeZiyyon, Israel"
    ],
    "start_date": "2020-03-01",
    "completion_date": "2023-11-30",
    "last_update": "2026-04-16",
    "topics": [
      "cold-water-immersion",
      "exercise-recovery"
    ],
    "topic_names": [
      "Cold-Water Immersion",
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04316702"
  },
  {
    "nct_id": "NCT05627141",
    "title": "Photobiomodulation, Cryotherapy Combined With Compression, and Massage for Recovery",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Laser",
      "Muscle; Fatigue, Heart",
      "Muscle Damage"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation; Cryotherapy, Massage",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Filipe Abdalla, Campo Grande, Mato Grosso do Sul, Brazil"
    ],
    "start_date": "2022-03-01",
    "completion_date": "2023-07-01",
    "last_update": "2026-04-12",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05627141"
  },
  {
    "nct_id": "NCT07512479",
    "title": "Effectiveness of Hatha Yoga and From Feeling to Seeing the Body (FSB) in Female Adolescents and Young Adults With Eating Disorders.",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 54,
    "conditions": [
      "Body Image",
      "Eating Disorders",
      "Anorexia Nervosa",
      "Bulimia Nervosa"
    ],
    "interventions": [
      {
        "name": "Hatha Yoga Group (Y)",
        "type": "BEHAVIORAL"
      },
      {
        "name": "From Feeling to Seeing the Body Group (FSB)",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Control Group (C)",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Centro Provinciale per i Disturbi dell'Alimentazione, Treviso, Italy"
    ],
    "start_date": "2025-03-10",
    "completion_date": "2026-01-27",
    "last_update": "2026-04-01",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07512479"
  },
  {
    "nct_id": "NCT07504718",
    "title": "The Effect of Cold Exposure on Physiological Markers",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 41,
    "conditions": [
      "Healthy Adult Participants"
    ],
    "interventions": [
      {
        "name": "Cold water immerssion",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Lithuanian Sports University, Kaunas, Lithuania"
    ],
    "start_date": "2013-05-13",
    "completion_date": "2018-05-06",
    "last_update": "2026-04-01",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07504718"
  },
  {
    "nct_id": "NCT07503977",
    "title": "Acute Physiological Effects of Full-Body Far-Infrared Emitting Textiles on Young Road Cyclists",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
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      "NA"
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      "Athletes",
      "Cyclists"
    ],
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      {
        "name": "FIR",
        "type": "DEVICE"
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      {
        "name": "Placebo",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "University of Urbino, Urbino, The Marches, Italy"
    ],
    "start_date": "2025-04-15",
    "completion_date": "2025-06-25",
    "last_update": "2026-03-26",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07503977"
  },
  {
    "nct_id": "NCT06843824",
    "title": "A Graphene Far-infrared Intervention Study of Cognitive Status in Older Adults",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
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    "conditions": [
      "Mild Cognitive Impairment (MCI)",
      "Subjective Cognitive Decrease (SCD)",
      "Alzheimer's Disease(AD)",
      "Depression/Anxiety Symptoms"
    ],
    "interventions": [
      {
        "name": "a custom-made graphene therapy cap",
        "type": "DEVICE"
      },
      {
        "name": "A regular cap that generates heat",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Institute of Psychology, Chinese Academy of Sciences, Beijing, Beijing Municipality, China"
    ],
    "start_date": "2025-03-10",
    "completion_date": "2025-05-30",
    "last_update": "2026-03-24",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06843824"
  },
  {
    "nct_id": "NCT06813690",
    "title": "Effects of Immediate and Delayed Repeated Cold Exposure After Physical Exertion",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 48,
    "conditions": [
      "Delayed Onset Muscle Soreness (DOMS)",
      "Inflammation",
      "Muscle Pain",
      "Muscle Damage"
    ],
    "interventions": [
      {
        "name": "Cold Therapy with Axanova Cold Hot Pearls Maxi Pack",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "University of Applied Sciences and Arts of Southern Switzerland (SUPSI), Landquart, Switzerland"
    ],
    "start_date": "2025-03-17",
    "completion_date": "2025-10-16",
    "last_update": "2026-03-03",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06813690"
  },
  {
    "nct_id": "NCT06192329",
    "title": "Hot Water Therapy for the Treatment of Menopause-related Hot Flashes",
    "status": "WITHDRAWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 0,
    "conditions": [
      "Menopause",
      "Menopause Related Conditions",
      "Menopause Syndrome"
    ],
    "interventions": [
      {
        "name": "Hot water therapy",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Warm water immersion",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Hybl Sports Medicine and Performance Center, Colorado Springs, Colorado, United States"
    ],
    "start_date": "2025-01-01",
    "completion_date": "2025-11-19",
    "last_update": "2026-02-23",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06192329"
  },
  {
    "nct_id": "NCT02899221",
    "title": "Hyperthermia and High Dose Rate Radiation Therapy in Treating Patients With Recurrent Prostate Cancer After Radiation",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 3,
    "conditions": [
      "Recurrent Prostate Carcinoma"
    ],
    "interventions": [
      {
        "name": "High-Dose Rate Brachytherapy",
        "type": "RADIATION"
      },
      {
        "name": "Hyperthermia Treatment",
        "type": "PROCEDURE"
      },
      {
        "name": "Laboratory Biomarker Analysis",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, Pennsylvania, United States"
    ],
    "start_date": "2017-03-21",
    "completion_date": "2025-10-29",
    "last_update": "2026-02-18",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02899221"
  },
  {
    "nct_id": "NCT04971408",
    "title": "Impact of Passive Heat on Metabolic, Inflammatory and Vascular Health in Persons With Spinal Cord Injury",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 10,
    "conditions": [
      "Spinal Cord Injury",
      "Chronic Inflammation",
      "Glucose Metabolism",
      "Endothelial Function"
    ],
    "interventions": [
      {
        "name": "passive heat stress",
        "type": "OTHER"
      },
      {
        "name": "Control",
        "type": "OTHER"
      }
    ],
    "locations": [
      "South Texas Health Care System, San Antonio, TX, San Antonio, Texas, United States"
    ],
    "start_date": "2022-07-01",
    "completion_date": "2024-06-30",
    "last_update": "2026-02-13",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04971408"
  },
  {
    "nct_id": "NCT04797390",
    "title": "A Study Evaluating an Advanced Pneumatic Compression Device Versus Usual Care for Treatment of Head and Neck Lymphedema",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 236,
    "conditions": [
      "Lymphedema",
      "Lymphedema of Face",
      "Lymphedema, Secondary",
      "Lymphedema Due to Radiation",
      "Lymphedema; Surgical"
    ],
    "interventions": [
      {
        "name": "Advanced Pneumatic Compression Device (APCD)",
        "type": "DEVICE"
      },
      {
        "name": "Usual Care",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Alabama, Birmingham, Alabama, United States",
      "Rush University Medical Center, Chicago, Illinois, United States",
      "University of Louisville, Louisville, Kentucky, United States",
      "Johns Hopkins University, Baltimore, Maryland, United States",
      "University of Michigan, Ann Arbor, Michigan, United States",
      "Karmanos Cancer Institute, Detroit, Michigan, United States",
      "Richmond University Medical Center, Staten Island, New York, United States",
      "Montefiore Medical Center, The Bronx, New York, United States"
    ],
    "start_date": "2021-09-23",
    "completion_date": "2024-12-03",
    "last_update": "2026-02-09",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04797390"
  },
  {
    "nct_id": "NCT07389707",
    "title": "The Effect of Using Hand Massage Stimulation Techniques on Pain and Comfort in Pregnant Women Experiencing Lumbar Pain",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 74,
    "conditions": [
      "Pregnancy Related"
    ],
    "interventions": [
      {
        "name": "seed therapy (su-jok)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Inonu University, Malatya, Battalgazi̇, Turkey (Türkiye)"
    ],
    "start_date": "2024-10-15",
    "completion_date": "2025-01-15",
    "last_update": "2026-02-03",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07389707"
  },
  {
    "nct_id": "NCT06795841",
    "title": "Photobiomodulation Therapy Versus Integrated Myofascial Release Therapy Techniques In Patients With COVID-19 With Follow-Up Telerehabilitation",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 102,
    "conditions": [
      "COVID 19 Disease"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation",
        "type": "RADIATION"
      },
      {
        "name": "Myofascial release therapy",
        "type": "PROCEDURE"
      },
      {
        "name": "traditional chest physiotherapy",
        "type": "DEVICE"
      },
      {
        "name": "telerehabilitation",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Faculty of Physical Therapy , Beni-Suef University, Banī Suwayf, Egypt"
    ],
    "start_date": "2020-06-01",
    "completion_date": "2020-12-31",
    "last_update": "2026-01-23",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06795841"
  },
  {
    "nct_id": "NCT04725513",
    "title": "Pilot Investigation to Evaluate Effectiveness of Shockwave Therapy, Photobiomodulation and Physical Therapy in the Management of Non-insertional Achilles Tendinopathy",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 46,
    "conditions": [
      "Achilles Tendinopathy"
    ],
    "interventions": [
      {
        "name": "Shockwave Therapy",
        "type": "DEVICE"
      },
      {
        "name": "Photobiomodulation Therapy",
        "type": "DEVICE"
      },
      {
        "name": "Physical Therapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Spaulding Hospital Cambridge, Cambridge, Massachusetts, United States"
    ],
    "start_date": "2022-08-29",
    "completion_date": "2024-10-01",
    "last_update": "2026-01-09",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04725513"
  },
  {
    "nct_id": "NCT06893679",
    "title": "Effects of Qigong Sensory Training on Sensory Modulation and Behavior in Children With Autism",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 26,
    "conditions": [
      "Autism"
    ],
    "interventions": [
      {
        "name": "Qigong sensory training",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Nishtar Medical University, Multan, Multan Khurd, Punjab Province, Pakistan"
    ],
    "start_date": "2025-03-17",
    "completion_date": "2025-09-17",
    "last_update": "2025-12-29",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06893679"
  },
  {
    "nct_id": "NCT06539858",
    "title": "Investigation of the Effect of Massage Application on Functional Status and Depression in Postpartum Mothers",
    "status": "COMPLETED",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 28,
    "conditions": [
      "Depression, Post-Partum",
      "Massage",
      "Functional Status"
    ],
    "interventions": [
      {
        "name": "massage",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Yalova, Yalova, Turkey (Türkiye)"
    ],
    "start_date": "2024-05-10",
    "completion_date": "2025-03-30",
    "last_update": "2025-12-12",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06539858"
  },
  {
    "nct_id": "NCT07303192",
    "title": "Effect of i-PRF and LLLT on Free Gingival Graft Shrinkage",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 48,
    "conditions": [
      "Graft Shrinkage",
      "Gingival Recession, Localized"
    ],
    "interventions": [
      {
        "name": "Free Gingival Graft (FGG)",
        "type": "PROCEDURE"
      },
      {
        "name": "Injectable Platelet-Rich Fibrin (i-PRF)",
        "type": "BIOLOGICAL"
      },
      {
        "name": "Low-Level Laser Therapy (LLLT)",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Turkey (Türkiye)"
    ],
    "start_date": "2024-07-01",
    "completion_date": "2025-08-30",
    "last_update": "2025-12-11",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07303192"
  },
  {
    "nct_id": "NCT07265440",
    "title": "Effect of New Specialized Technique Using Effleurage Massage on Striae Gravidarum",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 42,
    "conditions": [
      "Striae Gravidarum"
    ],
    "interventions": [
      {
        "name": "New specialized technique using effleurage massage",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Outpatient Clinics, Faculty of Physical Therapy, Kafrelsheikh University, Egypt, Kafr ash Shaykh, Kafr el-Sheikh Governorate, Egypt"
    ],
    "start_date": "2024-10-09",
    "completion_date": "2025-05-30",
    "last_update": "2025-12-02",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07265440"
  },
  {
    "nct_id": "NCT07244718",
    "title": "Investigation of The Effect of Progressive Muscle Relaxation Technique in Sedentary Obese Women",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 20,
    "conditions": [
      "Progressive Muscle Relaxation Technique"
    ],
    "interventions": [
      {
        "name": "Control",
        "type": "OTHER"
      },
      {
        "name": "Music-Assisted Progressive Muscle Relaxation",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Pamukkale University, Denizli, Denizli, Turkey (Türkiye)"
    ],
    "start_date": "2024-02-01",
    "completion_date": "2025-01-31",
    "last_update": "2025-12-02",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07244718"
  },
  {
    "nct_id": "NCT07262697",
    "title": "Laser Therapy for Patients With Nonspecific Neck Pain",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Neck Pain",
      "Non Specific Neck Pain"
    ],
    "interventions": [
      {
        "name": "HILT",
        "type": "OTHER"
      },
      {
        "name": "LLLT",
        "type": "OTHER"
      },
      {
        "name": "CONTROL",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Mohammed Hegazy, Al Kharj, Saudi Arabia"
    ],
    "start_date": "2023-03-01",
    "completion_date": "2024-04-01",
    "last_update": "2025-11-30",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07262697"
  },
  {
    "nct_id": "NCT07274293",
    "title": "EVALUATION OF THE TOLERABILITY AND BIOMEDICAL POTENTIAL OF A GARMENT CONTAINING PRINTED CERAMICS IN MUSCULAR PAIN",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 50,
    "conditions": [
      "Cervical Pain",
      "Lumbar Pain",
      "Muscular",
      "Chronic Pain (Back / Neck)",
      "Pain Management"
    ],
    "interventions": [
      {
        "name": "DZero",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "DAIRI, Alessandria, 15121, Alessandria, Italy"
    ],
    "start_date": "2025-05-06",
    "completion_date": "2025-10-13",
    "last_update": "2025-11-27",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07274293"
  },
  {
    "nct_id": "NCT07184190",
    "title": "Effects of Trancutaneous Auriculotemporal Nerve Stimulation",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 12,
    "conditions": [
      "Healthy"
    ],
    "interventions": [
      {
        "name": "Trancutaneous Auriculotemporal Nerve Stimulation",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Universidad del Gran Rosario, Rosario, Santa Fe Province, Argentina"
    ],
    "start_date": "2025-09-26",
    "completion_date": "2025-11-14",
    "last_update": "2025-11-20",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07184190"
  },
  {
    "nct_id": "NCT06788041",
    "title": "EFFECT OF HAMMAM EXPERIENCE ON GENERAL HEALTH AND PERCEIVED WELL-BEING",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 22,
    "conditions": [
      "Chronic Stress",
      "Wellness",
      "General Health"
    ],
    "interventions": [
      {
        "name": "Hamman experience",
        "type": "OTHER"
      },
      {
        "name": "Massage",
        "type": "OTHER"
      },
      {
        "name": "Placebo Comparator",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Granada, Granada, Spain"
    ],
    "start_date": "2024-09-01",
    "completion_date": "2025-11-15",
    "last_update": "2025-11-15",
    "topics": [
      "massage-therapy",
      "sauna-heat-therapy",
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Massage Therapy",
      "Sauna & Heat Therapy",
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06788041"
  },
  {
    "nct_id": "NCT02220426",
    "title": "Hyperpolarized Xenon-129 Magnetic Resonance Imaging and Spectroscopy of Brown Fat: Healthy Adult Volunteer Pilot Study",
    "status": "TERMINATED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 17,
    "conditions": [
      "Obesity"
    ],
    "interventions": [
      {
        "name": "Xenon",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Biomedical Research Imaging Center, Chapel Hill, North Carolina, United States"
    ],
    "start_date": "2015-09-01",
    "completion_date": "2016-07-01",
    "last_update": "2025-11-12",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02220426"
  },
  {
    "nct_id": "NCT07209891",
    "title": "COMPARISON STUY OF KINESIOTAPE AND LOW-LEVEL LASER THERAPY ON HYPERTROPHIC SCAR",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Hypertrophic Scar",
      "Burn Scar (Post-burn)",
      "Burns"
    ],
    "interventions": [
      {
        "name": "Kinesio Tape",
        "type": "DEVICE"
      },
      {
        "name": "Low-Level Laser Therapy (LLLT), 905-nm pulsed Ga-As",
        "type": "DEVICE"
      },
      {
        "name": "Standardized Scar Care (concomitant for all arms)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Huda Badr Abd Elhamed, Cairo, Egypt"
    ],
    "start_date": "2023-10-05",
    "completion_date": "2024-12-30",
    "last_update": "2025-09-29",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07209891"
  },
  {
    "nct_id": "NCT06868329",
    "title": "Virtual Reality Vased Exercises and Hyperlordosis in Low Back Pain",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 50,
    "conditions": [
      "Hyperlordosis"
    ],
    "interventions": [
      {
        "name": "Superficial moist heat",
        "type": "OTHER"
      },
      {
        "name": "Hamstring and back muscles stretching",
        "type": "OTHER"
      },
      {
        "name": "posterior pelvic tilting exercises regular procedures",
        "type": "OTHER"
      },
      {
        "name": "Postural correction with lumbar stabilization using TBed",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Hail, Ha'il, Ha'il Region, Saudi Arabia"
    ],
    "start_date": "2025-03-06",
    "completion_date": "2025-08-15",
    "last_update": "2025-09-29",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06868329"
  },
  {
    "nct_id": "NCT04902924",
    "title": "Cold and Warm Water for Performance Recovery",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Healthy"
    ],
    "interventions": [
      {
        "name": "repeated cold water therapy",
        "type": "BEHAVIORAL"
      },
      {
        "name": "repeated warm water therapy",
        "type": "BEHAVIORAL"
      },
      {
        "name": "control",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Applied Sciences and Arts of Southern Switzerland, Landquart, Kanton Graubünden, Switzerland"
    ],
    "start_date": "2021-10-01",
    "completion_date": "2022-05-01",
    "last_update": "2025-09-25",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04902924"
  },
  {
    "nct_id": "NCT06602921",
    "title": "The Effects of Nitrate, Caffeine, and Cold Exposure on Cardiovascular Function.",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 24,
    "conditions": [
      "Nitrate",
      "Caffeine",
      "Cold Exposure"
    ],
    "interventions": [
      {
        "name": "TruBeet inorganic beetroot juice",
        "type": "DIETARY_SUPPLEMENT"
      },
      {
        "name": "Caffeine",
        "type": "DIETARY_SUPPLEMENT"
      },
      {
        "name": "Cold pressor test",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Loughborough University, Loughborough, United Kingdom"
    ],
    "start_date": "2023-12-05",
    "completion_date": "2025-04-01",
    "last_update": "2025-09-05",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06602921"
  },
  {
    "nct_id": "NCT00186888",
    "title": "Study of Treatment for Patients With Cancer of the Eye -Retinoblastoma",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE3"
    ],
    "enrollment": 107,
    "conditions": [
      "Retinoblastoma",
      "Retinal Neoplasm"
    ],
    "interventions": [
      {
        "name": "Enucleation",
        "type": "PROCEDURE"
      },
      {
        "name": "Vincristine, Carboplatin",
        "type": "DRUG"
      },
      {
        "name": "Focal Therapies",
        "type": "PROCEDURE"
      },
      {
        "name": "External Beam Radiation",
        "type": "RADIATION"
      },
      {
        "name": "Vincristine and Topotecan",
        "type": "DRUG"
      },
      {
        "name": "Vincristine + Carboplatin + Etoposide",
        "type": "DRUG"
      },
      {
        "name": "vincristine, cyclophosphamide, and doxorubicin",
        "type": "DRUG"
      },
      {
        "name": "Vincristine, Carboplatin and Etoposide",
        "type": "DRUG"
      },
      {
        "name": "Periocular carboplatin",
        "type": "PROCEDURE"
      },
      {
        "name": "G-CSF",
        "type": "OTHER"
      }
    ],
    "locations": [
      "St. Jude Children's Research Hospital, Memphis, Tennessee, United States"
    ],
    "start_date": "2005-04-07",
    "completion_date": "2024-11-12",
    "last_update": "2025-09-02",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00186888"
  },
  {
    "nct_id": "NCT04628910",
    "title": "Examining the Differential Effects of Traditional Float-REST and Dry Float on Subjective and Objective Health Outcomes",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 20,
    "conditions": [
      "Sleep Quality"
    ],
    "interventions": [
      {
        "name": "Simulated Flotation Therapy",
        "type": "OTHER"
      },
      {
        "name": "Traditional Float-REST Therapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Rockefeller Neuroscience Institute at West Virginia University, Morgantown, West Virginia, United States"
    ],
    "start_date": "2020-07-01",
    "completion_date": "2023-10-31",
    "last_update": "2025-08-21",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04628910"
  },
  {
    "nct_id": "NCT02874040",
    "title": "Endoresection of the Tumor Scar or Transpupillary Thermotherapy for the Treatment of Large Uveal Melanomas (Endoresection-Laser)",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 87,
    "conditions": [
      "Uveal Melanoma",
      "Melanoma, Uveal"
    ],
    "interventions": [
      {
        "name": "Endoresection",
        "type": "PROCEDURE"
      },
      {
        "name": "Laser diode",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Institut Curie, Paris, France"
    ],
    "start_date": "2013-04-19",
    "completion_date": "2024-10-24",
    "last_update": "2025-08-07",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02874040"
  },
  {
    "nct_id": "NCT07118553",
    "title": "Factors Affecting Premenstrual Syndrome",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 27,
    "conditions": [
      "Premenstrual Syndrome"
    ],
    "interventions": [
      {
        "name": "classic facial massage",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Trabzon Unversity, Trabzon, Tonya, Turkey (Türkiye)"
    ],
    "start_date": "2025-05-14",
    "completion_date": "2025-06-20",
    "last_update": "2025-08-05",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07118553"
  },
  {
    "nct_id": "NCT05622747",
    "title": "Acute Passive Heating in Healthy Older Adults",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 23,
    "conditions": [
      "Aging"
    ],
    "interventions": [
      {
        "name": "Passive heating",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Spinnaker Building, Portsmouth, Hampshire, United Kingdom"
    ],
    "start_date": "2023-05-23",
    "completion_date": "2025-07-24",
    "last_update": "2025-08-01",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05622747"
  },
  {
    "nct_id": "NCT05618197",
    "title": "Chronic Passive Heating in Healthy Older Adults",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 19,
    "conditions": [
      "Aging"
    ],
    "interventions": [
      {
        "name": "Passive heating",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Spinnaker Building, Portsmouth, Hampshire, United Kingdom"
    ],
    "start_date": "2023-05-23",
    "completion_date": "2025-06-06",
    "last_update": "2025-08-01",
    "topics": [
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05618197"
  },
  {
    "nct_id": "NCT07089459",
    "title": "Low Level Laser Therapy Versus Short Wave Diathermy in Patients With Anterior Cruciate Ligament Tear",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 72,
    "conditions": [
      "Anterior Cruciate Ligament (ACL) Tear"
    ],
    "interventions": [
      {
        "name": "Low-Level Laser Therapy (LLLT)",
        "type": "DEVICE"
      },
      {
        "name": "Shortwave therapy",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "The University of Lahore Teaching Hospital, Lahore, Pakistan"
    ],
    "start_date": "2024-10-15",
    "completion_date": "2025-07-15",
    "last_update": "2025-07-30",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07089459"
  },
  {
    "nct_id": "NCT06349616",
    "title": "Cooling Strategies for Older Adults in the Heat",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 12,
    "conditions": [
      "Aging"
    ],
    "interventions": [
      {
        "name": "Intermittent cold-water hand and forearm immersion",
        "type": "OTHER"
      },
      {
        "name": "No intermittent cold-water hand and forearm immersion",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Noll Laboratory, University Park, Pennsylvania, United States"
    ],
    "start_date": "2024-05-01",
    "completion_date": "2025-07-21",
    "last_update": "2025-07-21",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06349616"
  },
  {
    "nct_id": "NCT07089472",
    "title": "Dry Needling Versus Cyriax Technique on Pain, Paraesthesia and Functional Disability in Patients With Chronic Low Back Pain",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 80,
    "conditions": [
      "Meralgia Paresthetica",
      "Chronic Low-back Pain (cLBP)"
    ],
    "interventions": [
      {
        "name": "Dry Needling Therapy",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Cyriax Technique",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "The University of Lahore Teaching Hospital, Lahore, Pakistan"
    ],
    "start_date": "2024-11-25",
    "completion_date": "2025-07-19",
    "last_update": "2025-07-20",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07089472"
  },
  {
    "nct_id": "NCT05256966",
    "title": "Firefighter Soot, Sauna, and Sweat Excretion Pilot Study",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 86,
    "conditions": [
      "Cancer"
    ],
    "interventions": [
      {
        "name": "Sauna (steam)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "HealthPartners Institute, Minneapolis, Minnesota, United States"
    ],
    "start_date": "2021-11-01",
    "completion_date": "2024-05-30",
    "last_update": "2025-07-14",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05256966"
  },
  {
    "nct_id": "NCT07072780",
    "title": "Effectiveness of a Novel Low-level Laser Therapy Protocol in Managing Breast Cancer-Related Lymphedema",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 46,
    "conditions": [
      "Breast Cancer"
    ],
    "interventions": [
      {
        "name": "Low-Level Laser Therapy (904 nm)",
        "type": "DEVICE"
      },
      {
        "name": "Low-Level Laser Therapy (650 nm)",
        "type": "DEVICE"
      },
      {
        "name": "Sham Laser Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Pusan National University Hospital, Busan, Seo-Gu, South Korea"
    ],
    "start_date": "2023-11-23",
    "completion_date": "2024-12-31",
    "last_update": "2025-07-09",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07072780"
  },
  {
    "nct_id": "NCT07062913",
    "title": "Contrast Compression Therapy for Post-Stroke Complex Regional Pain Syndrome",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 72,
    "conditions": [
      "Stroke",
      "Complex Regional Pain Syndrome",
      "Hemiplegia"
    ],
    "interventions": [
      {
        "name": "Conventional Rehabilitation",
        "type": "PROCEDURE"
      },
      {
        "name": "Contrast Compression Therapy",
        "type": "DEVICE"
      },
      {
        "name": "Conventional Rehabilitation",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Ankara City Hospital, Ankara, Turkey (Türkiye)"
    ],
    "start_date": "2021-11-01",
    "completion_date": "2023-01-09",
    "last_update": "2025-07-03",
    "topics": [
      "contrast-therapy"
    ],
    "topic_names": [
      "Contrast Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07062913"
  },
  {
    "nct_id": "NCT06630637",
    "title": "Monitoring Intermittent Fasting for Human Optimization Using Wearable Technology: An N-of-1 Study",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 1,
    "conditions": [
      "Intermittent Fasting",
      "Healthy",
      "Digital Health"
    ],
    "interventions": [
      {
        "name": "Glucose-Ketone Index (GKI) monitoring",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Continuous Glucose Monitoring (CGM)",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Digital dynamometer",
        "type": "OTHER"
      },
      {
        "name": "Wearables",
        "type": "DEVICE"
      },
      {
        "name": "Blood tests",
        "type": "DIAGNOSTIC_TEST"
      },
      {
        "name": "Stool tests",
        "type": "DIAGNOSTIC_TEST"
      },
      {
        "name": "Saliva tests",
        "type": "DIAGNOSTIC_TEST"
      },
      {
        "name": "Fitness intervention",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Cold & heat intervention",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Airofit",
        "type": "DEVICE"
      },
      {
        "name": "18h fasting",
        "type": "BEHAVIORAL"
      },
      {
        "name": "48h fasting",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "The Institute for Digital Medicine (WisDM), Singapore, Singapore, Singapore"
    ],
    "start_date": "2024-10-07",
    "completion_date": "2025-07-02",
    "last_update": "2025-07-03",
    "topics": [
      "exercise-recovery",
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Exercise Recovery",
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06630637"
  },
  {
    "nct_id": "NCT05751785",
    "title": "Shockwave, Photobiomodulation, and Physical Therapy for Achilles Tendinopathy",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 48,
    "conditions": [
      "Achilles Tendinopathy"
    ],
    "interventions": [
      {
        "name": "Physical Therapy",
        "type": "OTHER"
      },
      {
        "name": "Shockwave Therapy",
        "type": "DEVICE"
      },
      {
        "name": "Photobiomodulation Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Madigan Army Medical Center, Tacoma, Washington, United States"
    ],
    "start_date": "2023-02-13",
    "completion_date": "2024-11-14",
    "last_update": "2025-07-01",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05751785"
  },
  {
    "nct_id": "NCT03858179",
    "title": "Effects of Photobiomodulation Therapy in Strength Training and Detraining in Humans",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Muscle Strength"
    ],
    "interventions": [
      {
        "name": "PBMT",
        "type": "DEVICE"
      },
      {
        "name": "Placebo",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Laboratory of Phototherapy and Innovative Technologies in Health, São Paulo, São Paulo, Brazil"
    ],
    "start_date": "2019-03-25",
    "completion_date": "2022-05-13",
    "last_update": "2025-06-23",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03858179"
  },
  {
    "nct_id": "NCT07029048",
    "title": "Oxidative Stress and Cognitive Dysfunction After COVID-19",
    "status": "COMPLETED",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 45,
    "conditions": [
      "COVID 19",
      "Oxydative Stress",
      "Cognitive Impairments"
    ],
    "interventions": [
      {
        "name": "Standard Post-COVID Rehabilitation Program",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Karaganda Medical University, Astana, Kazakhstan"
    ],
    "start_date": "2021-03-01",
    "completion_date": "2023-06-01",
    "last_update": "2025-06-19",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07029048"
  },
  {
    "nct_id": "NCT05506514",
    "title": "Heat Therapy to Accelerate Muscle Recovery",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 34,
    "conditions": [
      "Muscle Damage"
    ],
    "interventions": [
      {
        "name": "Water immersion",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Aspetar sport medicine hospital, Doha, Baladiyat ad Dawhah, Qatar"
    ],
    "start_date": "2022-07-14",
    "completion_date": "2024-04-27",
    "last_update": "2025-06-12",
    "topics": [
      "cold-water-immersion",
      "exercise-recovery",
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Cold-Water Immersion",
      "Exercise Recovery",
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05506514"
  },
  {
    "nct_id": "NCT05857124",
    "title": "A Study Evaluating the Efficacy of the Vielight Neuro RX Gamma in the Treatment of Post COVID-19 Cognitive Impairment",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 36,
    "conditions": [
      "Post COVID-19 Cognitive Impairment"
    ],
    "interventions": [
      {
        "name": "Vielight Neuro RX Gamma active device",
        "type": "DEVICE"
      },
      {
        "name": "Vielight Neuro RX Gamma sham device",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Ascada Research, Fullerton, California, United States"
    ],
    "start_date": "2023-04-01",
    "completion_date": "2025-01-16",
    "last_update": "2025-06-10",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05857124"
  },
  {
    "nct_id": "NCT07020507",
    "title": "Exploratory Study to Evaluate the Efficacy of the Cosmetic Product RV3895A on Re-epidermised Scars Following Burns and Surgical Stitches in Adults, Adolescents and Children Over a 6-month Follow-up Period",
    "status": "TERMINATED",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 35,
    "conditions": [
      "Skin Scars",
      "Post-burn Scars",
      "Post-surgical-stitches Scars"
    ],
    "interventions": [
      {
        "name": "Product gel RV3895A",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Clinique de Rééducation et de Réadaptation Fonctionnelle du Docteur Jean Ster, Lamalou-les-Bains, France"
    ],
    "start_date": "2021-11-23",
    "completion_date": "2023-10-03",
    "last_update": "2025-06-04",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT07020507"
  },
  {
    "nct_id": "NCT06903000",
    "title": "Effects of IASTM and Vibration Therapy in Cervical Disc Herniation",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 57,
    "conditions": [
      "Intervertebral Disc Displacement",
      "Neck Pain"
    ],
    "interventions": [
      {
        "name": "a percussion massage gun",
        "type": "DEVICE"
      },
      {
        "name": "specially designed stainless-steel instruments",
        "type": "DEVICE"
      },
      {
        "name": "Conventional Exercise Group (Control)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Emre Dansuk, Istanbul, Beykoz, Turkey (Türkiye)"
    ],
    "start_date": "2025-03-28",
    "completion_date": "2025-06-01",
    "last_update": "2025-05-31",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06903000"
  },
  {
    "nct_id": "NCT03983707",
    "title": "A Evaluation of the Utilisation, Effectiveness and Safety of Purastat® in the Management of Gastrointestinal Bleeding",
    "status": "COMPLETED",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 379,
    "conditions": [
      "Gastrointestinal Bleeding",
      "Delayed Bleeding"
    ],
    "interventions": [
      {
        "name": "Purastat®",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Queen Alexandra Hospital, Portsmouth, Hampshire, United Kingdom"
    ],
    "start_date": "2019-01-23",
    "completion_date": "2021-10-31",
    "last_update": "2025-05-27",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03983707"
  },
  {
    "nct_id": "NCT06992050",
    "title": "Comparative Evaluation of the Thermal Protection Provided by Submarine Rescue Suits: Half Suit Versus Full Suit",
    "status": "COMPLETED",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 20,
    "conditions": [
      "Cold Exposure, Hypothermia, Thermal Insulation, Immersion Suits, Submarine Evacuation"
    ],
    "interventions": [
      {
        "name": "Submariner suit",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Israel Naval Medical Institute, Haifa, Israel"
    ],
    "start_date": "2018-03-01",
    "completion_date": "2024-12-01",
    "last_update": "2025-05-19",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06992050"
  },
  {
    "nct_id": "NCT05763381",
    "title": "Low-Level Laser Therapy for Plantar Fasciitis",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 71,
    "conditions": [
      "Plantar Fascitis"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation Therapy (PBMT)",
        "type": "DEVICE"
      },
      {
        "name": "Sham-Photobiomodualtion Therapy (Sham-PBMT)",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Madigan Army Medical Center, Tacoma, Washington, United States"
    ],
    "start_date": "2022-08-11",
    "completion_date": "2024-10-31",
    "last_update": "2025-05-15",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05763381"
  },
  {
    "nct_id": "NCT00762437",
    "title": "Non-Invasive Cooling of Fat Cells",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 175,
    "conditions": [
      "Reduction of Unwanted Fat"
    ],
    "interventions": [
      {
        "name": "Zeltiq Dermal Cooling Device",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Investigational Site, Sacramento, California, United States",
      "Investigational Site, San Diego, California, United States",
      "Investigational Site, Washington D.C., District of Columbia, United States",
      "Investigational Site, Miami, Florida, United States",
      "Investigational Site, Chicago, Illinois, United States",
      "Investigational Site, Baltimore, Maryland, United States",
      "Investigational Site, Boston, Massachusetts, United States",
      "Investigational Site, Minneapolis, Minnesota, United States"
    ],
    "start_date": "2008-01",
    "completion_date": "2009-12-18",
    "last_update": "2025-05-07",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00762437"
  },
  {
    "nct_id": "NCT04689009",
    "title": "Leg Ulcers Standards of Care Enhancement",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 83,
    "conditions": [
      "Venous Leg Ulcer",
      "Mixed Leg Ulcer"
    ],
    "interventions": [
      {
        "name": "EmoLED",
        "type": "DEVICE"
      },
      {
        "name": "current Standards Of Care",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Ospedale Briolini, ASST Bergamo EST, Gazzaniga, Bergamo, Italy",
      "Ospedale Felice Lotti, Pontedera, Pisa, Italy",
      "Geriatrics Unit, Presidio Ospedaliero di Rete San Bassiano, ULSS 7 Pedemontana, Bassano del Grappa, Vicenza, Italy",
      "Dermatology Unit AOU Policlinico Sant'Orsola - Malpighi, Bologna, Italy",
      "Dermatology Unit, Azienda Ospedaliero Universitaria Pisana, Stabilimento di S. Chiara, Pisa, Italy"
    ],
    "start_date": "2019-05-14",
    "completion_date": "2024-02-29",
    "last_update": "2025-04-24",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04689009"
  },
  {
    "nct_id": "NCT05963555",
    "title": "PBM or Dry Float Therapy on Sleep Quality in Middle-aged and Elderly",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 15,
    "conditions": [
      "Sleep Quality"
    ],
    "interventions": [
      {
        "name": "NovoThor",
        "type": "DEVICE"
      },
      {
        "name": "VieLight",
        "type": "DEVICE"
      },
      {
        "name": "ZeroBody",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "WVU Rockefeller Neuroscience Institute, Morgantown, West Virginia, United States"
    ],
    "start_date": "2023-07-31",
    "completion_date": "2025-03-25",
    "last_update": "2025-04-21",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05963555"
  },
  {
    "nct_id": "NCT02392078",
    "title": "Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System",
    "status": "COMPLETED",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 1153,
    "conditions": [
      "Metastatic Brain Tumor",
      "Primary Brain Tumor",
      "Epileptic/Seizure Foci",
      "Movement Disorders"
    ],
    "interventions": [
      {
        "name": "NeuroBlate System",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Barrow Neurological Institute at Dignity Health St. Joseph's Hospital & Medical Center, Phoenix, Arizona, United States",
      "University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States",
      "University of California, San Diego, La Jolla, California, United States",
      "Children's Hospital of Orange County, Orange, California, United States",
      "Yale University School of Medicine, New Haven, Connecticut, United States",
      "Advent Health Orlando, Orlando, Florida, United States",
      "Johns Hopkins All Children's Hospital, St. Petersburg, Florida, United States",
      "The Cleveland Clinic Florida, Weston, Florida, United States"
    ],
    "start_date": "2015-10",
    "completion_date": "2023-09-30",
    "last_update": "2025-04-07",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02392078"
  },
  {
    "nct_id": "NCT05093179",
    "title": "The Effect of Deep Tissue Massage on Respiratory Parameters in Healthy People",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Spirometry",
      "Massage"
    ],
    "interventions": [
      {
        "name": "Deep tissue massage",
        "type": "PROCEDURE"
      },
      {
        "name": "Classic massage",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Institute of Physiotherapy Jagiellonian University Medical College, Krakow, Poland"
    ],
    "start_date": "2019-02-01",
    "completion_date": "2019-03-31",
    "last_update": "2025-03-18",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05093179"
  },
  {
    "nct_id": "NCT05736133",
    "title": "Determining the Impact of a Physiotherapist-Led Primary Care Model for Hip and Knee Pain - A Pilot Trial",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 205,
    "conditions": [
      "Hip Osteoarthritis",
      "Knee Osteoarthritis"
    ],
    "interventions": [
      {
        "name": "Physiotherapist-led primary care model for hip and knee pain",
        "type": "OTHER"
      },
      {
        "name": "Usual physician-led primary care model for hip and knee pain",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Queen's University, Kingston, Ontario, Canada"
    ],
    "start_date": "2023-10-02",
    "completion_date": "2025-01-17",
    "last_update": "2025-03-17",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05736133"
  },
  {
    "nct_id": "NCT02665507",
    "title": "Light Therapy for the Treatment of Back Pain in Pilots (LLL&Pilots)",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE2",
      "PHASE3"
    ],
    "enrollment": 42,
    "conditions": [
      "Back Pain"
    ],
    "interventions": [
      {
        "name": "GaAlAs 808nm laser",
        "type": "DEVICE"
      },
      {
        "name": "Sham",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Aviation Medicine Unit, Ramat Gan, Israel"
    ],
    "start_date": "2018-03-01",
    "completion_date": "2024-07-03",
    "last_update": "2025-03-10",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02665507"
  },
  {
    "nct_id": "NCT06675149",
    "title": "Diacutaneus Fibrolysis on Tempromandibular Joint Pain and Trismus Post Oral Surgery",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Temporomandibular Pain"
    ],
    "interventions": [
      {
        "name": "Diacutaneus fibrolysis",
        "type": "DEVICE"
      },
      {
        "name": "Transcutaneous electrical nerve stimulation",
        "type": "DEVICE"
      },
      {
        "name": "Massage",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Cairo University, Giza, Egypt"
    ],
    "start_date": "2024-08-20",
    "completion_date": "2025-02-27",
    "last_update": "2025-02-27",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06675149"
  },
  {
    "nct_id": "NCT03188835",
    "title": "Effects of Fructose/Glucose-rich Diet on Brown Fat in Healthy Subjects (GB7)",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 15,
    "conditions": [
      "Type2 Diabetes"
    ],
    "interventions": [
      {
        "name": "Diet",
        "type": "DIETARY_SUPPLEMENT"
      },
      {
        "name": "cold exposure",
        "type": "OTHER"
      },
      {
        "name": "18FDG",
        "type": "RADIATION"
      },
      {
        "name": "11C-acetate",
        "type": "RADIATION"
      },
      {
        "name": "[3-3H]-glucose",
        "type": "RADIATION"
      },
      {
        "name": "[U-13C]-palmitate",
        "type": "OTHER"
      },
      {
        "name": "2H-Glycerol",
        "type": "OTHER"
      },
      {
        "name": "MRI/MRS",
        "type": "DEVICE"
      },
      {
        "name": "Electromyogram (EMG)",
        "type": "DEVICE"
      },
      {
        "name": "DXA",
        "type": "DEVICE"
      },
      {
        "name": "Indirect calorimetry",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Centre de recherche du CHUS, Sherbrooke, Quebec, Canada"
    ],
    "start_date": "2017-05-23",
    "completion_date": "2021-04-30",
    "last_update": "2025-01-22",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03188835"
  },
  {
    "nct_id": "NCT06778577",
    "title": "The Efficacy of Suprascapular Nerve Radiofrequency and Intra-articular Steroid Injection in Frozen Shoulder Treatment",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 80,
    "conditions": [
      "Frozen Shoulder",
      "Radiofrequency Ablation Treatment",
      "Intra-articular Injection"
    ],
    "interventions": [
      {
        "name": "intra-articular corticosteroid injection (IACI) group",
        "type": "OTHER"
      },
      {
        "name": "suprascapular nerve radiofrequency group (SCNRFT)",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Ankara University, Faculty of Medicine, Department of Anesthesiology and Reanimation, Department of Algology, Ankara, Turkey (Türkiye)"
    ],
    "start_date": "2021-08-15",
    "completion_date": "2022-10-20",
    "last_update": "2025-01-12",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06778577"
  },
  {
    "nct_id": "NCT06769321",
    "title": "Automatic Thermomechanical Massage Bed for Acute Pain Relief for Chronic Nonspecific Low Back Pain",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Chronic Non-specific Low Back Pain"
    ],
    "interventions": [
      {
        "name": "Automatic Thermo-mechanical Massage Bed",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "The Center for Discovery and Innovation, New York, New York, United States"
    ],
    "start_date": "2024-06-05",
    "completion_date": "2024-07-27",
    "last_update": "2025-01-09",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06769321"
  },
  {
    "nct_id": "NCT06764732",
    "title": "Socket Seal Surgery",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 45,
    "conditions": [
      "Socket Sealing"
    ],
    "interventions": [
      {
        "name": "bioactive glass",
        "type": "BIOLOGICAL"
      },
      {
        "name": "bioactive glass graft and PBM irradiation",
        "type": "RADIATION"
      },
      {
        "name": "Platelet rich fibrin",
        "type": "BIOLOGICAL"
      }
    ],
    "locations": [
      ", Faculty of Oral and Dental Medicine, Delta University for Science and Technology (DU), Dakahlia, Egypt, Dakahlia, Egypt"
    ],
    "start_date": "2022-11-10",
    "completion_date": "2024-02-10",
    "last_update": "2025-01-03",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06764732"
  },
  {
    "nct_id": "NCT06761950",
    "title": "Photobiomodulation Therapy on Pain and Range of Motion Following Flexor Tendon Repair",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 44,
    "conditions": [
      "Photobiomodulation Therapy",
      "Low Level Laser Therapy",
      "Flexor Tendon Rupture",
      "Flexor Tendon Repair"
    ],
    "interventions": [
      {
        "name": "Low Level laser therapy",
        "type": "DEVICE"
      },
      {
        "name": "Placebo low level laser therapy",
        "type": "DEVICE"
      },
      {
        "name": "medical treatment",
        "type": "OTHER"
      },
      {
        "name": "physical therapy program",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Cairo university hospitals, Cairo, Egypt"
    ],
    "start_date": "2024-08-01",
    "completion_date": "2024-12-25",
    "last_update": "2024-12-31",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06761950"
  },
  {
    "nct_id": "NCT06748287",
    "title": "A Clinical Comparison of FDA-Cleared Photobiomodulation Devices for the Treatment of Alopecia",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "EARLY_PHASE1"
    ],
    "enrollment": 104,
    "conditions": [
      "Alopecia"
    ],
    "interventions": [
      {
        "name": "iGrow Hair Growth System",
        "type": "DEVICE"
      },
      {
        "name": "Capillus352",
        "type": "DEVICE"
      },
      {
        "name": "HairMax Ultima 12 Lasercomb",
        "type": "DEVICE"
      },
      {
        "name": "HairMax Laserband 82",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "University of Minnesota, Minneapolis, Minnesota, United States"
    ],
    "start_date": "2017-01-03",
    "completion_date": "2023-02-01",
    "last_update": "2024-12-20",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06748287"
  },
  {
    "nct_id": "NCT06745089",
    "title": "Treatment Effect of Intense Pulsed Light and Thermal Pulsation Therapy on Meibomian Gland Dysfunction-associated Dry Eye Disease: a Randomized Trial",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 45,
    "conditions": [
      "Dry Eye Disease (DED)",
      "Meibomian Gland Dysfunction"
    ],
    "interventions": [
      {
        "name": "Intense pulsed light",
        "type": "DEVICE"
      },
      {
        "name": "thermal pulsation therapy",
        "type": "DEVICE"
      },
      {
        "name": "Ocular lubricant",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Institute of Biophotonics, National Yang Ming Chiao Tung University, Taipei, Taiwan"
    ],
    "start_date": "2022-07-13",
    "completion_date": "2024-03-10",
    "last_update": "2024-12-17",
    "topics": [
      "massage-therapy",
      "photobiomodulation"
    ],
    "topic_names": [
      "Massage Therapy",
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06745089"
  },
  {
    "nct_id": "NCT05704322",
    "title": "The Effectiveness of the Wim Hof Method in People with Spinal Cord Injury",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Spinal Cord Injuries"
    ],
    "interventions": [
      {
        "name": "Wim Hof Methode",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Stichting Reade, Amsterdam, Netherlands"
    ],
    "start_date": "2023-03-27",
    "completion_date": "2024-12-01",
    "last_update": "2024-12-13",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05704322"
  },
  {
    "nct_id": "NCT05734885",
    "title": "The Effect of Partner Massage in Labor on Pain, Anxiety and Birth Process",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 135,
    "conditions": [
      "Midwifery",
      "Labor Delivery",
      "Massage"
    ],
    "interventions": [
      {
        "name": "Back and Sacral massage massage application",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Ayşe Nur Ataş, Konya, Turkey (Türkiye)"
    ],
    "start_date": "2022-08-01",
    "completion_date": "2023-08-01",
    "last_update": "2024-12-02",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05734885"
  },
  {
    "nct_id": "NCT06717633",
    "title": "Comparison of Short-term Effects of Extracorporeal Shock Wave Therapy, Low-level Laser Therapy and Pulsed Electromagnetic Field Therapy in Knee Osteoarthritis",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE3"
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      {
        "name": "extracorporeal shock wave therapy",
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      {
        "name": "low-level laser therapy",
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      {
        "name": "pulsed electromagnetic field therapy",
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      "Istanbul Medeniyet University Goztepe Prof Dr Suleyman Yalcin City Hospital, Istanbul, None Selected, Turkey (Türkiye)"
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    "start_date": "2024-01-01",
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    "last_update": "2024-11-30",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06717633"
  },
  {
    "nct_id": "NCT04831606",
    "title": "Blue Light Photobiomodulation Therapy on Neuroischemic Patients",
    "status": "TERMINATED",
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      "NA"
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        "name": "debridement",
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      {
        "name": "Offloading",
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      {
        "name": "Advanced dressing",
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      {
        "name": "Blue Light Photobiomodulation",
        "type": "DEVICE"
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    ],
    "locations": [
      "San Donato Hospital, Arezzo, Italy"
    ],
    "start_date": "2021-07-31",
    "completion_date": "2024-07-01",
    "last_update": "2024-11-25",
    "topics": [
      "photobiomodulation"
    ],
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      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04831606"
  },
  {
    "nct_id": "NCT06280794",
    "title": "Efficacy of Laser Acupuncture for Idiopathic Bell's Palsy",
    "status": "UNKNOWN",
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      "NA"
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      "Bell's Palsy"
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        "name": "Laser acupuncture",
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      {
        "name": "Steroids",
        "type": "DRUG"
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    ],
    "locations": [
      "Beijing TongRen Hospital, Capital Medical University, Beijing, China"
    ],
    "start_date": "2021-03-01",
    "completion_date": "2026-02-01",
    "last_update": "2024-11-22",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06280794"
  },
  {
    "nct_id": "NCT06148753",
    "title": "An Investigation of the Effects of a Royal Jelly and Bee Venom-Derived Skin Serum on Skin Health and Signs of Aging",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
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      "NA"
    ],
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      "Skin Health"
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      {
        "name": "Manuka Health Eternal Renewal Regenerating Face Serum with Royal Jelly and Bee Venom",
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      }
    ],
    "locations": [
      "Citruslabs, Santa Monica, California, United States"
    ],
    "start_date": "2023-11-09",
    "completion_date": "2024-04-28",
    "last_update": "2024-11-18",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06148753"
  },
  {
    "nct_id": "NCT06113614",
    "title": "Effects of Photobiomodulation on Functional Recovery of Proximal Humerus Fractures",
    "status": "UNKNOWN",
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      "NA"
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        "name": "Physiotherapy",
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      },
      {
        "name": "Photobiomodulation",
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      {
        "name": "Simulation of photobiomodulation",
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      }
    ],
    "locations": [
      "ACN Municipal Hospital, São Paulo, Brazil"
    ],
    "start_date": "2024-04-30",
    "completion_date": "2026-04-30",
    "last_update": "2024-11-16",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06113614"
  },
  {
    "nct_id": "NCT06280846",
    "title": "High-intensity Versus Low-intensity Laser Acupuncture in Chronic, Non-specific Low Back Pain",
    "status": "COMPLETED",
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      "NA"
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        "name": "high-intensity laser acupuncture and Exercise therapy program",
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      {
        "name": "low-intensity laser acupuncture and Exercise therapy program",
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      {
        "name": "Sham laser acupuncture",
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      }
    ],
    "locations": [
      "Doaa Ayoub Elimy, Giza, Egypt"
    ],
    "start_date": "2024-03-15",
    "completion_date": "2024-10-30",
    "last_update": "2024-11-10",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06280846"
  },
  {
    "nct_id": "NCT05997069",
    "title": "Effects of Posterior-anterior Vertebral Mobilization Followed by Prone Press-up Exercise in Nonspecific Low Back Pain",
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      "NA"
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    "enrollment": 120,
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      "Low Back Pain",
      "Chronic Low-back Pain"
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      {
        "name": "Posterior-anterior vertebral mobilizations followed by Prone press-up exercise",
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        "name": "Conventional physiotherapy",
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    ],
    "locations": [
      "Sindh Institute Physical Medicine and Rehabilitation, Karachi, Sindh, Pakistan"
    ],
    "start_date": "2023-08-21",
    "completion_date": "2024-11-08",
    "last_update": "2024-11-10",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
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    "url": "https://clinicaltrials.gov/study/NCT05997069"
  },
  {
    "nct_id": "NCT06628609",
    "title": "Post-exercise Therapeutic Modalities on Functional Performance, Muscle Damage and Oxidative Stress of CrossFit® Athletes",
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      {
        "name": "PBMT-sMF",
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      {
        "name": "Shock wave",
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      {
        "name": "Pneumatic compression",
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    ],
    "locations": [
      "Laboratory of Phototherapy and Innovative Technologies in Health, São Paulo, São Paulo, Brazil"
    ],
    "start_date": "2024-10-11",
    "completion_date": "2024-11-03",
    "last_update": "2024-11-05",
    "topics": [
      "exercise-recovery",
      "photobiomodulation"
    ],
    "topic_names": [
      "Exercise Recovery",
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06628609"
  },
  {
    "nct_id": "NCT04541901",
    "title": "Massage and Cold Water Immersion on Movement Variability After Fatigue in Swimmers",
    "status": "COMPLETED",
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      "NA"
    ],
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      "Muscle Tone",
      "Perceived Exertion"
    ],
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      {
        "name": "Massage",
        "type": "OTHER"
      },
      {
        "name": "Cold water immersion",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Faculty of Science and Technology (UNESP), Presidente Prudente, São Paulo, Brazil"
    ],
    "start_date": "2023-03-06",
    "completion_date": "2023-09-30",
    "last_update": "2024-11-04",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04541901"
  },
  {
    "nct_id": "NCT05561582",
    "title": "The Effects of Intensity on Exercise-Induced Hypoalgesia During a Knee Extension Exercise",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Healthy"
    ],
    "interventions": [
      {
        "name": "Seated knee extension exercise",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Central Florida, Orlando, Florida, United States"
    ],
    "start_date": "2022-10-31",
    "completion_date": "2023-03-27",
    "last_update": "2024-10-30",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05561582"
  },
  {
    "nct_id": "NCT06640595",
    "title": "Simulation Study on Advanced Medical Procedures Under Extreme Environments",
    "status": "COMPLETED",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 36,
    "conditions": [
      "Cold Exposure"
    ],
    "interventions": [],
    "locations": [
      "Eurac Research, Bolzano, Italy"
    ],
    "start_date": "2023-10-16",
    "completion_date": "2023-10-17",
    "last_update": "2024-10-12",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06640595"
  },
  {
    "nct_id": "NCT05924919",
    "title": "The Effects of Passive Heat Therapy in Patients With Chronic Kidney Disease",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 10,
    "conditions": [
      "Renal Insufficiency, Chronic"
    ],
    "interventions": [
      {
        "name": "Whole-body Passive Heat Therapy (HT)",
        "type": "PROCEDURE"
      },
      {
        "name": "Thermoneutral Control (CON)",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Virginia Commonwealth University, Richmond, Virginia, United States"
    ],
    "start_date": "2023-09-18",
    "completion_date": "2024-03-19",
    "last_update": "2024-10-07",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05924919"
  },
  {
    "nct_id": "NCT05985967",
    "title": "Therapeutic Modalities on Exercise Performance and Post-exercise Recovery of CrossFit® Athletes",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 12,
    "conditions": [
      "Muscle Strength"
    ],
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      {
        "name": "PBMT-sMF",
        "type": "DEVICE"
      },
      {
        "name": "Shock wave",
        "type": "DEVICE"
      },
      {
        "name": "Pneumatic compression",
        "type": "DEVICE"
      },
      {
        "name": "Passive recovery",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Laboratory of Phototherapy and Innovative Technologies in Health, São Paulo, Brazil"
    ],
    "start_date": "2023-08-09",
    "completion_date": "2023-09-10",
    "last_update": "2024-09-03",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05985967"
  },
  {
    "nct_id": "NCT05860049",
    "title": "Adding Instrument Assisted Soft Tissue Mobilization to Core Stability Training in Chronic Mechanical Neck Pain",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 52,
    "conditions": [
      "Neck Pain"
    ],
    "interventions": [
      {
        "name": "Conventional physiotherapy",
        "type": "OTHER"
      },
      {
        "name": "Core stability",
        "type": "OTHER"
      },
      {
        "name": "Instrument assisted soft tissue mobilization",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Ismailia Medical Complex, Ismailia, Egypt"
    ],
    "start_date": "2023-08-29",
    "completion_date": "2024-03-30",
    "last_update": "2024-08-20",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05860049"
  },
  {
    "nct_id": "NCT02898233",
    "title": "Augmenting Internet-Based Cognitive Behavioral Therapy for Major Depressive Disorder With Low-Level Light Therapy",
    "status": "TERMINATED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 20,
    "conditions": [
      "Depression"
    ],
    "interventions": [
      {
        "name": "Deprexis",
        "type": "OTHER"
      },
      {
        "name": "Active low-level light therapy",
        "type": "DEVICE"
      },
      {
        "name": "Sham low-level light therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "The University of Texas at Austin, Austin, Texas, United States"
    ],
    "start_date": "2016-02",
    "completion_date": "2020-11-30",
    "last_update": "2024-07-23",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02898233"
  },
  {
    "nct_id": "NCT06520761",
    "title": "The Effect of Injectable PRF Vs LLL on Orthodontic Tooth Movement",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 20,
    "conditions": [
      "Rate of Canine Retraction",
      "Root Resorption"
    ],
    "interventions": [
      {
        "name": "Injectable platelet rich fibrin",
        "type": "PROCEDURE"
      },
      {
        "name": "Low Level LASER",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Faculty of Dental Medicine for Girls Al Azhar university, Cairo, Naser City, Egypt"
    ],
    "start_date": "2022-11-01",
    "completion_date": "2024-12-01",
    "last_update": "2024-07-20",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06520761"
  },
  {
    "nct_id": "NCT06507761",
    "title": "Thermotherapy in Acute Nonspecific Neck Pain",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Neck Pain",
      "Cold"
    ],
    "interventions": [
      {
        "name": "Sham",
        "type": "OTHER"
      },
      {
        "name": "Hot Pack",
        "type": "OTHER"
      },
      {
        "name": "Cold Pack",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Nuray ALACA, Istanbul, Turkey (Türkiye)",
      "Acibadem University, Istanbul, Turkey (Türkiye)"
    ],
    "start_date": "2024-07-10",
    "completion_date": "2025-07-10",
    "last_update": "2024-07-12",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06507761"
  },
  {
    "nct_id": "NCT06433856",
    "title": "Neuromuscular Responses to Recovery Techniques",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 16,
    "conditions": [
      "Muscle Soreness"
    ],
    "interventions": [
      {
        "name": "Cold Water Immersion",
        "type": "OTHER"
      },
      {
        "name": "Percussive Massage Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "CdL in Fisioterapia, Trieste, Italy"
    ],
    "start_date": "2023-05-01",
    "completion_date": "2023-07-31",
    "last_update": "2024-06-16",
    "topics": [
      "cold-water-immersion",
      "exercise-recovery"
    ],
    "topic_names": [
      "Cold-Water Immersion",
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06433856"
  },
  {
    "nct_id": "NCT05360836",
    "title": "The Effect of Motor Imagery in Patients With Radius Distal End Fracture",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Distal Radius Fracture"
    ],
    "interventions": [
      {
        "name": "Conservative treatment via telerehabilitation",
        "type": "OTHER"
      },
      {
        "name": "Conservative treatmen + motor imagery",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Melike Gizem Kalaycı, Istanbul, Turkey (Türkiye)"
    ],
    "start_date": "2021-10-01",
    "completion_date": "2022-05-30",
    "last_update": "2024-06-09",
    "topics": [
      "contrast-therapy"
    ],
    "topic_names": [
      "Contrast Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05360836"
  },
  {
    "nct_id": "NCT04060745",
    "title": "Glucose Metabolism in Brown Adipose Tissue (BAT) in Young Healthy Men Evaluated by Deuterium Metabolic Imaging (DMI)",
    "status": "TERMINATED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 10,
    "conditions": [
      "Type2 Diabetes",
      "Obesity",
      "Metabolic Syndrome"
    ],
    "interventions": [
      {
        "name": "cooling using a water-perfused vest",
        "type": "OTHER"
      },
      {
        "name": "thermoneutrality",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark"
    ],
    "start_date": "2019-08-01",
    "completion_date": "2022-12-01",
    "last_update": "2024-06-06",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04060745"
  },
  {
    "nct_id": "NCT06424158",
    "title": "Massage Therapy After Thoracic or Lumbar Surgery",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 100,
    "conditions": [
      "Scoliosis; Adolescence",
      "Adolescent Idiopathic Scoliosis, Thoracic Region",
      "Adolescent Idiopathic Scoliosis, Lumbar Region"
    ],
    "interventions": [
      {
        "name": "Massage Therapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Cook Children's Medical Center, Fort Worth, Texas, United States"
    ],
    "start_date": "2021-02-17",
    "completion_date": "2026-08-01",
    "last_update": "2024-05-22",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06424158"
  },
  {
    "nct_id": "NCT06432348",
    "title": "Pilates Exercises and Soccer: A Comparative Study of Mat vs. Reformer on FMS and ROM",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Sports, Mechanical"
    ],
    "interventions": [
      {
        "name": "Reformer pilates",
        "type": "OTHER"
      },
      {
        "name": "Mat Pilates",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Osmaniye Korkut Ata University, Osmaniye, Turkey (Türkiye)"
    ],
    "start_date": "2021-11-11",
    "completion_date": "2022-04-30",
    "last_update": "2024-05-21",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06432348"
  },
  {
    "nct_id": "NCT03593733",
    "title": "Comparison Between Photobiomodulation Therapy (PBMT) and a Cold-Water Immersion (CWI) in Recovery Soccer Player: Analysis of Biochemical Markers of Recovery and Muscular Oxidative Stress.",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 18,
    "conditions": [
      "Soccer",
      "Fatigue",
      "Oxidative Stress",
      "Recovery",
      "Cold Water Immersion",
      "Photobiomodulation Therapy"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation Therapy",
        "type": "OTHER"
      },
      {
        "name": "Cold Water Immersion",
        "type": "OTHER"
      }
    ],
    "locations": [],
    "start_date": "2017-01",
    "completion_date": "2019-05",
    "last_update": "2024-05-06",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03593733"
  },
  {
    "nct_id": "NCT06405282",
    "title": "Weightlessness Associated Cephalad Fluid Shifts; The Potential to Evaluate Venous and Lymphatic Dysfunction",
    "status": "COMPLETED",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 15,
    "conditions": [
      "Fluid Retention Tissue",
      "Perfusion; Complications"
    ],
    "interventions": [
      {
        "name": "Manual Lymphatic Drainage",
        "type": "OTHER"
      },
      {
        "name": "Near infrared spectroscopy",
        "type": "DEVICE"
      },
      {
        "name": "Temperature",
        "type": "DEVICE"
      },
      {
        "name": "Tissue Dialectic Constant",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Nova Southeastern University, Fort Lauderdale, Florida, United States"
    ],
    "start_date": "2022-04-14",
    "completion_date": "2022-06-25",
    "last_update": "2024-05-03",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06405282"
  },
  {
    "nct_id": "NCT06319183",
    "title": "The Regulatory Function of Inhaled Asthma Medication Salbutamol on Thermogenesis",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "EARLY_PHASE1"
    ],
    "enrollment": 30,
    "conditions": [
      "Effect of Asthma Medication Salbutamol on Obesity"
    ],
    "interventions": [
      {
        "name": "Salbutamol",
        "type": "DRUG"
      }
    ],
    "locations": [],
    "start_date": "2024-03",
    "completion_date": "2025-03",
    "last_update": "2024-03-13",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06319183"
  },
  {
    "nct_id": "NCT05760092",
    "title": "The Use of Photobiomodulation in the Treatment of Oral Complaints of Long COVID-19.A Randomized Controlled Trial.",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE2"
    ],
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    "conditions": [
      "Xerostomia",
      "COVID-19",
      "Long COVID",
      "Persistent COVID-19"
    ],
    "interventions": [
      {
        "name": "Institutional standard treatment for xerostomia and Long Covid",
        "type": "COMBINATION_PRODUCT"
      },
      {
        "name": "Photobiomodulation Therapy",
        "type": "RADIATION"
      },
      {
        "name": "Placebo Photobiomodulation Therapy",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "Universidade Nove de Julho / Post-Graduate program Biophotonics Applied to Health Sciences, São Paulo, Brazil"
    ],
    "start_date": "2023-03-01",
    "completion_date": "2024-03-08",
    "last_update": "2024-03-09",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05760092"
  },
  {
    "nct_id": "NCT04891692",
    "title": "Effect of Neuromuscular Electrical Stimulation in Patients With Chronic Low Back Pain",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Low Back Pain",
      "Paraspinal Muscles"
    ],
    "interventions": [
      {
        "name": "StimaWell 120MTRS system",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "PEFORM Centre, Montreal, Quebec, Canada"
    ],
    "start_date": "2021-02-22",
    "completion_date": "2024-02-23",
    "last_update": "2024-03-07",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04891692"
  },
  {
    "nct_id": "NCT04415970",
    "title": "Understanding Physiology During Float-REST and the Consequential Effects on Subjective and Objective Recovery",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 31,
    "conditions": [
      "Sleep Quality"
    ],
    "interventions": [
      {
        "name": "Flotation therapy sensory deprivation tank",
        "type": "OTHER"
      },
      {
        "name": "Sleep Pod",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Rockefeller Neuroscience Institute at West Virginia University, Morgantown, West Virginia, United States"
    ],
    "start_date": "2020-01-10",
    "completion_date": "2023-02-15",
    "last_update": "2024-03-05",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04415970"
  },
  {
    "nct_id": "NCT04011072",
    "title": "Far Infrared Therapy on Arteriovenous Fistulas in Hemodialysis Patients",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 206,
    "conditions": [
      "Arterio-venous Fistula"
    ],
    "interventions": [
      {
        "name": "Far infrared radiation",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "Rigshospitalet, Copenhagen, Denmark",
      "Frederiksberg Hospital, Frederiksberg, Denmark",
      "Herlev Hospital, Herlev, Denmark",
      "Hilleroed Hospital, Hillerød, Denmark",
      "Holbæk Hospital, Holbæk, Denmark",
      "Hvidovre Hospital, Hvidovre, Denmark",
      "Nykøbing Falster Hospital, Nykøbing Falster, Denmark",
      "Roskilde Hospital, Roskilde, Denmark"
    ],
    "start_date": "2019-10-03",
    "completion_date": "2023-08-29",
    "last_update": "2024-02-28",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04011072"
  },
  {
    "nct_id": "NCT04732247",
    "title": "Oxytocin for Oxidative Stress and Inflammation",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE2"
    ],
    "enrollment": 40,
    "conditions": [
      "Oxidative Stress",
      "Inflammation"
    ],
    "interventions": [
      {
        "name": "Oxytocin nasal spray",
        "type": "DRUG"
      },
      {
        "name": "Placebo nasal spray",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Translational Genomics Research Institute, Phoenix, Arizona, United States",
      "University of Florida, Gainesville, Florida, United States",
      "Florida Institute for Human and Machine Cognition, Pensacola, Florida, United States"
    ],
    "start_date": "2022-02-01",
    "completion_date": "2023-09-15",
    "last_update": "2024-02-21",
    "topics": [
      "cold-water-immersion",
      "exercise-recovery"
    ],
    "topic_names": [
      "Cold-Water Immersion",
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04732247"
  },
  {
    "nct_id": "NCT05478200",
    "title": "Development of a Tele-Physiotherapy Tool for the Early Management of Muskuloskeletal Pain in People With Visual Impairement (TeleEDxPhysio)",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 128,
    "conditions": [
      "Low Back Pain",
      "Visual Impairment"
    ],
    "interventions": [
      {
        "name": "physical exercise",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Manual therapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Universidad de Zaragoza (Clínica Valdespartera y CS Seminario), Zaragoza, Aragon, Spain",
      "Escuela Unviersitaria de Fisioterapia de la ONCE, Madrid, Spain"
    ],
    "start_date": "2022-11-14",
    "completion_date": "2024-12-15",
    "last_update": "2024-02-19",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05478200"
  },
  {
    "nct_id": "NCT06265142",
    "title": "Clean Catch Urine Feasibility and Contamination Rate Compared to Bladder Catheterization Urine in Pre-Continent Children",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 80,
    "conditions": [
      "Urinary Tract Infections"
    ],
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      {
        "name": "Bladder catheterization",
        "type": "PROCEDURE"
      },
      {
        "name": "clean catch urine via bladder massage technique",
        "type": "PROCEDURE"
      }
    ],
    "locations": [],
    "start_date": "2024-02-15",
    "completion_date": "2024-12-01",
    "last_update": "2024-02-14",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06265142"
  },
  {
    "nct_id": "NCT06248541",
    "title": "The Effect of Low-Level Laser Therapy in Carpal Tunnel Syndrome",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Carpal Tunnel Syndrome"
    ],
    "interventions": [
      {
        "name": "treatment with low-level laser therapy",
        "type": "DEVICE"
      },
      {
        "name": "treatment with conventional light diodes",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Medical University Graz, Graz, Styria, Austria"
    ],
    "start_date": "2023-08-03",
    "completion_date": "2025-12-31",
    "last_update": "2024-02-05",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06248541"
  },
  {
    "nct_id": "NCT06224114",
    "title": "Coloured-light in Retinitis Pigmentosa.",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 70,
    "conditions": [
      "Retinitis Pigmentosa"
    ],
    "interventions": [
      {
        "name": "Coloured-light torch",
        "type": "DEVICE"
      },
      {
        "name": "Different coloured-light torch",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom"
    ],
    "start_date": "2024-03",
    "completion_date": "2024-10",
    "last_update": "2024-01-24",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06224114"
  },
  {
    "nct_id": "NCT06215079",
    "title": "Investigation of the Efficacy of Transcranial Magnetic Stimulation in Patients Developing Complex Regional Pain Syndrome Type 1 in the Upper Extremity During the Subacute-Chronic Period After Ischemic Stroke",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 45,
    "conditions": [
      "Complex Regional Pain Syndromes"
    ],
    "interventions": [
      {
        "name": "The Magstim Rapid2 Plus Magnetic Stimulator (Magstim, Whitland, Dyfed, UK)",
        "type": "DEVICE"
      },
      {
        "name": "Sham transcranial magnetic stimulation",
        "type": "DEVICE"
      },
      {
        "name": "conventional rehabilitation program",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Ankara Bilkent City Hospital Physical Therapy and Rehabilitation Hospital, Ankara, Turkey (Türkiye)"
    ],
    "start_date": "2023-11-15",
    "completion_date": "2024-12-15",
    "last_update": "2024-01-18",
    "topics": [
      "contrast-therapy"
    ],
    "topic_names": [
      "Contrast Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06215079"
  },
  {
    "nct_id": "NCT05497791",
    "title": "Stroke, Measurement and Rehabilitation",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 18,
    "conditions": [
      "Stroke"
    ],
    "interventions": [
      {
        "name": "transcranial laser stimulation associated with NMES",
        "type": "DEVICE"
      },
      {
        "name": "Placebo",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Fernanda Rossi Paolillo, São Carlos, São Paulo, Brazil"
    ],
    "start_date": "2019-05-01",
    "completion_date": "2019-12-20",
    "last_update": "2024-01-18",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05497791"
  },
  {
    "nct_id": "NCT06217367",
    "title": "Over-the-Counter Antihistamines & Heat Stress",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE4"
    ],
    "enrollment": 16,
    "conditions": [
      "Heat Illness",
      "Allergic Rhinitis",
      "Heat Injury",
      "Sudomotor Sympathetic Dysfunction"
    ],
    "interventions": [
      {
        "name": "50 mg Diphenhydramine",
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      },
      {
        "name": "10 mg Loratadine",
        "type": "DRUG"
      },
      {
        "name": "5 mg Desloratadine",
        "type": "DRUG"
      },
      {
        "name": "Placebo (Sugar Pill)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Lakehead University C.J Sanders Fieldhouse, Thunder Bay, Ontario, Canada"
    ],
    "start_date": "2023-12-05",
    "completion_date": "2024-06",
    "last_update": "2024-01-11",
    "topics": [
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06217367"
  },
  {
    "nct_id": "NCT06217224",
    "title": "Evaluation of Prophylactic Photobiomodulation Therapy in Patients With Osteosarcoma",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 53,
    "conditions": [
      "Mucositis Oral"
    ],
    "interventions": [
      {
        "name": "Preventive photobiomodulation Therapy (PBMT)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "National Cancer Institute, Rio de Janeiro, Brazil"
    ],
    "start_date": "2022-10-17",
    "completion_date": "2025-07-30",
    "last_update": "2024-01-11",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06217224"
  },
  {
    "nct_id": "NCT06214104",
    "title": "Acupressure Therapy Method and Heel Blood Effect of Position on Pain and Physiological Parameters",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 90,
    "conditions": [
      "Newborn; Vitality"
    ],
    "interventions": [
      {
        "name": "Acupressur",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Eastern Mediterranean University, Famagusta, Cyprus"
    ],
    "start_date": "2024-02-01",
    "completion_date": "2024-08-01",
    "last_update": "2024-01-10",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06214104"
  },
  {
    "nct_id": "NCT06199115",
    "title": "Prevention of Neuropathic Pain From Oxaliplatin by Photobiomodulation",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 70,
    "conditions": [
      "Cancer of the Gastrointestinal Tract"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "CHP Saint-Grégoire, Saint-Grégoire, France"
    ],
    "start_date": "2023-05-31",
    "completion_date": "2025-04",
    "last_update": "2024-01-09",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06199115"
  },
  {
    "nct_id": "NCT05630417",
    "title": "Investigation of the Effect of Geriatric Massage",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Nursing Caries"
    ],
    "interventions": [
      {
        "name": "Feet and Back Massage",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Bayburt University, Bayburt, Turkey (Türkiye)"
    ],
    "start_date": "2022-03-15",
    "completion_date": "2023-10-30",
    "last_update": "2024-01-08",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05630417"
  },
  {
    "nct_id": "NCT06193291",
    "title": "Effect of Hot Water Immersion on Heart Rate Variability and Glucose",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 28,
    "conditions": [
      "Glucose Tolerance",
      "HRV"
    ],
    "interventions": [
      {
        "name": "Feet heating",
        "type": "PROCEDURE"
      },
      {
        "name": "Calf heating",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "San Diego State University, San Diego, California, United States"
    ],
    "start_date": "2020-03-02",
    "completion_date": "2021-03-01",
    "last_update": "2024-01-04",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06193291"
  },
  {
    "nct_id": "NCT05647473",
    "title": "Efficacy, Safety and Response Predictors of Adjuvant Astragalus for Cognition in Orthostatic Hypotension",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE2"
    ],
    "enrollment": 66,
    "conditions": [
      "Orthostatic Hypotension",
      "Alzheimer Disease"
    ],
    "interventions": [
      {
        "name": "Routine treatment",
        "type": "BEHAVIORAL"
      },
      {
        "name": "add-on low dose Astragalus",
        "type": "DRUG"
      },
      {
        "name": "add-on high dose Astragalus",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Fujian Medical University Union Hospital, Fuzhou, Fujian, China"
    ],
    "start_date": "2024-02-20",
    "completion_date": "2025-05-30",
    "last_update": "2024-01-02",
    "topics": [
      "sauna-heat-therapy",
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sauna & Heat Therapy",
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05647473"
  },
  {
    "nct_id": "NCT06159374",
    "title": "Effects of Physical Training in Altered Environmental Conditions on Exercise Performance",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 128,
    "conditions": [
      "Hypoxia, Altitude",
      "Cold Exposure",
      "Heat Exposure"
    ],
    "interventions": [
      {
        "name": "exercise and environmental conditions",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University School of Physical Education in Cracow, Krakow, Poland"
    ],
    "start_date": "2022-01-01",
    "completion_date": "2025-12-31",
    "last_update": "2023-12-06",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06159374"
  },
  {
    "nct_id": "NCT05194488",
    "title": "Evolving Treatment Modalities for Management of Patients Suffering From Disc Displacement With Reduction",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 27,
    "conditions": [
      "Temporomandibular Joint Disc Displacement, With Reduction"
    ],
    "interventions": [
      {
        "name": "Low level laser therapy",
        "type": "DEVICE"
      },
      {
        "name": "Botulinum toxin type A",
        "type": "DRUG"
      },
      {
        "name": "Anterior repositioning appliance",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Faculty of Dentistry, Alexandria University, Alexandria, Egypt"
    ],
    "start_date": "2022-01-10",
    "completion_date": "2022-06-01",
    "last_update": "2023-12-01",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05194488"
  },
  {
    "nct_id": "NCT05553184",
    "title": "Activation of Brown Adipose Tissue Thermogenesis in Humans Using Formoterol Fumarate (GB10)",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 12,
    "conditions": [
      "Type 2 Diabetes",
      "Obesity"
    ],
    "interventions": [
      {
        "name": "Formoterol Fumarate 12 micrograms Inhalation Powder",
        "type": "DRUG"
      },
      {
        "name": "Nicotinic Acid 50 MG Oral Tablet",
        "type": "DRUG"
      },
      {
        "name": "Acute Cold Exposure",
        "type": "OTHER"
      },
      {
        "name": "Positron Emission Tomography (PET)",
        "type": "DIAGNOSTIC_TEST"
      },
      {
        "name": "Indirect calorimetry",
        "type": "DIAGNOSTIC_TEST"
      },
      {
        "name": "dual-energy x-ray absorptiometry (DEXA scan)",
        "type": "DIAGNOSTIC_TEST"
      },
      {
        "name": "Biopsy",
        "type": "PROCEDURE"
      },
      {
        "name": "iv lines",
        "type": "PROCEDURE"
      },
      {
        "name": "Electromyogram (EMG)",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Centre de recherche du CHUS, Sherbrooke, Quebec, Canada"
    ],
    "start_date": "2022-07-05",
    "completion_date": "2023-05-29",
    "last_update": "2023-11-27",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05553184"
  },
  {
    "nct_id": "NCT05585346",
    "title": "Photobiomodulation Therapy for Idiopathic Facial Paralysis",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 96,
    "conditions": [
      "Bell's Palsy"
    ],
    "interventions": [
      {
        "name": "MLS laser",
        "type": "DEVICE"
      },
      {
        "name": "Oral vitamin B1",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Beijing TongRen Hospital, Capital Medical University, Beijing, China"
    ],
    "start_date": "2021-01-01",
    "completion_date": "2023-02-20",
    "last_update": "2023-11-21",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05585346"
  },
  {
    "nct_id": "NCT05822960",
    "title": "To Investigate the Effect of Far-infrared Radiation on Lower Extremity Acupoints on the Blood Circulation of Lower Extremities in Patients With Hemodialysis",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 32,
    "conditions": [
      "Peripheral Arterial Disease"
    ],
    "interventions": [
      {
        "name": "far-infrared radiation",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "National Taiwan University Hospital Yunlin Branch hemodialysis room, Huwei, Taiwan",
      "National Taiwan University Hospital Yunlin Branch hemodialysis room, Huwei, Taiwan"
    ],
    "start_date": "2023-02-20",
    "completion_date": "2023-08-10",
    "last_update": "2023-11-19",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05822960"
  },
  {
    "nct_id": "NCT06147557",
    "title": "Effect of Passive Heat Therapy on Metabolism",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 25,
    "conditions": [
      "Healthy"
    ],
    "interventions": [
      {
        "name": "Heat therapy",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Institute of Sport Science and Innovations, Kaunas, Lithuania"
    ],
    "start_date": "2020-10-01",
    "completion_date": "2022-05-31",
    "last_update": "2023-11-17",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06147557"
  },
  {
    "nct_id": "NCT06139276",
    "title": "Outcomes of Frozen Shoulder Treated With Small Needle-Knife Through Microcirculation and Pulse Analysis.",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 120,
    "conditions": [
      "Frozen Shoulder"
    ],
    "interventions": [
      {
        "name": "Small Needle-Knife",
        "type": "PROCEDURE"
      },
      {
        "name": "Standard treatment",
        "type": "OTHER"
      }
    ],
    "locations": [],
    "start_date": "2024-01-01",
    "completion_date": "2025-12-31",
    "last_update": "2023-11-17",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06139276"
  },
  {
    "nct_id": "NCT06125639",
    "title": "Effects of Sauna Bathing on Sleep, Mood and Stress",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Healthy"
    ],
    "interventions": [
      {
        "name": "Sauna Bathing",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "University School of Physical Education in Cracow, Krakow, Poland",
      "University School of Physical Education in Cracow, Krakow, Poland"
    ],
    "start_date": "2023-10-20",
    "completion_date": "2024-05",
    "last_update": "2023-11-04",
    "topics": [
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06125639"
  },
  {
    "nct_id": "NCT05456568",
    "title": "LymphAssistTM at Home (LAAH)",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Lymphedema Arm",
      "Lymphedema of Leg"
    ],
    "interventions": [
      {
        "name": "LymphAssistTM Professional",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Swansea Bay University Health Board, Swansea, United Kingdom"
    ],
    "start_date": "2022-07-06",
    "completion_date": "2023-09-25",
    "last_update": "2023-10-26",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05456568"
  },
  {
    "nct_id": "NCT05799209",
    "title": "Floatation-REST in Methamphetamine Use Disorder: A Pilot Study",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 100,
    "conditions": [
      "Amphetamine-Type Substance Use Disorder"
    ],
    "interventions": [
      {
        "name": "Float Pool",
        "type": "DEVICE"
      },
      {
        "name": "Float Chair",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Laureate Institute for Brain Research, Tulsa, Oklahoma, United States"
    ],
    "start_date": "2022-03-15",
    "completion_date": "2024-08-01",
    "last_update": "2023-10-04",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05799209"
  },
  {
    "nct_id": "NCT03899090",
    "title": "Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and Depression",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 75,
    "conditions": [
      "Generalized Anxiety Disorder",
      "Social Anxiety Disorder",
      "Panic Disorder",
      "Agoraphobia",
      "Posttraumatic Stress Disorder",
      "Major Depressive Disorder"
    ],
    "interventions": [
      {
        "name": "Float pool",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Float chair",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Laureate Institute for Brain Research, Tulsa, Oklahoma, United States"
    ],
    "start_date": "2019-04-08",
    "completion_date": "2024-05-31",
    "last_update": "2023-10-04",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03899090"
  },
  {
    "nct_id": "NCT03610451",
    "title": "Floatation-REST and Anorexia Nervosa",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 68,
    "conditions": [
      "Anorexia Nervosa"
    ],
    "interventions": [
      {
        "name": "Floatation-REST plus usual care",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Usual care",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Laureate Institute for Brain Research, Tulsa, Oklahoma, United States"
    ],
    "start_date": "2018-03-16",
    "completion_date": "2024-10",
    "last_update": "2023-10-04",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03610451"
  },
  {
    "nct_id": "NCT05294965",
    "title": "Beta 2 Adrenergic Stimulation vs Cold Exposure to Activate Human Brown Adipose Tissue",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "EARLY_PHASE1"
    ],
    "enrollment": 12,
    "conditions": [
      "Thermogenesis"
    ],
    "interventions": [
      {
        "name": "Fenoterol",
        "type": "DRUG"
      },
      {
        "name": "Mild cold exposure",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University Hospital Basel, Dept. of Endocrinology, Basel, Switzerland"
    ],
    "start_date": "2022-04-27",
    "completion_date": "2023-03-06",
    "last_update": "2023-09-25",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05294965"
  },
  {
    "nct_id": "NCT05930587",
    "title": "Effect of Cold Immersion on Patients With Varicose Vein",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Varicose Veins of Lower Limb"
    ],
    "interventions": [
      {
        "name": "Cold water immersion",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Nevra Kalkan, Ankara, Gazi University Faculty of Nursing, Turkey (Türkiye)"
    ],
    "start_date": "2023-09-25",
    "completion_date": "2024-03-30",
    "last_update": "2023-09-22",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05930587"
  },
  {
    "nct_id": "NCT04890002",
    "title": "Improving Sleep With the Far-infrared Emitting Pyjamas",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Sleep Disorder"
    ],
    "interventions": [
      {
        "name": "Far-infrared emitting pyjamas",
        "type": "DEVICE"
      },
      {
        "name": "Sham-pyjamas",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Wing Fai YEUNG, Hong Kong, Hong Kong"
    ],
    "start_date": "2021-07-15",
    "completion_date": "2022-03-31",
    "last_update": "2023-09-21",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04890002"
  },
  {
    "nct_id": "NCT05475327",
    "title": "Relaxation Exercises for Low Back Pain and Insomnia in the Third Trimester of Pregnancy",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Low Back Pain"
    ],
    "interventions": [
      {
        "name": "Conventional Physical Therapy",
        "type": "OTHER"
      },
      {
        "name": "Relaxation exercises",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Bashir Hospital, Sialkot, Punjab Province, Pakistan"
    ],
    "start_date": "2021-12-01",
    "completion_date": "2022-08-01",
    "last_update": "2023-09-15",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05475327"
  },
  {
    "nct_id": "NCT06036654",
    "title": "Infrared Bioeffect System for the Treatment of Onychomycosis",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Hyperthermia"
    ],
    "interventions": [
      {
        "name": "infrared thermotherapy instrument",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China"
    ],
    "start_date": "2023-02-24",
    "completion_date": "2024-08-24",
    "last_update": "2023-09-12",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT06036654"
  },
  {
    "nct_id": "NCT04833699",
    "title": "The Effect of Hot Pack Application on Postoperative Ileus Undergoing Surgery for Gynecologic Malignancies",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 130,
    "conditions": [
      "Postoperative Ileus"
    ],
    "interventions": [
      {
        "name": "rubber water bag",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Mugla Sıtkı Kocman University Education and Research Hospital, Muğla, Turkey (Türkiye)"
    ],
    "start_date": "2021-04-05",
    "completion_date": "2023-04-30",
    "last_update": "2023-09-04",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04833699"
  },
  {
    "nct_id": "NCT05973162",
    "title": "Effects of Virtual Reality in Pediatric Burn Patients",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Burns Elbows",
      "Pediatric ALL"
    ],
    "interventions": [
      {
        "name": "Virtual Realty Training",
        "type": "OTHER"
      },
      {
        "name": "Transverse friction massage (TFM)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Burn units of Rawalpindi/Islamabad (PIMS hospital, Max Health hospital), Islamabad, Punjab Province, Pakistan"
    ],
    "start_date": "2023-08-30",
    "completion_date": "2024-04-28",
    "last_update": "2023-08-31",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05973162"
  },
  {
    "nct_id": "NCT05859321",
    "title": "Virtual Reality Based Physical Therapy for Patients With Lower Back Pain",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 84,
    "conditions": [
      "Chronic Low-back Pain"
    ],
    "interventions": [
      {
        "name": "Virtual reality Exercises",
        "type": "OTHER"
      },
      {
        "name": "Routine Physiotherapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Lahore, Lahore, Punjab Province, Pakistan"
    ],
    "start_date": "2023-05-15",
    "completion_date": "2023-08-05",
    "last_update": "2023-08-06",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05859321"
  },
  {
    "nct_id": "NCT05260918",
    "title": "Examining the Effects of Float-REST for Recovery in Individuals With Chronic Lower Back Pain",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 24,
    "conditions": [
      "Pain, Chronic"
    ],
    "interventions": [
      {
        "name": "Float-REST",
        "type": "OTHER"
      },
      {
        "name": "Nappod",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Rockefeller Neuroscience Institute at West Virginia University, Morgantown, West Virginia, United States"
    ],
    "start_date": "2022-02-24",
    "completion_date": "2023-01-01",
    "last_update": "2023-07-19",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05260918"
  },
  {
    "nct_id": "NCT05897931",
    "title": "Effects of Two Different Applications in Fibromyalgia",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 34,
    "conditions": [
      "Fibromyalgia"
    ],
    "interventions": [
      {
        "name": "Connective tissue massage",
        "type": "OTHER"
      },
      {
        "name": "Kinesio Tape Application",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Yeditepe University, Istanbul, Turkey (Türkiye)"
    ],
    "start_date": "2023-06-01",
    "completion_date": "2023-07-07",
    "last_update": "2023-07-09",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05897931"
  },
  {
    "nct_id": "NCT05040477",
    "title": "Muscle Energy Technique and Facet Joint Mobilization in Chronic Neck Pain.",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 105,
    "conditions": [
      "Chronic Neck Pain"
    ],
    "interventions": [
      {
        "name": "Muscle energy Technique",
        "type": "OTHER"
      }
    ],
    "locations": [
      "HIT Taxila Cantt Hospital, Rawalpindi, Punjab Province, Pakistan"
    ],
    "start_date": "2020-08-30",
    "completion_date": "2021-07-31",
    "last_update": "2023-07-07",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05040477"
  },
  {
    "nct_id": "NCT05451888",
    "title": "Assessing Effects of Mineral-rich Floatation Spa Treatment on Mood and Psychological Health Outcomes",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 55,
    "conditions": [
      "Mood"
    ],
    "interventions": [
      {
        "name": "Spa treatment",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "School of Psychology, Reading, Berkshire, United Kingdom"
    ],
    "start_date": "2022-06-01",
    "completion_date": "2022-12-31",
    "last_update": "2023-05-25",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05451888"
  },
  {
    "nct_id": "NCT05266209",
    "title": "Comparison of Coconut and Sunflower Oil Application in Preserving Babies' Skin Integrity",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 66,
    "conditions": [
      "Skin Care"
    ],
    "interventions": [
      {
        "name": "Coconut oil skin care group",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Sakarya Education and Training Hospital, Sakarya, Adapazarı, Turkey (Türkiye)"
    ],
    "start_date": "2022-03-25",
    "completion_date": "2023-05-12",
    "last_update": "2023-05-13",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05266209"
  },
  {
    "nct_id": "NCT05265806",
    "title": "The Effects of Oxytocin Treatment on Social Touch",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 180,
    "conditions": [
      "Healthy"
    ],
    "interventions": [
      {
        "name": "Intranasal oxytocin",
        "type": "DRUG"
      },
      {
        "name": "Oral oxytocin",
        "type": "DRUG"
      },
      {
        "name": "Placebo",
        "type": "DRUG"
      }
    ],
    "locations": [
      "University of Electronic Science and Technology of China(UESTC), Chengdu, Sichuan, China"
    ],
    "start_date": "2021-09-01",
    "completion_date": "2022-05-25",
    "last_update": "2023-05-10",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05265806"
  },
  {
    "nct_id": "NCT05612646",
    "title": "The Effect of Acupressure in Improving Constipation Among Inpatients in Neurology Departments",
    "status": "COMPLETED",
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      "NA"
    ],
    "enrollment": 128,
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      "Constipation"
    ],
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      {
        "name": "Acupressure",
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      },
      {
        "name": "routine nursing and fake acupressure",
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      }
    ],
    "locations": [
      "1650 Taiwan Boulevard Sect. 4, Taichung, Taiwan"
    ],
    "start_date": "2020-09-11",
    "completion_date": "2022-10-24",
    "last_update": "2023-05-07",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05612646"
  },
  {
    "nct_id": "NCT05610046",
    "title": "The Impact of Passive Heat Treatment on Glycaemic Response During an Oral Glucose Tolerance Test in Diabetic Patients",
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      "NA"
    ],
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      "Diabetes Mellitus, Type 2"
    ],
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        "name": "Infrared sauna heating",
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      {
        "name": "Sham sauna",
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      }
    ],
    "locations": [
      "Maastricht University Medical Centre +, Maastricht, Netherlands"
    ],
    "start_date": "2023-01-26",
    "completion_date": "2023-12-31",
    "last_update": "2023-05-03",
    "topics": [
      "infrared-sauna",
      "sauna-heat-therapy"
    ],
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      "Infrared Sauna",
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05610046"
  },
  {
    "nct_id": "NCT05129995",
    "title": "Passive Heat Treatment and Skeletal Muscle Reconditioning Older Adults",
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      "NA"
    ],
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      "Sarcopenia"
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      {
        "name": "Passive heat treatment",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Maastricht University Medical Center+, Maastricht, Limburg, Netherlands"
    ],
    "start_date": "2022-03-28",
    "completion_date": "2022-12-20",
    "last_update": "2023-05-03",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05129995"
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  {
    "nct_id": "NCT05237219",
    "title": "Heat Therapy in Patients With Type 2 Diabetes Mellitus",
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      "NA"
    ],
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      "Diabetes Mellitus, Type 2",
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        "name": "Passive heating",
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      {
        "name": "Thermoneutral",
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    ],
    "locations": [
      "Institute for Translational Medicine, University of Pécs, Pécs, Hungary"
    ],
    "start_date": "2022-05-01",
    "completion_date": "2024-06-01",
    "last_update": "2023-04-18",
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      "sleep-and-passive-heating"
    ],
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      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05237219"
  },
  {
    "nct_id": "NCT05799547",
    "title": "The Effect of Cold Application on Patient's Pain, Comfort and Satisfaction After Cesarean Section",
    "status": "UNKNOWN",
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      "NA"
    ],
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      "Pain"
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      {
        "name": "cold group",
        "type": "OTHER"
      }
    ],
    "locations": [],
    "start_date": "2023-06-20",
    "completion_date": "2023-08-20",
    "last_update": "2023-04-04",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05799547"
  },
  {
    "nct_id": "NCT05805540",
    "title": "Effects on CK, RPE, VAS Scale and Physical Performance of Three Recovery Methods in Elite Basketball Players",
    "status": "COMPLETED",
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      "NA"
    ],
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      "Cold-water Immersion",
      "Protein-carbohydrates Supplementation",
      "Active Recovery",
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      {
        "name": "Cold-water immersion",
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      {
        "name": "Protein-carbohydrates supplementation",
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      },
      {
        "name": "Active recovery",
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      },
      {
        "name": "Placebo",
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      }
    ],
    "locations": [
      "Science of Education Faculty, Puerto Real, Cadiz, Spain"
    ],
    "start_date": "2017-02-01",
    "completion_date": "2017-03-28",
    "last_update": "2023-03-27",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05805540"
  },
  {
    "nct_id": "NCT03763357",
    "title": "Acute Effects of Leg Heating on Skeletal Muscle Blood Flow",
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      "NA"
    ],
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      "Peripheral Arterial Disease"
    ],
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      {
        "name": "Heat Therapy (HT)",
        "type": "DEVICE"
      }
    ],
    "locations": [],
    "start_date": "2022-07-01",
    "completion_date": "2022-12-31",
    "last_update": "2023-03-26",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03763357"
  },
  {
    "nct_id": "NCT04383080",
    "title": "The Effect and Safety of Low-level Laser Therapy in Acute Decompensated Heart Failure Patients.",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
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      "NA"
    ],
    "enrollment": 17,
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      "Heart Failure",
      "Acupuncture"
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      {
        "name": "Acupuncture",
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      },
      {
        "name": "Low-level laser therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "National Yang Ming University Hospital, Yilan, Taiwan"
    ],
    "start_date": "2020-07-01",
    "completion_date": "2022-12-17",
    "last_update": "2023-03-22",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04383080"
  },
  {
    "nct_id": "NCT05787912",
    "title": "Efficacy of Hyaluronic Acid Gel and Photobiomodulation on Wound Healing After Surgical Gingivectomy",
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      "NA"
    ],
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      "Gingival Enlargement"
    ],
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      {
        "name": "Photobiomodulation",
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      },
      {
        "name": "Hyaluronic acid after photobiomodulation",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Faculty of Dentistry, Alexandria University, Alexandria, Egypt"
    ],
    "start_date": "2022-02-01",
    "completion_date": "2023-02-10",
    "last_update": "2023-03-15",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05787912"
  },
  {
    "nct_id": "NCT05759975",
    "title": "Effectiveness of Extraoral Photobiomodulation in Management of Oral Adverse Effects in Patients Undergoing HSCT",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
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      "NA"
    ],
    "enrollment": 42,
    "conditions": [
      "Oral Mucositis",
      "Hematopoietic Neoplasm",
      "Xerostomia",
      "Hyposalivation"
    ],
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      {
        "name": "Photobiomodulation therapy (intraoral)",
        "type": "DEVICE"
      },
      {
        "name": "Photobiomodulation therapy (extraoral)",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil"
    ],
    "start_date": "2023-01-13",
    "completion_date": "2024-06-30",
    "last_update": "2023-03-07",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05759975"
  },
  {
    "nct_id": "NCT05211076",
    "title": "The Effect of Music Practice and Marmet Technique on Lactation and Maternal Anxiety in Mothers With Premature Babies",
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      "NA"
    ],
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      "Lactation"
    ],
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      {
        "name": "Music Group",
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      },
      {
        "name": "Marmet Technique Group",
        "type": "OTHER"
      },
      {
        "name": "Control group",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Prof. Dr. Süleyman Yalçın City Hospital, Istanbul, Turkey (Türkiye)"
    ],
    "start_date": "2024-01-08",
    "completion_date": "2025-02",
    "last_update": "2023-03-07",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05211076"
  },
  {
    "nct_id": "NCT05757518",
    "title": "Post-exercise Recovery of DOMS in Recreational Athletes",
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      "NA"
    ],
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      "Injury;Sports"
    ],
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      {
        "name": "Cryosauna",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Physical Exercise Laboratory, Gdansk, Poland"
    ],
    "start_date": "2023-01-16",
    "completion_date": "2023-01-31",
    "last_update": "2023-03-03",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05757518"
  },
  {
    "nct_id": "NCT05677698",
    "title": "Menoupausal Symptoms and Aromatherapy",
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      "NA"
    ],
    "enrollment": 90,
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      "Aromatherapy"
    ],
    "interventions": [
      {
        "name": "Lemon oil",
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      },
      {
        "name": "peppermint oil",
        "type": "OTHER"
      },
      {
        "name": "Almond oil",
        "type": "OTHER"
      }
    ],
    "locations": [
      "KTO Karatay University, Konya, Turkey (Türkiye)"
    ],
    "start_date": "2022-12-27",
    "completion_date": "2023-02-27",
    "last_update": "2023-02-27",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05677698"
  },
  {
    "nct_id": "NCT02723604",
    "title": "Low-Level Laser Therapy for Prevention of Oral Mucositis",
    "status": "COMPLETED",
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      "NA"
    ],
    "enrollment": 25,
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      "Mucositis"
    ],
    "interventions": [
      {
        "name": "Low Level Laser Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Wayne State University/Karmanos Cancer Institute, Detroit, Michigan, United States"
    ],
    "start_date": "2016-03",
    "completion_date": "2021-09-13",
    "last_update": "2023-02-23",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02723604"
  },
  {
    "nct_id": "NCT04249700",
    "title": "Investigating the Effect of Single-session Sauna Use on Body Temperature",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
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      "NA"
    ],
    "enrollment": 25,
    "conditions": [
      "Core Body Temperature 101.3 F"
    ],
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      {
        "name": "Curve Sauna Dome",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "University of California San Francisco, San Francisco, California, United States"
    ],
    "start_date": "2019-09-13",
    "completion_date": "2020-04-01",
    "last_update": "2023-01-31",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04249700"
  },
  {
    "nct_id": "NCT05255055",
    "title": "Effectiveness of Therapeutic Exercise Versus Manual Therapy in Patients With Chronic Neck Pain",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Chronic Neck Pain"
    ],
    "interventions": [
      {
        "name": "Physical Therapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Alcala, Alcalá de Henares, Madrid, Spain"
    ],
    "start_date": "2022-01-12",
    "completion_date": "2022-12-23",
    "last_update": "2022-12-24",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05255055"
  },
  {
    "nct_id": "NCT05062148",
    "title": "Fundamental and Applied Concussion Recovery Modality Research and Development: Applications for the Enhanced Recovery",
    "status": "WITHDRAWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 0,
    "conditions": [
      "Traumatic Brain Injury",
      "Post-Concussion Syndrome",
      "Concussion, Brain"
    ],
    "interventions": [
      {
        "name": "Float-REST",
        "type": "OTHER"
      },
      {
        "name": "Photobiomodulation",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Rockefeller Neuroscience Institute at West Virginia University, Morgantown, West Virginia, United States"
    ],
    "start_date": "2021-09",
    "completion_date": "2022-06-07",
    "last_update": "2022-12-21",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05062148"
  },
  {
    "nct_id": "NCT01421290",
    "title": "Treatment of Cartilage Lesions in Flanders Today",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Lesion of Joint Capsule of Knee Region"
    ],
    "interventions": [
      {
        "name": "Surgery",
        "type": "PROCEDURE"
      },
      {
        "name": "Conservative comparator",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University Hospital, Ghent, Ghent, Belgium"
    ],
    "start_date": "2013-01",
    "completion_date": "2015-12",
    "last_update": "2022-12-13",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01421290"
  },
  {
    "nct_id": "NCT05584527",
    "title": "Assessment of the Effects of a 24-hour Cold and Heat Exposure on the Factors Influencing Food Intake",
    "status": "UNKNOWN",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 24,
    "conditions": [
      "Eating Habit",
      "Cold Exposure",
      "Heat"
    ],
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      {
        "name": "Heat exposure (32°C)",
        "type": "OTHER"
      },
      {
        "name": "Cold exposure (16°C)",
        "type": "OTHER"
      },
      {
        "name": "Thermoneutral exposure (24°C)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Institut de Recherche Biomédicale des Armées, Brétigny-sur-Orge, France"
    ],
    "start_date": "2022-11-28",
    "completion_date": "2025-05",
    "last_update": "2022-12-08",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05584527"
  },
  {
    "nct_id": "NCT05590754",
    "title": "50% Body Weight Reverses Stature, Lumbar Disc Expansion and Vertebral Compliance by Hyper-Buoyancy Floatation.",
    "status": "COMPLETED",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 16,
    "conditions": [
      "Intervertebral Disc Compression",
      "Muscle Atrophy",
      "Spine Injury"
    ],
    "interventions": [
      {
        "name": "Hyper-buoyancy Floatation (HBF)",
        "type": "DEVICE"
      },
      {
        "name": "Axial Load after 4h of HBF",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Universidad Autónoma de Madrid, Madrid, Spain",
      "King's College London, London, United Kingdom"
    ],
    "start_date": "2018-06-12",
    "completion_date": "2022-03-01",
    "last_update": "2022-12-03",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05590754"
  },
  {
    "nct_id": "NCT05428644",
    "title": "Effect of Reflexology Massage on Pain and Anxiety.",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 48,
    "conditions": [
      "Pain",
      "Anxiety"
    ],
    "interventions": [
      {
        "name": "massage therapy",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Dokuz Eylül University, Balçova, İzmir, Turkey (Türkiye)"
    ],
    "start_date": "2022-02-10",
    "completion_date": "2022-10-10",
    "last_update": "2022-11-14",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05428644"
  },
  {
    "nct_id": "NCT04961151",
    "title": "Working Toward the Advancement of Recovery Using Modulated Therapeutic Hyperthermia (WARMTH) in Sepsis - Pilot",
    "status": "WITHDRAWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 0,
    "conditions": [
      "Sepsis"
    ],
    "interventions": [
      {
        "name": "Multimodal therapeutic warming w/ esophageal d/c",
        "type": "OTHER"
      },
      {
        "name": "Multimodal therapeutic warming w/ conductive d/c",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States",
      "Hennepin County Medical Center, Minneapolis, Minnesota, United States",
      "Washington University, St Louis, Missouri, United States"
    ],
    "start_date": "2021-08-25",
    "completion_date": "2022-07-01",
    "last_update": "2022-11-08",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04961151"
  },
  {
    "nct_id": "NCT04588103",
    "title": "Artery Function Responses to Heat Therapy and Exercise Training",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Endothelial Dysfunction"
    ],
    "interventions": [
      {
        "name": "Heat therapy",
        "type": "OTHER"
      },
      {
        "name": "Exercise training",
        "type": "OTHER"
      }
    ],
    "locations": [
      "McMaster University Vascular Dynamics Lab, Hamilton, Ontario, Canada"
    ],
    "start_date": "2021-07-13",
    "completion_date": "2022-06-18",
    "last_update": "2022-11-08",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04588103"
  },
  {
    "nct_id": "NCT00214851",
    "title": "The Use of Kineret (Anakinra) in the Treatment of Familial Cold Urticaria",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 8,
    "conditions": [
      "Familial Cold Urticaria"
    ],
    "interventions": [
      {
        "name": "Kineret (anakinra)",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Queen Elizabeth Health Sciences Centre, Halifax, Nova Scotia, Canada"
    ],
    "start_date": "2005-09",
    "completion_date": "2005-12",
    "last_update": "2022-11-04",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00214851"
  },
  {
    "nct_id": "NCT04320563",
    "title": "Rexon-Eye in Dry Eye",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Dry Eye"
    ],
    "interventions": [
      {
        "name": "Rexon-eye",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Singapore Eye Research Institute, Singapore, Singapore"
    ],
    "start_date": "2019-07-20",
    "completion_date": "2022-08-30",
    "last_update": "2022-10-25",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04320563"
  },
  {
    "nct_id": "NCT05595564",
    "title": "Influence of PBM on Anaerobic Capacity Under Normoxia and Hypoxia",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 7,
    "conditions": [
      "Low Level Laser Therapy",
      "Photobiomodulation",
      "Performance",
      "Sport"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "University of Sao Paulo, Ribeirão Preto, São Paulo, Brazil"
    ],
    "start_date": "2021-08-31",
    "completion_date": "2022-12-31",
    "last_update": "2022-10-21",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05595564"
  },
  {
    "nct_id": "NCT05542654",
    "title": "The Effect of Foot Massage on Blood Pressure and Anxiety Levels in Pregnants With Hypertension",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 80,
    "conditions": [
      "Pre-Eclampsia",
      "Gestational Hypertension",
      "Chronic Hypertension With Pre-Eclampsia",
      "Superimposed Pre-Eclampsia"
    ],
    "interventions": [
      {
        "name": "Foot Massage",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Bakırkoy Training and Research Hospital, Istanbul, Turkey (Türkiye)"
    ],
    "start_date": "2020-11-05",
    "completion_date": "2022-02-15",
    "last_update": "2022-09-13",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05542654"
  },
  {
    "nct_id": "NCT05507619",
    "title": "Heat and Acupuncture Randomised Controlled Trial to Manage Osteoarthritis of the Knee",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 173,
    "conditions": [
      "Osteoarthritis, Knee"
    ],
    "interventions": [
      {
        "name": "Acupuncture with Heat Therapy + Standard Care",
        "type": "OTHER"
      },
      {
        "name": "Standard Care",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Singapore Chung Hwa Medical Institution, Singapore, Singapore",
      "Tan Tock Seng Hospital, Singapore, Singapore"
    ],
    "start_date": "2022-08-17",
    "completion_date": "2024-07-31",
    "last_update": "2022-08-17",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05507619"
  },
  {
    "nct_id": "NCT05474443",
    "title": "Comparison of Instrument Assisted Soft Tissue Mobilization and Myofascial Gun in Upper Cross Syndrome",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Postural; Defect"
    ],
    "interventions": [
      {
        "name": "Myofascial gun with conventional therapy",
        "type": "OTHER"
      },
      {
        "name": "Instrument Assisted Soft Tissue Mobilization with Conventional therapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Pakistan Railway General Hospital, Rawalpindi, Punjab Province, Pakistan"
    ],
    "start_date": "2021-11-25",
    "completion_date": "2022-07-10",
    "last_update": "2022-07-25",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05474443"
  },
  {
    "nct_id": "NCT04613843",
    "title": "Cold Water Immersion Stirring in Hyperthermic Individuals",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 16,
    "conditions": [
      "Hyperthermia"
    ],
    "interventions": [
      {
        "name": "Water Stirring",
        "type": "OTHER"
      },
      {
        "name": "No Water Stirring",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Center for Research and Exercise in Special Environments, Buffalo, New York, United States"
    ],
    "start_date": "2019-10-23",
    "completion_date": "2022-05-01",
    "last_update": "2022-07-22",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04613843"
  },
  {
    "nct_id": "NCT05413993",
    "title": "Effect of Photobiomodulation on ph and Salivary Flow",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 20,
    "conditions": [
      "Xerostomia"
    ],
    "interventions": [
      {
        "name": "photobiomodulation",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "Nove de Julho Univ, São Paulo, São Paulo, Brazil"
    ],
    "start_date": "2022-03-10",
    "completion_date": "2022-05-20",
    "last_update": "2022-06-07",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05413993"
  },
  {
    "nct_id": "NCT03113123",
    "title": "Prevention of HIV in \"Île-de-France\"",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 3257,
    "conditions": [
      "HIV Infections"
    ],
    "interventions": [
      {
        "name": "PrEP with Truvada®",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Hôpital Avicenne, Bobigny, France",
      "Hôpital Jean Verdier, Bondy, France",
      "Hôpital Ambroise-Paré, Boulogne, France",
      "Hôpital Antoine Béclère, Clamart, France",
      "Hôpital Louis Mourier, Colombes, France",
      "Hôpital Henry Mondor, Créteil, France",
      "Hôpital Raymond Poincaré, Garches, France",
      "Hôpital de Bicêtre, Le Kremlin-Bicêtre, France"
    ],
    "start_date": "2017-05-03",
    "completion_date": "2024-10",
    "last_update": "2022-06-01",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03113123"
  },
  {
    "nct_id": "NCT04915859",
    "title": "Semiconductor Heat Extraction Cooling",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 24,
    "conditions": [
      "Hyperthermia"
    ],
    "interventions": [
      {
        "name": "Hand Cooling at 12-15 degrees celsius",
        "type": "OTHER"
      },
      {
        "name": "Hand Cooling at 16-20 degrees celsius",
        "type": "OTHER"
      },
      {
        "name": "hand and back cooling at 12-15 or 16-20 degrees celsius",
        "type": "OTHER"
      },
      {
        "name": "Passive cooling",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Korey Stringer Institute, University of Connecticut, Storrs, Connecticut, United States"
    ],
    "start_date": "2021-10-04",
    "completion_date": "2022-01-31",
    "last_update": "2022-05-27",
    "topics": [
      "cold-water-immersion",
      "exercise-recovery"
    ],
    "topic_names": [
      "Cold-Water Immersion",
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04915859"
  },
  {
    "nct_id": "NCT05392153",
    "title": "The Effect of Myofascial Release Technique on Sportive Performance, Balance and Injury Risk in Runners",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 49,
    "conditions": [
      "Runt"
    ],
    "interventions": [
      {
        "name": "Myofascial therapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Backtofit, Istanbul, Sarıyer, Turkey (Türkiye)"
    ],
    "start_date": "2021-09-01",
    "completion_date": "2022-09-01",
    "last_update": "2022-05-20",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05392153"
  },
  {
    "nct_id": "NCT05076357",
    "title": "Cold, Appetite and Weight Loss in Individuals With Obesity",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 78,
    "conditions": [
      "Weight Loss",
      "Cold Exposure",
      "Appetitive Behavior"
    ],
    "interventions": [
      {
        "name": "Caloric Restriction",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Cold intervention",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Ottawa, Ottawa, Ontario, Canada"
    ],
    "start_date": "2022-02-01",
    "completion_date": "2024-10-31",
    "last_update": "2022-04-19",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05076357"
  },
  {
    "nct_id": "NCT04183673",
    "title": "Laser + Cryo-thermal Therapy Following Total Knee Replacement Surgery",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 68,
    "conditions": [
      "Knee Arthropathy"
    ],
    "interventions": [
      {
        "name": "Laser therapy-cryo thermal therapy",
        "type": "PROCEDURE"
      },
      {
        "name": "Usual care",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "ICS Maugeri, Montescano Rehabilitation Center, Montescano, Pavia, Italy"
    ],
    "start_date": "2018-05-29",
    "completion_date": "2019-02-28",
    "last_update": "2022-03-31",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04183673"
  },
  {
    "nct_id": "NCT05296200",
    "title": "Cervical Changes by 4h of Hyper-buoyancy Flotation and Followed by 15 Mins 1g Re-loading",
    "status": "COMPLETED",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 12,
    "conditions": [
      "Intervertebral Disc Herniation",
      "Stiffness; Spine"
    ],
    "interventions": [
      {
        "name": "Hyperbuoyancy Floatation",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "CSEU-Lasalle, Madrid, Spain"
    ],
    "start_date": "2020-03-13",
    "completion_date": "2022-02-10",
    "last_update": "2022-03-24",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05296200"
  },
  {
    "nct_id": "NCT02609724",
    "title": "Effectiveness of Fluoroscopy-guided MLD for Treatment of BCRL",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 194,
    "conditions": [
      "Breast Neoplasm",
      "Lymphedema"
    ],
    "interventions": [
      {
        "name": "Information",
        "type": "OTHER"
      },
      {
        "name": "Skin care",
        "type": "OTHER"
      },
      {
        "name": "Compression therapy",
        "type": "OTHER"
      },
      {
        "name": "Fluoroscopy-guided MLD",
        "type": "OTHER"
      },
      {
        "name": "Traditional MLD",
        "type": "OTHER"
      },
      {
        "name": "Placebo MLD",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Antwerp University Hospital, Antwerp, Belgium",
      "Centre Hospitalier Universitaire (CHU) Sint-Pieter, Lymphoedema Clinic, Brussels, Belgium",
      "University Hospitals of Leuven, lymphovenous center, Leuven, Belgium"
    ],
    "start_date": "2016-01",
    "completion_date": "2020-09",
    "last_update": "2022-03-08",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02609724"
  },
  {
    "nct_id": "NCT04788329",
    "title": "The Effect of Mindfulness Programs on Postoperative Pain",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 23,
    "conditions": [
      "Post Operative Pain"
    ],
    "interventions": [
      {
        "name": "\"Prepare for Surgery, Heal Faster\" Program",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Wim Hof Method",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "NYUSoM, New York, New York, United States"
    ],
    "start_date": "2021-02-15",
    "completion_date": "2022-03-01",
    "last_update": "2022-03-07",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04788329"
  },
  {
    "nct_id": "NCT05270187",
    "title": "Multiwave Locked System Laser for Patients With Bell's Palsy.",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Facial Paralyses, Idiopathic",
      "Laser Therapy",
      "Bell Palsy"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation therapy (laser therapy)",
        "type": "OTHER"
      },
      {
        "name": "Facial massage and facial expression exercises",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Umm Al-Qura University, Faculty of Applied Medical Science, Mecca, Saudi Arabia"
    ],
    "start_date": "2022-01-10",
    "completion_date": "2022-04",
    "last_update": "2022-03-06",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05270187"
  },
  {
    "nct_id": "NCT05279911",
    "title": "Effect of Low-level Laser Therapy on Type II Controlled Diabetic Patients After Dental Implant Insertion",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "T2DM (Type 2 Diabetes Mellitus)",
      "Low-level Laser Therapy",
      "Bone Density Increased"
    ],
    "interventions": [
      {
        "name": "low-level laser therapy (LLLT)",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, Egypt",
      "Misr International University, Cairo, Egypt",
      "Misr University for Science and Technology (MUST), Cairo, Egypt",
      "Sinai University, El Arish, Egypt",
      "Delta University of Science and Technology, Gamasa, Egypt"
    ],
    "start_date": "2021-03-03",
    "completion_date": "2022-01-22",
    "last_update": "2022-03-05",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05279911"
  },
  {
    "nct_id": "NCT03911830",
    "title": "Aerobic Exercise Program Followed by Cold Water Immersion: Effects on Arthritis Patients Arterial Stiffness",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 18,
    "conditions": [
      "Rheumatoid Arthritis",
      "Cryotherapy Effect",
      "Physical Activity"
    ],
    "interventions": [
      {
        "name": "Exercise followed cold water immersion",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Clément Prati, Besançon, France"
    ],
    "start_date": "2017-11-11",
    "completion_date": "2019-03-06",
    "last_update": "2022-02-23",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03911830"
  },
  {
    "nct_id": "NCT03416998",
    "title": "Photobiomodulation On Muscle Recovery In Professional Soccer Players",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Muscle Development"
    ],
    "interventions": [
      {
        "name": "phototherapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Nove de Julho, São Paulo, Brazil"
    ],
    "start_date": "2016-03-03",
    "completion_date": "2018-02-10",
    "last_update": "2022-02-18",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03416998"
  },
  {
    "nct_id": "NCT05191043",
    "title": "Effects of Kinesio Taping in Addition to Routine Physical Therapy on Pain, Range of Motion and Functional Disability in Patients With Upper Cross Syndrome",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 68,
    "conditions": [
      "Cervical Pain"
    ],
    "interventions": [
      {
        "name": "Kinesio Taping Technique",
        "type": "OTHER"
      },
      {
        "name": "Routine Physical Therapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Waqar Afzal, Lahore, Punjab Province, Pakistan"
    ],
    "start_date": "2021-11-24",
    "completion_date": "2022-02-05",
    "last_update": "2022-02-06",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05191043"
  },
  {
    "nct_id": "NCT05225519",
    "title": "Effects of Far Infrared Radiation on Fibromyalgia Patients",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 16,
    "conditions": [
      "Fibromyalgia"
    ],
    "interventions": [
      {
        "name": "long-sleeved white shirt impregnated with a long-infrared irradiation",
        "type": "DEVICE"
      },
      {
        "name": "long-sleeved white shirt",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "2CA-Braga, Braga, Portugal"
    ],
    "start_date": "2018-03-26",
    "completion_date": "2019-08-27",
    "last_update": "2022-02-01",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05225519"
  },
  {
    "nct_id": "NCT04762238",
    "title": "Does the Diacutaneous Fibrolysis Change Ultrasonographic Measurements in Patients With Carpal Tunnel Syndrome?",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Carpal Tunnel Syndrome",
      "Physical Therapy Modalities",
      "Ultrasonography"
    ],
    "interventions": [
      {
        "name": "Diacutaneous Fibrolysis",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Sandra Jiménez Jiménez-del-Barrio, Soria, Spain"
    ],
    "start_date": "2021-02-10",
    "completion_date": "2021-07-10",
    "last_update": "2022-01-14",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04762238"
  },
  {
    "nct_id": "NCT04516018",
    "title": "Shivering and Glucose Homeostasis",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 15,
    "conditions": [
      "Healthy Overweight/Obese"
    ],
    "interventions": [
      {
        "name": "Cold exposure",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Maastricht University, Maastricht, Limburg, Netherlands"
    ],
    "start_date": "2020-09-01",
    "completion_date": "2021-12-13",
    "last_update": "2022-01-13",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04516018"
  },
  {
    "nct_id": "NCT05191511",
    "title": "Assessment of Safety Distance of Far-Infrared Therapeutic Device to Human Skin",
    "status": "COMPLETED",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 24,
    "conditions": [
      "Far- Infrared Burn"
    ],
    "interventions": [
      {
        "name": "Far- infrared",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "Tainan Hospital, Ministry of Health and Welfare, Tainan, West Central Dist, Taiwan"
    ],
    "start_date": "2019-03-04",
    "completion_date": "2019-12-31",
    "last_update": "2022-01-02",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05191511"
  },
  {
    "nct_id": "NCT01209767",
    "title": "Cryolipolysis and Subcision for Treatment of Cellulite",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 22,
    "conditions": [
      "Cellulite"
    ],
    "interventions": [
      {
        "name": "cryolipolysis",
        "type": "DEVICE"
      },
      {
        "name": "Subcision",
        "type": "PROCEDURE"
      },
      {
        "name": "Control",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Northwestern University Feinberg School of Medicine, Department of Dermatology, Chicago, Illinois, United States"
    ],
    "start_date": "2010-10",
    "completion_date": "2011-09",
    "last_update": "2021-12-01",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01209767"
  },
  {
    "nct_id": "NCT05142852",
    "title": "Shock Wave Therapy in Individuals With Lateral Epicondylitis",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 43,
    "conditions": [
      "Lateral Epicondylitis"
    ],
    "interventions": [
      {
        "name": "Extracorporeal shock wave therapy",
        "type": "DEVICE"
      },
      {
        "name": "Conventional physiotherapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Isra University, Amman, Jordan"
    ],
    "start_date": "2021-06-05",
    "completion_date": "2021-09-04",
    "last_update": "2021-11-22",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05142852"
  },
  {
    "nct_id": "NCT05099406",
    "title": "Home-based Transcranial Stimulation in the Treatment of Patients With Refractory Chronic Pain",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 120,
    "conditions": [
      "Chronic Pain"
    ],
    "interventions": [
      {
        "name": "Transcranial electrical stimulation",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain"
    ],
    "start_date": "2022-01-01",
    "completion_date": "2023-05-01",
    "last_update": "2021-10-18",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05099406"
  },
  {
    "nct_id": "NCT05094921",
    "title": "Halliwick Concept on Motor Functions in Spastic CP",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 36,
    "conditions": [
      "Spastic Cerebral Palsy",
      "Spastic Hemiplegic Cerebral Palsy"
    ],
    "interventions": [
      {
        "name": "Aquatic Halliwick method",
        "type": "OTHER"
      },
      {
        "name": "Conventional physical therapy",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "October 6 University Hospital, Al Ḩayy Ath Thāmin, Giza Governorate, Egypt"
    ],
    "start_date": "2021-06-01",
    "completion_date": "2021-09-08",
    "last_update": "2021-10-15",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT05094921"
  },
  {
    "nct_id": "NCT04404231",
    "title": "Treatment of Intrapartum Depression Using Non-invasive Photobiomodulation",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 80,
    "conditions": [
      "Depression",
      "Pregnancy Related",
      "Intrapartum Depression"
    ],
    "interventions": [
      {
        "name": "Delivery of infrared light to the head",
        "type": "RADIATION"
      },
      {
        "name": "No Infrared treatment",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Detroit Medical Ceter, Detroit, Michigan, United States"
    ],
    "start_date": "2021-11-01",
    "completion_date": "2022-09-01",
    "last_update": "2021-10-04",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04404231"
  },
  {
    "nct_id": "NCT04257266",
    "title": "Cryo Pack Cooling After Exercise-induced Hyperthermia",
    "status": "WITHDRAWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 0,
    "conditions": [
      "Hyperthermia"
    ],
    "interventions": [
      {
        "name": "Ice Pack Cooling",
        "type": "DEVICE"
      }
    ],
    "locations": [],
    "start_date": "2021-02-01",
    "completion_date": "2021-07-15",
    "last_update": "2021-09-28",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04257266"
  },
  {
    "nct_id": "NCT03015116",
    "title": "Photobiomodulation for Plantar Fasciitis",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 114,
    "conditions": [
      "Plantar Fascitis"
    ],
    "interventions": [
      {
        "name": "Stretching",
        "type": "OTHER"
      },
      {
        "name": "Cryotherapy",
        "type": "OTHER"
      },
      {
        "name": "Photobiomodulation Low Power",
        "type": "DEVICE"
      },
      {
        "name": "Photobiomodulation High Power",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Landstuhl Regional Medical Center, Landstuhl, APO AE, Germany"
    ],
    "start_date": "2017-01-12",
    "completion_date": "2020-02-28",
    "last_update": "2021-09-18",
    "topics": [
      "exercise-recovery",
      "photobiomodulation"
    ],
    "topic_names": [
      "Exercise Recovery",
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03015116"
  },
  {
    "nct_id": "NCT04716049",
    "title": "Effectiveness of Recovery Protocols in Elite Professional Young Soccer Players",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 20,
    "conditions": [
      "Soccer",
      "Physical Stress",
      "Fatigue"
    ],
    "interventions": [
      {
        "name": "Powerade©, CHP, CJ, FR, CWI",
        "type": "OTHER"
      },
      {
        "name": "Powerade©, CHP, STR, ICWI",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Universitat de Vic-Universitat Central de Catalunya, Vic, Barcelona, Spain"
    ],
    "start_date": "2021-09-03",
    "completion_date": "2021-09-06",
    "last_update": "2021-09-08",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04716049"
  },
  {
    "nct_id": "NCT03924011",
    "title": "Photobiomodulation Therapy for the Prevention of Acute Radiodermatitis in Breast Cancer Patients Undergoing Radiotherapy",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 71,
    "conditions": [
      "Radiodermatitis",
      "Breast Cancer"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation therapy (PBMT)",
        "type": "DEVICE"
      },
      {
        "name": "Sham laser",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Ziekenhuis Oost-Limburg Campus St.-Jan, Genk, Limburg, Belgium",
      "Jessa Ziekenhuis, Hasselt, Belgium"
    ],
    "start_date": "2020-07-01",
    "completion_date": "2021-06-01",
    "last_update": "2021-08-31",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03924011"
  },
  {
    "nct_id": "NCT03878420",
    "title": "Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITE II)",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 44,
    "conditions": [
      "Dry Age-related Macular Degeneration"
    ],
    "interventions": [
      {
        "name": "Valeda PBM treatment",
        "type": "DEVICE"
      },
      {
        "name": "Valeda Sham treatment",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Institut ophtalmologique de l'Ouest- Clinique jules VERNE, Nantes, France",
      "Universitätsklinikum Freiburg- Klinik für Augenheilkunde, Freiburg im Breisgau, Germany",
      "Klinik fur Ophthalmologie, Universitatsklinikum Schleswig-Holstein, Kiel, Germany",
      "Universitaetsmedizin Mainz- Augenklinik, Mainz, Germany",
      "Osprdalr San Raffaele, Milan, Italy",
      "Institut Català de Retina, Barcelona, Spain",
      "James Paget University, Great Yarmouth, United Kingdom",
      "Peterborough City Hospital, Peterborough, United Kingdom"
    ],
    "start_date": "2019-02-14",
    "completion_date": "2021-01-22",
    "last_update": "2021-08-31",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03878420"
  },
  {
    "nct_id": "NCT04059809",
    "title": "Photobiomodulation for Breast Cancer Radiodermatitis",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE2",
      "PHASE3"
    ],
    "enrollment": 48,
    "conditions": [
      "Breast Cancer",
      "Radiodermatitis",
      "Radiotherapy Side Effect",
      "Radiation Dermatitis",
      "Radiation Toxicity",
      "Radiation Injuries",
      "Quality of Life",
      "Breast Neoplasms"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Universidade do Vale do Itajai - UNIVALI, Itajaí, Santa Catarina, Brazil"
    ],
    "start_date": "2018-09-26",
    "completion_date": "2021-07-20",
    "last_update": "2021-08-11",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04059809"
  },
  {
    "nct_id": "NCT04415307",
    "title": "The Efficacy and Safety of Traditional Chinese Medicine (TCM) to the Patient With Dizziness in Emergency Department",
    "status": "WITHDRAWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 0,
    "conditions": [
      "Dizziness"
    ],
    "interventions": [
      {
        "name": "Acupuncture",
        "type": "OTHER"
      },
      {
        "name": "Far-Infrared heat-patch attachment",
        "type": "OTHER"
      },
      {
        "name": "Acupuncture and Fir-Infrared heat-patch attachment",
        "type": "OTHER"
      },
      {
        "name": "Far-Infrared heat-patch attachment over acupoints without electric current passing.",
        "type": "OTHER"
      }
    ],
    "locations": [],
    "start_date": "2020-12-01",
    "completion_date": "2021-08-03",
    "last_update": "2021-08-03",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04415307"
  },
  {
    "nct_id": "NCT04747938",
    "title": "Frozen Shoulder Treated by Energy Accumulator",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 38,
    "conditions": [
      "Frozen Shoulder"
    ],
    "interventions": [
      {
        "name": "Energy accumulator",
        "type": "DEVICE"
      },
      {
        "name": "Home exercise program",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [],
    "start_date": "2014-09-01",
    "completion_date": "2015-10-24",
    "last_update": "2021-07-30",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04747938"
  },
  {
    "nct_id": "NCT04934709",
    "title": "Photobiomodulation Therapy Combined With Static Magnetic Field on the Subsequent Performance",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 12,
    "conditions": [
      "Skeletal Muscle Performance"
    ],
    "interventions": [
      {
        "name": "Active PBMT-sMF",
        "type": "DEVICE"
      },
      {
        "name": "Placebo PBMT-sMF",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Laboratory of Phototherapy and Innovative Technologies in Health, São Paulo, Brazil"
    ],
    "start_date": "2015-05",
    "completion_date": "2015-09",
    "last_update": "2021-06-18",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04934709"
  },
  {
    "nct_id": "NCT04698200",
    "title": "Type 2 Diabetes, Cardiovascular Comorbidity and Environmental Temperature",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 20,
    "conditions": [
      "Type 2 Diabetes"
    ],
    "interventions": [
      {
        "name": "Cold exposure",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Oulu, Center for Environmental and Respiratory Health Research, Oulu, Finland"
    ],
    "start_date": "2021-01-01",
    "completion_date": "2023-12",
    "last_update": "2021-06-17",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04698200"
  },
  {
    "nct_id": "NCT04417738",
    "title": "Transcranial Photobiomodulation for the Treatment of Opioid Cravings",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 22,
    "conditions": [
      "Opioid-use Disorder",
      "Depression, Anxiety",
      "Craving"
    ],
    "interventions": [
      {
        "name": "unilateral transcranial photobiomodulation, near infrared mode",
        "type": "DEVICE"
      },
      {
        "name": "Sham treatment",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "MindLight, LLC, Newton Highlands, Massachusetts, United States"
    ],
    "start_date": "2019-07-01",
    "completion_date": "2019-11-15",
    "last_update": "2021-05-22",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04417738"
  },
  {
    "nct_id": "NCT04897555",
    "title": "LLLT for Alopecia of the Eyebrow in Women",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Alopecia"
    ],
    "interventions": [
      {
        "name": "LLLT",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "NST Consultants, Inc., Mendham, New Jersey, United States",
      "Bodian Dermatology, Great Neck, New York, United States"
    ],
    "start_date": "2019-05-01",
    "completion_date": "2019-10-01",
    "last_update": "2021-05-18",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04897555"
  },
  {
    "nct_id": "NCT04584437",
    "title": "Treatment of Covid-19 Infections Using Vitality Therapy or the Bible Cure",
    "status": "WITHDRAWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 0,
    "conditions": [
      "Covid-19 Infections"
    ],
    "interventions": [
      {
        "name": "Infrared Energy and Dietary Supplement",
        "type": "OTHER"
      }
    ],
    "locations": [
      "GAAD Medical Research Institute Inc. O/A The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2021-05-25",
    "completion_date": "2022-07-10",
    "last_update": "2021-05-13",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04584437"
  },
  {
    "nct_id": "NCT00762307",
    "title": "Non-invasive Cooling of Subcutaneous Fat",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Fat Disorder"
    ],
    "interventions": [
      {
        "name": "Zeltiq Dermal Cooling Device",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Investigational Site, Dublin, California, United States",
      "Investigational Site, Fremont, California, United States",
      "Investigational Site, Pleasanton, California, United States",
      "Investigational Site, San Ramon, California, United States"
    ],
    "start_date": "2007-01",
    "completion_date": "2012-01",
    "last_update": "2021-05-13",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00762307"
  },
  {
    "nct_id": "NCT04375969",
    "title": "Short to Long Effects of Whole Body Cryostimulation on Insulin Sensitivity Among Overweight",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 80,
    "conditions": [
      "Cryotherapy",
      "Training",
      "Overweight",
      "Insulin"
    ],
    "interventions": [
      {
        "name": "whole body cryostimulation treatment",
        "type": "OTHER"
      },
      {
        "name": "Connection WBC treatment and HIIT training",
        "type": "OTHER"
      },
      {
        "name": "Control Group",
        "type": "OTHER"
      },
      {
        "name": "HIIT training group",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Ziemann Ewa, Sopot, Pomeranian Voivodeship, Poland"
    ],
    "start_date": "2018-01-03",
    "completion_date": "2021-12-30",
    "last_update": "2021-05-07",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04375969"
  },
  {
    "nct_id": "NCT04201977",
    "title": "Comparison of Different Forms of Recovery on the Functionality After Physical Exercise",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 50,
    "conditions": [
      "Massage",
      "Inflammatory Response",
      "Muscle, Skeletal",
      "Cryotherapy Effect",
      "Functional Disturbance"
    ],
    "interventions": [
      {
        "name": "Foam Roller Recovery",
        "type": "OTHER"
      },
      {
        "name": "Active recovery",
        "type": "OTHER"
      },
      {
        "name": "Immersion in cold water",
        "type": "OTHER"
      },
      {
        "name": "Passive recovery",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Luis Ulisses Signori, Santa Maria, Rio Grande do Sul, Brazil"
    ],
    "start_date": "2019-06-01",
    "completion_date": "2021-04-30",
    "last_update": "2021-04-30",
    "topics": [
      "cold-water-immersion",
      "exercise-recovery"
    ],
    "topic_names": [
      "Cold-Water Immersion",
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04201977"
  },
  {
    "nct_id": "NCT04673318",
    "title": "Physical Rehabilitation of COVID-19 Survivors by Heat Therapy",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 87,
    "conditions": [
      "Covid19",
      "Physical Disability"
    ],
    "interventions": [
      {
        "name": "heat therapy",
        "type": "BEHAVIORAL"
      },
      {
        "name": "exercise training",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Institute of Applied Life Sciences, Amherst, Massachusetts, United States"
    ],
    "start_date": "2021-02-26",
    "completion_date": "2024-12",
    "last_update": "2021-04-27",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04673318"
  },
  {
    "nct_id": "NCT03765151",
    "title": "The Effectiveness of Low-level Laser Therapy in Orthodontic Retention for Periodontal-compromised Patients",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 35,
    "conditions": [
      "Orthodontics",
      "Periodontal Diseases"
    ],
    "interventions": [
      {
        "name": "low-level laser therapy",
        "type": "DEVICE"
      },
      {
        "name": "orthodontic retention",
        "type": "OTHER"
      }
    ],
    "locations": [
      "The Prince Philip Dental Hospital, Hong Kong, Hong Kong"
    ],
    "start_date": "2018-10-01",
    "completion_date": "2020-12-01",
    "last_update": "2021-04-27",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03765151"
  },
  {
    "nct_id": "NCT04841733",
    "title": "Effectiveness of Recovery Protocols Combination in Soccer Players",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 20,
    "conditions": [
      "Soccer",
      "Physical Stress",
      "Fatigue"
    ],
    "interventions": [
      {
        "name": "Foam Roller (FR)",
        "type": "OTHER"
      },
      {
        "name": "Stretching (STR)",
        "type": "OTHER"
      },
      {
        "name": "Cold-Water Immersion (CWI)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Universitat de Vic-Universitat Central de Catalunya, Vic, Spain"
    ],
    "start_date": "2021-04-18",
    "completion_date": "2021-10",
    "last_update": "2021-04-18",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04841733"
  },
  {
    "nct_id": "NCT04406922",
    "title": "Circadian Rhythmicity in Cold-induced Thermogenesis",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 24,
    "conditions": [
      "Healthy",
      "Obese",
      "Glucose Intolerance"
    ],
    "interventions": [
      {
        "name": "Personalized cooling protocol",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Leiden University Medical Center, Leiden, Netherlands"
    ],
    "start_date": "2019-04-23",
    "completion_date": "2021-01-01",
    "last_update": "2021-04-14",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04406922"
  },
  {
    "nct_id": "NCT04633707",
    "title": "Adjunctive Bright Light Therapy for Patients With Depression",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 159,
    "conditions": [
      "Depressive Disorder",
      "Light Therapy"
    ],
    "interventions": [
      {
        "name": "adjunctive bright white light therapy in the morning",
        "type": "DEVICE"
      },
      {
        "name": "adjunctive bright white light therapy in the afternoon",
        "type": "DEVICE"
      },
      {
        "name": "adjunctive dim red light therapy in the afternoon",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Guangzhou Brain Hospital (Guangzhou Huiai Hospital), Guanzhou, Guangdong, China"
    ],
    "start_date": "2021-03",
    "completion_date": "2022-07",
    "last_update": "2021-03-21",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04633707"
  },
  {
    "nct_id": "NCT03972007",
    "title": "Effect of Light-emitting Diode (LED) Photobiomodulation Therapy on Muscular Fatigue in University Handball Athletes",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 32,
    "conditions": [
      "Muscular Injury"
    ],
    "interventions": [
      {
        "name": "Fotobiomodulation",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Universidade de São Paulo, Ribeirão Preto, São Paulo, Brazil"
    ],
    "start_date": "2019-05-18",
    "completion_date": "2021-10-01",
    "last_update": "2021-03-17",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03972007"
  },
  {
    "nct_id": "NCT04695561",
    "title": "Effects of Different Myofascial Release Techniques on Iliotibial Band Tightness",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 39,
    "conditions": [
      "Fascia Lata"
    ],
    "interventions": [
      {
        "name": "Self Myofascial Relaxation",
        "type": "OTHER"
      },
      {
        "name": "Instrument Assisted Soft Tissue Mobilization",
        "type": "OTHER"
      },
      {
        "name": "Only Exercise (Control)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Bayram Sönmez Ünüvar, Konya, Turkey (Türkiye)"
    ],
    "start_date": "2020-11-23",
    "completion_date": "2021-03-15",
    "last_update": "2021-03-16",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04695561"
  },
  {
    "nct_id": "NCT04587544",
    "title": "The Relationship Between Cold Water Immersion and the Progression in Gout Arthritis",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 76,
    "conditions": [
      "Gout Arthritis"
    ],
    "interventions": [
      {
        "name": "Cold Water Immersion",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Rendra, Tomohon, North Celebes, Indonesia"
    ],
    "start_date": "2019-07-01",
    "completion_date": "2021-01-31",
    "last_update": "2021-03-16",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04587544"
  },
  {
    "nct_id": "NCT01791114",
    "title": "The Effect of Brown Adipose Tissue Activation on Insulin Sensitivity in Humans",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 39,
    "conditions": [
      "Insulin Sensitivity",
      "Obesity"
    ],
    "interventions": [
      {
        "name": "Cold exposure",
        "type": "OTHER"
      },
      {
        "name": "Cold exposure plus propranolol",
        "type": "OTHER"
      },
      {
        "name": "Thermoneutral Conditions",
        "type": "OTHER"
      },
      {
        "name": "Cold water consumption",
        "type": "OTHER"
      },
      {
        "name": "Tepid water consumption",
        "type": "OTHER"
      },
      {
        "name": "Exercise",
        "type": "OTHER"
      },
      {
        "name": "Meal consumption",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Texas Medical Branch at Galveston, Galveston, Texas, United States"
    ],
    "start_date": "2012-01",
    "completion_date": "2018-12-30",
    "last_update": "2021-03-12",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01791114"
  },
  {
    "nct_id": "NCT03483064",
    "title": "Interferential Current in Lower Back",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 74,
    "conditions": [
      "Lower Back"
    ],
    "interventions": [
      {
        "name": "Interferential current",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Blanca de La Cruz Torres, Seville, Spain"
    ],
    "start_date": "2018-05-07",
    "completion_date": "2018-05-30",
    "last_update": "2021-03-05",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03483064"
  },
  {
    "nct_id": "NCT03886376",
    "title": "Systematic Massage on Swimming Athletes Performance",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 19,
    "conditions": [
      "Athletes"
    ],
    "interventions": [
      {
        "name": "Deep Massage",
        "type": "OTHER"
      },
      {
        "name": "Superficial Massage",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Sao Paulo State University, Presidente Prudente, São Paulo, Brazil"
    ],
    "start_date": "2019-03-25",
    "completion_date": "2019-05-18",
    "last_update": "2021-02-19",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03886376"
  },
  {
    "nct_id": "NCT04733209",
    "title": "Mobilization With Movement in Carpal Tunnel Syndrome.",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 45,
    "conditions": [
      "Pain, Chronic"
    ],
    "interventions": [
      {
        "name": "TENS, US, exercise",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Kırşehir Ahi Evran Üniversitesi, Kırşehir, İç Anadolu, Turkey (Türkiye)"
    ],
    "start_date": "2020-10-28",
    "completion_date": "2021-01-15",
    "last_update": "2021-01-30",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04733209"
  },
  {
    "nct_id": "NCT04594317",
    "title": "Effect of Low-level Laser Therapy Versus Calcium Hydroxide Intracanal Medication on Postoperative Pain and Substance P Levels in Patients With Symptomatic Apical Periodontitis",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 46,
    "conditions": [
      "Postoperative Pain",
      "Apical Periodontitis"
    ],
    "interventions": [
      {
        "name": "low level laser therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [],
    "start_date": "2021-02-01",
    "completion_date": "2022-06-01",
    "last_update": "2021-01-24",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04594317"
  },
  {
    "nct_id": "NCT03429348",
    "title": "Evaluation of Post-Exposure Sauna Treatment of Firefighters - A Pilot Study",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 28,
    "conditions": [
      "Post-fire Rehabilitation of Firefighters in Sauna"
    ],
    "interventions": [
      {
        "name": "Sauna Rehabilitation",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Arizona, Tucson, Arizona, United States"
    ],
    "start_date": "2018-04-04",
    "completion_date": "2020-02-28",
    "last_update": "2021-01-19",
    "topics": [
      "infrared-sauna",
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Infrared Sauna",
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03429348"
  },
  {
    "nct_id": "NCT02526277",
    "title": "A Study on the Use of the MMF07 Foot Massager and Heat Therapy Treatments for Restless Leg Syndrome",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 28,
    "conditions": [
      "Restless Legs Syndrome"
    ],
    "interventions": [
      {
        "name": "MMF07 Foot Massager",
        "type": "DEVICE"
      },
      {
        "name": "Heat Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Ohio State University, Columbus, Ohio, United States"
    ],
    "start_date": "2016-01-06",
    "completion_date": "2018-09-25",
    "last_update": "2021-01-08",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02526277"
  },
  {
    "nct_id": "NCT04700475",
    "title": "Effect of Low Level Laser Therapy on Prevention of Radiotherapy Induced Xerostomia in Cancer Patients.",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Head and Neck Cancer"
    ],
    "interventions": [
      {
        "name": "low level laser",
        "type": "DEVICE"
      },
      {
        "name": "citric acid solution",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Cairo university, Giza, Egypt"
    ],
    "start_date": "2020-09-04",
    "completion_date": "2021-02",
    "last_update": "2021-01-06",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04700475"
  },
  {
    "nct_id": "NCT03969940",
    "title": "Thermotherapy of Buruli Ulcer at Community Level in the Health District of Akonolinga",
    "status": "WITHDRAWN",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 0,
    "conditions": [
      "Buruli Ulcer"
    ],
    "interventions": [],
    "locations": [],
    "start_date": "2019-01-01",
    "completion_date": "2020-06-30",
    "last_update": "2020-12-17",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03969940"
  },
  {
    "nct_id": "NCT04651426",
    "title": "Use of a Non-medicated Plaster in Chronic Lumbar Back Pain.",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 54,
    "conditions": [
      "Back Pain"
    ],
    "interventions": [
      {
        "name": "The FIT Therapy patch (D. FENSTEC s.r.l. Altavilla Vicentina, Italy) is a medical device class 1",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Azienda Ospedaliera Universitaria Integrata, Verona, Italy"
    ],
    "start_date": "2019-08-01",
    "completion_date": "2019-10-30",
    "last_update": "2020-11-25",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04651426"
  },
  {
    "nct_id": "NCT04407702",
    "title": "Control of Pain Due to Dentin Hypersensitivity in Individuals With Molar-incisor Hypomineralization",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1",
      "PHASE2"
    ],
    "enrollment": 140,
    "conditions": [
      "Dentin Sensitivity",
      "Molar Incisor Hypomineralization"
    ],
    "interventions": [
      {
        "name": "Hygiene Instructions",
        "type": "OTHER"
      },
      {
        "name": "Sealant application",
        "type": "PROCEDURE"
      },
      {
        "name": "Low-level Laser",
        "type": "RADIATION"
      }
    ],
    "locations": [],
    "start_date": "2021-01-01",
    "completion_date": "2021-12-10",
    "last_update": "2020-11-25",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04407702"
  },
  {
    "nct_id": "NCT03584750",
    "title": "Floating for Chronic Pain",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 99,
    "conditions": [
      "Chronic Pain Syndrome"
    ],
    "interventions": [
      {
        "name": "Floating",
        "type": "OTHER"
      },
      {
        "name": "Placebo floating",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Hannover Medical School, Hanover, Germany"
    ],
    "start_date": "2018-06-26",
    "completion_date": "2020-06-18",
    "last_update": "2020-11-23",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03584750"
  },
  {
    "nct_id": "NCT04089410",
    "title": "Direct and Cross Effects of Adaptation to Systemic Hyperthermia: Impact on Quality of Life, Neurohormonal and Psychophysiological Human Status",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 67,
    "conditions": [
      "Hypoxia, Altitude",
      "Exercise Tolerance",
      "Metabolic Disturbance",
      "Quality of Life"
    ],
    "interventions": [
      {
        "name": "Hyperthermic Fitness Treatment (HFT)",
        "type": "DEVICE"
      },
      {
        "name": "Placebo Hyperthermic Fitness Treatment",
        "type": "DEVICE"
      },
      {
        "name": "Physical Examination",
        "type": "OTHER"
      },
      {
        "name": "Assessment of Cardiorespiratory Fitness",
        "type": "OTHER"
      },
      {
        "name": "Autonomic Balance, Orthostatic and Hypoxic tolerance",
        "type": "OTHER"
      },
      {
        "name": "Psychological Testing",
        "type": "OTHER"
      },
      {
        "name": "Measurement of Blood Markers",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Students health and quality of life laboratory, Moscow, Russia"
    ],
    "start_date": "2019-01-14",
    "completion_date": "2019-12-27",
    "last_update": "2020-11-16",
    "topics": [
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04089410"
  },
  {
    "nct_id": "NCT04425330",
    "title": "Effects of Physical Therapy Associated With Photobiomodulation on Myelomeningocele",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Physical Therapy Modalities"
    ],
    "interventions": [
      {
        "name": "physiotherapy exercises",
        "type": "OTHER"
      },
      {
        "name": "PBM",
        "type": "OTHER"
      },
      {
        "name": "SHAM PBM",
        "type": "OTHER"
      }
    ],
    "locations": [],
    "start_date": "2020-11-03",
    "completion_date": "2022-02-03",
    "last_update": "2020-10-06",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04425330"
  },
  {
    "nct_id": "NCT04155268",
    "title": "Flotation-REST for Chronic Pain, Stress, and Sleep",
    "status": "WITHDRAWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 0,
    "conditions": [
      "Healthy",
      "Chronic Pain",
      "Musculoskeletal Pain"
    ],
    "interventions": [
      {
        "name": "Flotation-REST",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Dark Room",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [],
    "start_date": "2020-03-09",
    "completion_date": "2020-09-08",
    "last_update": "2020-09-08",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04155268"
  },
  {
    "nct_id": "NCT04025619",
    "title": "Development of Novel Adhesive Sports Tape Modular to Facilitate Use of Discomfort",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 86,
    "conditions": [
      "Cardiovascular Disease"
    ],
    "interventions": [
      {
        "name": "tape",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "National Defense of Medical Center, Tri-Service General Hospital, Taipei, Taiwan"
    ],
    "start_date": "2018-03-12",
    "completion_date": "2019-06-20",
    "last_update": "2020-09-08",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04025619"
  },
  {
    "nct_id": "NCT03359265",
    "title": "Evaluate the Clinical Efficacy of Precious Metal Fiber Textile (Germanium Titanium π Element) for Erectile Dysfunction",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Erectile Dysfunction"
    ],
    "interventions": [
      {
        "name": "underpants",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "National Defense of Medical Center, Tri-Service General Hospital, Taipei, Taiwan"
    ],
    "start_date": "2015-11-25",
    "completion_date": "2016-12-31",
    "last_update": "2020-09-08",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03359265"
  },
  {
    "nct_id": "NCT02077647",
    "title": "Focused Registry on the Conservative Treatment of Osteoarthritis of the Knee",
    "status": "COMPLETED",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 20,
    "conditions": [
      "Osteoarthritis, Knee",
      "Osteonecrosis"
    ],
    "interventions": [],
    "locations": [
      "Nagasaki University, Nagasaki, Japan",
      "Osaka Koseinenkin Hospital, Osaka, Japan",
      "Hashiba Orthopaedic Clinic, Toyama, Japan",
      "Toyama Municipal Hospital, Toyama, Japan"
    ],
    "start_date": "2014-03",
    "completion_date": "2019-07",
    "last_update": "2020-08-11",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02077647"
  },
  {
    "nct_id": "NCT04273789",
    "title": "Effect of Far Infrared Reflecting Sleepwear on Recovery and Sleep",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 18,
    "conditions": [
      "Exercise Induced Muscle Damage"
    ],
    "interventions": [
      {
        "name": "Far infrared reflecting sleepwear",
        "type": "DEVICE"
      },
      {
        "name": "Placebo sleepwear",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "SMS lab, Zurich, Switzerland"
    ],
    "start_date": "2020-02-17",
    "completion_date": "2020-07-02",
    "last_update": "2020-07-31",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04273789"
  },
  {
    "nct_id": "NCT04299568",
    "title": "Effects of Anti-gravity Treadmill Training on Knee Osteoarthritis in Geriatric Population.",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 50,
    "conditions": [
      "Osteo Arthritis Knee"
    ],
    "interventions": [
      {
        "name": "Anti gravity treadmill training",
        "type": "DEVICE"
      },
      {
        "name": "Physical Therapy",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Foundation University Institute of Rehabilitation Sciences., Islamabad, Federal, Pakistan"
    ],
    "start_date": "2020-02-28",
    "completion_date": "2020-03-30",
    "last_update": "2020-07-27",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04299568"
  },
  {
    "nct_id": "NCT04481984",
    "title": "Effectiveness of a Home-based, Self-administered Exercise Program for Hands in Patients With Systemic Sclerosis",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 50,
    "conditions": [
      "Systemic Sclerosis",
      "Scleroderma",
      "Hand Rheumatism",
      "Rehabilitation"
    ],
    "interventions": [
      {
        "name": "Home-based Hand exercise",
        "type": "OTHER"
      },
      {
        "name": "Care advice",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Cukurova University, Adana, Saricam, Turkey (Türkiye)"
    ],
    "start_date": "2016-07-15",
    "completion_date": "2019-06-05",
    "last_update": "2020-07-19",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04481984"
  },
  {
    "nct_id": "NCT04349085",
    "title": "Effects of Photobiomodulation Therapy Combined With Static Magnetic Field in CrossFit® Athletes",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 12,
    "conditions": [
      "Muscle Strength"
    ],
    "interventions": [
      {
        "name": "Effective PBMT/sMF",
        "type": "DEVICE"
      },
      {
        "name": "Placebo PBMT/sMF",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Laboratory of Phototherapy and Innovative Technologies in Health, São Paulo, Brazil"
    ],
    "start_date": "2020-04-17",
    "completion_date": "2020-05-10",
    "last_update": "2020-07-09",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04349085"
  },
  {
    "nct_id": "NCT03898089",
    "title": "The Effects of Myofascial Release Technique",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 36,
    "conditions": [
      "Low Back Pain",
      "Exercise",
      "Elderly"
    ],
    "interventions": [
      {
        "name": "Core Stability Exercise",
        "type": "OTHER"
      },
      {
        "name": "Core Stability Exercise plus Myofascial Release Technique Group",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Kırşehir Ahi Evran University School of Physical Therapy and Rehabilitation, Kırşehir, Turkey (Türkiye)"
    ],
    "start_date": "2019-03-01",
    "completion_date": "2019-08-15",
    "last_update": "2020-07-03",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03898089"
  },
  {
    "nct_id": "NCT04290637",
    "title": "The Galway Sea Swimmers Study",
    "status": "SUSPENDED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 150,
    "conditions": [
      "Cardiovascular Diseases",
      "Hypertension"
    ],
    "interventions": [
      {
        "name": "Cold-water sea swimming",
        "type": "OTHER"
      },
      {
        "name": "No cold-water sea swimming",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Croi Heart and Stroke Centre, Galway, Ireland"
    ],
    "start_date": "2020-10",
    "completion_date": "2021-10",
    "last_update": "2020-06-26",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04290637"
  },
  {
    "nct_id": "NCT02370004",
    "title": "Flexibility and Strength Training in Asthma",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 11,
    "conditions": [
      "Asthma"
    ],
    "interventions": [
      {
        "name": "Resistive Flexibility and Strength Training",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Brigham and Women's Hospital, Boston, Massachusetts, United States"
    ],
    "start_date": "2014-07",
    "completion_date": "2015-04",
    "last_update": "2020-05-28",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02370004"
  },
  {
    "nct_id": "NCT03375229",
    "title": "Dry Needling and Low-level Laser Therapy to Treat Myofascial Pain",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 43,
    "conditions": [
      "Myofascial Pain",
      "Trigger Points"
    ],
    "interventions": [
      {
        "name": "Dry Needling",
        "type": "OTHER"
      },
      {
        "name": "Low-Level Laser Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Universidade Federal de Santa Catarina, Araranguá, Santa Catarina, Brazil"
    ],
    "start_date": "2018-04-01",
    "completion_date": "2019-07-31",
    "last_update": "2020-05-21",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03375229"
  },
  {
    "nct_id": "NCT04392752",
    "title": "Fitness Study 2020",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Weight Reduction",
      "Diet; Deficiency"
    ],
    "interventions": [
      {
        "name": "Dieting intervention",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Jyväskylä, Jyväskylä, Finland"
    ],
    "start_date": "2019-02-02",
    "completion_date": "2020-08-01",
    "last_update": "2020-05-12",
    "topics": [
      "exercise-recovery",
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Exercise Recovery",
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04392752"
  },
  {
    "nct_id": "NCT03420391",
    "title": "PBMT on Muscular Performance and Recovery in Different Time-points",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Phototherapy"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation Therapy (PBMT)",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Universidade Nove de Julho, São Paulo, Brazil"
    ],
    "start_date": "2019-05-20",
    "completion_date": "2019-07-19",
    "last_update": "2020-04-27",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03420391"
  },
  {
    "nct_id": "NCT04344067",
    "title": "Far Infrared Therapy on Peritoneal Function of CAPD Patients",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE3"
    ],
    "enrollment": 100,
    "conditions": [
      "End-stage Renal Disease"
    ],
    "interventions": [
      {
        "name": "Far Infrared Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Taipei Veterans General Hospital, Taipei, Taiwan"
    ],
    "start_date": "2016-01-01",
    "completion_date": "2020-06-30",
    "last_update": "2020-04-20",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04344067"
  },
  {
    "nct_id": "NCT04287153",
    "title": "Cryotherapy and Body Slimming",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Obesity",
      "Cryotherapy Effect",
      "Weight Loss"
    ],
    "interventions": [
      {
        "name": "Cryotherapy on abdomen and saddlebags",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Cryoesthetic, Paris, France"
    ],
    "start_date": "2017-09-17",
    "completion_date": "2018-09-17",
    "last_update": "2020-02-25",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04287153"
  },
  {
    "nct_id": "NCT03949296",
    "title": "Mindfulness Meditation in Treating Insomnia in Multiple Sclerosis",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 49,
    "conditions": [
      "Insomnia Chronic",
      "Multiple Sclerosis"
    ],
    "interventions": [
      {
        "name": "Mindfulness Intervention",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Sleep Hygiene",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Yale-Griffin Prevention Research Center, Derby, Connecticut, United States"
    ],
    "start_date": "2017-12-11",
    "completion_date": "2019-12-16",
    "last_update": "2020-02-25",
    "topics": [
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03949296"
  },
  {
    "nct_id": "NCT04276038",
    "title": "Evaluation of the Efficacy of a Home-Use Photobiomodulation Device for the Treatment of Patients With Knee Osteoarthritis: A Prospective Double Blind, Randomized, Sham-Controlled Clinical Study",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 52,
    "conditions": [
      "Knee Osteoarthritis"
    ],
    "interventions": [
      {
        "name": "B-Cure laser pro",
        "type": "DEVICE"
      }
    ],
    "locations": [],
    "start_date": "2020-03-01",
    "completion_date": "2022-03-01",
    "last_update": "2020-02-20",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04276038"
  },
  {
    "nct_id": "NCT04244071",
    "title": "The Effect of Heating on Thermal Comfort and Anxiety",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 110,
    "conditions": [
      "Anxiety",
      "Nurse-Patient Relations"
    ],
    "interventions": [
      {
        "name": "Bair Paws Blanket 81003 and FOC device 87500",
        "type": "DEVICE"
      },
      {
        "name": "routine hospital care",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Selcuk Universty, Konya, Turkey (Türkiye)"
    ],
    "start_date": "2018-03-30",
    "completion_date": "2019-05-30",
    "last_update": "2020-01-27",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04244071"
  },
  {
    "nct_id": "NCT03431636",
    "title": "Effect of Different Techniques of Recovery in Para-athletes",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 21,
    "conditions": [
      "Pain",
      "Recruitment"
    ],
    "interventions": [
      {
        "name": "immersion",
        "type": "OTHER"
      },
      {
        "name": "ice pack",
        "type": "OTHER"
      },
      {
        "name": "rest",
        "type": "OTHER"
      }
    ],
    "locations": [],
    "start_date": "2020-07-25",
    "completion_date": "2020-12-20",
    "last_update": "2020-01-23",
    "topics": [
      "cold-water-immersion",
      "exercise-recovery"
    ],
    "topic_names": [
      "Cold-Water Immersion",
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03431636"
  },
  {
    "nct_id": "NCT02451215",
    "title": "Laser Interstitial Thermal Therapy (LITT) for the Treatment of Pediatric Central Nervous System Tumors",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 10,
    "conditions": [
      "Brain Tumor"
    ],
    "interventions": [
      {
        "name": "Laser Interstitial Thermotherapy (LITT)",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Children's Hospitals and Clinics of Minnesota, Minneapolis, Minnesota, United States"
    ],
    "start_date": "2015-04",
    "completion_date": "2020-01-01",
    "last_update": "2020-01-21",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02451215"
  },
  {
    "nct_id": "NCT03118271",
    "title": "Comparison of the Effect of Lumbar Traction, Spinal Manipulation, and Surgery in the Treatment of Lumbar Disc Herniation",
    "status": "TERMINATED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Lumbar Disc Herniation",
      "Lumbar Traction",
      "Spinal Manipulation",
      "Lumbar Surgery"
    ],
    "interventions": [
      {
        "name": "lumbar traction",
        "type": "DEVICE"
      },
      {
        "name": "spinal manipulation",
        "type": "PROCEDURE"
      },
      {
        "name": "surgery",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "ShinKongHospital, Taipei, Taiwan"
    ],
    "start_date": "2017-01",
    "completion_date": "2019-12",
    "last_update": "2020-01-20",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03118271"
  },
  {
    "nct_id": "NCT04198532",
    "title": "Contrast Bath and Sympathetic Skin Response",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 40,
    "conditions": [
      "Stroke",
      "Sympathetic Disorder"
    ],
    "interventions": [
      {
        "name": "Contrast bath",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Istanbul Physical Medicine and Rehabilitation Training and research Hospital, Istanbul, Turkey (Türkiye)",
      "Istanbul PMR Training and Research Hospital, Istanbul, Turkey (Türkiye)"
    ],
    "start_date": "2018-01-01",
    "completion_date": "2019-03-31",
    "last_update": "2019-12-24",
    "topics": [
      "contrast-therapy"
    ],
    "topic_names": [
      "Contrast Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04198532"
  },
  {
    "nct_id": "NCT04190797",
    "title": "Photobiomodulation on Postoperative Pain",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 34,
    "conditions": [
      "Knee Osteoarthritis",
      "Metabolic Disease"
    ],
    "interventions": [
      {
        "name": "Photobiomodulation + patiente controled anaethesia (PCA)",
        "type": "DEVICE"
      },
      {
        "name": "Placebo + patiente controled anaethesia (PCA)",
        "type": "DEVICE"
      }
    ],
    "locations": [],
    "start_date": "2019-12-01",
    "completion_date": "2020-08-01",
    "last_update": "2019-12-05",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04190797"
  },
  {
    "nct_id": "NCT04183816",
    "title": "Effect of Total Cold Water Immersion Vs Ice Massage Modalities",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 60,
    "conditions": [
      "Exercise-induced Muscle Damage"
    ],
    "interventions": [
      {
        "name": "Total cold-water immersion",
        "type": "OTHER"
      },
      {
        "name": "Ice massage",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Lebanese German University, Jounieh, Keserwan, Lebanon"
    ],
    "start_date": "2018-11-01",
    "completion_date": "2019-01-20",
    "last_update": "2019-11-28",
    "topics": [
      "cold-water-immersion",
      "exercise-recovery"
    ],
    "topic_names": [
      "Cold-Water Immersion",
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04183816"
  },
  {
    "nct_id": "NCT03695458",
    "title": "Local and Systemic Effects of Photobiomodulation Therapy on Muscle Performance and Recovery Post-exercise.",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Phototherapy",
      "Low-level Laser Therapy",
      "Systemic"
    ],
    "interventions": [
      {
        "name": "Phototherapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Universidade Nove de Julho, São Paulo, São Paulo, Brazil"
    ],
    "start_date": "2019-01-14",
    "completion_date": "2019-05-14",
    "last_update": "2019-11-28",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03695458"
  },
  {
    "nct_id": "NCT04092088",
    "title": "Effects of Cerebral & Peripheral Electrical Stimulation on Pain and Function in CTS",
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      "NA"
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        "name": "tDCS-r",
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      {
        "name": "TENS-r",
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      {
        "name": "tDCS-s",
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        "name": "TENS-s",
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    ],
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    "completion_date": "2020-10",
    "last_update": "2019-09-16",
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    "url": "https://clinicaltrials.gov/study/NCT04092088"
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    "nct_id": "NCT03920436",
    "title": "Effects of Oral Ingestion of Drinking Water Using a Tumbler That Emits Far Infrared Rays on Metabolic Profile",
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    ],
    "locations": [
      "Pusan National University Yangsan Hospital, Yangsan, Gyeungsangnam-do, South Korea"
    ],
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    "last_update": "2019-09-10",
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      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03920436"
  },
  {
    "nct_id": "NCT03981120",
    "title": "The Effect of Acupuncture on Pregnancy Rates in Women Undergoing in Vitro Fertilization With Preimplantation Genetic Screening",
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      "NA"
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        "name": "Laser and Traditional Acupuncture",
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    ],
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    "last_update": "2019-09-04",
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      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03981120"
  },
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    "nct_id": "NCT04071002",
    "title": "Patients With Distal Radius Fracture",
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        "name": "12 weeks physical therapy programme",
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      }
    ],
    "locations": [
      "Pamukkale University, Denizli, Kinikli, Turkey (Türkiye)"
    ],
    "start_date": "2015-01-21",
    "completion_date": "2016-09-01",
    "last_update": "2019-08-24",
    "topics": [
      "contrast-therapy"
    ],
    "topic_names": [
      "Contrast Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT04071002"
  },
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    "nct_id": "NCT02408965",
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        "name": "Methergine",
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    ],
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    "last_update": "2019-08-15",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02408965"
  },
  {
    "nct_id": "NCT03803956",
    "title": "Infrared Low-level Laser Therapy Before Intense Progressive Running Test of High-level Soccer Players",
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      "Skeletal Muscle Recovery"
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      {
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    "locations": [
      "Laboratory of Phototherapy and Innovative Technologies in Health, São Paulo, Brazil"
    ],
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    "completion_date": "2019-02-16",
    "last_update": "2019-07-16",
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      "photobiomodulation"
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      "Photobiomodulation / Red Light"
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    "url": "https://clinicaltrials.gov/study/NCT03803956"
  },
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    "nct_id": "NCT03992508",
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      "NA"
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      {
        "name": "intermittent pneumatic compression",
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      {
        "name": "complex decongestive therapy",
        "type": "PROCEDURE"
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    ],
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    "completion_date": "2018-12-30",
    "last_update": "2019-06-19",
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      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03992508"
  },
  {
    "nct_id": "NCT01883947",
    "title": "Effects of Touch Massage in the Sub-acute Phase After Stroke",
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      "NA"
    ],
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        "name": "Touch massage",
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      {
        "name": "non-TENS",
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      }
    ],
    "locations": [
      "Norrlands university hospital, Umeå, Sweden"
    ],
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    "completion_date": "2018-06",
    "last_update": "2019-06-14",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01883947"
  },
  {
    "nct_id": "NCT02267811",
    "title": "The Effect of OrthoPulse™ on the Rate of Orthodontic Tooth Movement",
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      "NA"
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      {
        "name": "Orthodontic Treatment",
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      },
      {
        "name": "OrthoPulse™",
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      }
    ],
    "locations": [
      "Stone Oak Orthodontics, San Antonio, Texas, United States"
    ],
    "start_date": "2013-10",
    "completion_date": "2016-06",
    "last_update": "2019-05-17",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02267811"
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  {
    "nct_id": "NCT02790255",
    "title": "BRown Fat Activity Measurement With Infrared imaginG tHermography andThermogenesis - the BRIGHT Study",
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      "NA"
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      "Adipose Tissue, Brown"
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        "name": "Cold air",
        "type": "OTHER"
      },
      {
        "name": "Cold water",
        "type": "OTHER"
      }
    ],
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    "completion_date": "2018-11-05",
    "last_update": "2019-05-14",
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      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02790255"
  },
  {
    "nct_id": "NCT03695731",
    "title": "Influence of Diabetic Neuropathy on Activation of Brown Adipose Tissue",
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      "NA"
    ],
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      "Diabetes Mellitus, Type 1"
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      {
        "name": "cold induced activation of brown adipose tissue",
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    ],
    "locations": [
      "Geneva University Hospital, Geneva, Switzerland"
    ],
    "start_date": "2018-10-15",
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    "last_update": "2019-05-07",
    "topics": [
      "cold-water-immersion"
    ],
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      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03695731"
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    "nct_id": "NCT02409108",
    "title": "Perfusion-Induced Hyperthermia for Metastatic Carcinoma",
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    ],
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      "Solid Tumor, Adult"
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      {
        "name": "Exatherm-TBH system",
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      }
    ],
    "locations": [
      "University of Kentucky, Markey Cancer Center, Lexington, Kentucky, United States"
    ],
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    "last_update": "2019-04-10",
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      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02409108"
  },
  {
    "nct_id": "NCT03465228",
    "title": "Effects of Photobiomodulation and Deep Water Running Training in Subjects With Low Back Pain.",
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      "NA"
    ],
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      "Exertion; Excess"
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        "name": "Training and LED group",
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      {
        "name": "Training group",
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      {
        "name": "LED group",
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      }
    ],
    "locations": [
      "Rodrigo Antonio Carvalho ANDRAUS, Londrina, Paraná, Brazil"
    ],
    "start_date": "2017-11-15",
    "completion_date": "2018-12-30",
    "last_update": "2019-04-01",
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      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
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    "url": "https://clinicaltrials.gov/study/NCT03465228"
  },
  {
    "nct_id": "NCT03859505",
    "title": "Photobiomodulation Therapy on Inflammatory Mediators on Low Back Pain",
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      "NA"
    ],
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        "name": "Placebo PBMT",
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      {
        "name": "Active PBMT",
        "type": "DEVICE"
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    ],
    "locations": [
      "University of Bergen, Bergen, Norway"
    ],
    "start_date": "2019-03-18",
    "completion_date": "2019-03-29",
    "last_update": "2019-03-29",
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      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03859505"
  },
  {
    "nct_id": "NCT03240497",
    "title": "Effects of Cold Exposure and Breathing Techniques on Immune Response",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
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      "NA"
    ],
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      "Inflammation",
      "Endotoxemia"
    ],
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      {
        "name": "Cold Exposure",
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      {
        "name": "Strength Ventilation",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Radboud University Medical Centre, Intensive Care, Nijmegen, Netherlands"
    ],
    "start_date": "2016-04-12",
    "completion_date": "2018-04",
    "last_update": "2019-03-29",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
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    "url": "https://clinicaltrials.gov/study/NCT03240497"
  },
  {
    "nct_id": "NCT03080207",
    "title": "Platelet Rich Plasma, Complex Decongestive Physiotherapy and Low Level Laser in Treatment of Lower Extremity Lymphoedema",
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      "NA"
    ],
    "enrollment": 45,
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        "name": "PRP method",
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      {
        "name": "Low Level Laser",
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      {
        "name": "Complex Decongestive Physiotherapy",
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    ],
    "locations": [
      "Istanbul University Faculty of Health Science, Istanbul, Turkey (Türkiye)"
    ],
    "start_date": "2017-01-17",
    "completion_date": "2018-01-01",
    "last_update": "2019-03-15",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03080207"
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  {
    "nct_id": "NCT03864770",
    "title": "Extracorporeal Shock Wave Therapy Treatment for Nocturnal Leg Cramps",
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      "NA"
    ],
    "enrollment": 30,
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      "Nocturnal Leg Cramps"
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      {
        "name": "Extracorporeal shock wave therapy",
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      },
      {
        "name": "General physical therapy",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "China Medical University Hospital, Taichung, Taiwan"
    ],
    "start_date": "2019-03-05",
    "completion_date": "2020-02-04",
    "last_update": "2019-03-07",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03864770"
  },
  {
    "nct_id": "NCT03229330",
    "title": "Low-level Light Therapy on Treatment of Venous Ulcers Assesed by Nursing Outcome Classification (NOC)",
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      "NA"
    ],
    "enrollment": 40,
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      "Venous Ulcer",
      "Low-Level Light Therapy"
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      {
        "name": "Low-level Light Therapy",
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      {
        "name": "Conventional treatment",
        "type": "COMBINATION_PRODUCT"
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    ],
    "locations": [
      "Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil"
    ],
    "start_date": "2016-04",
    "completion_date": "2018-12",
    "last_update": "2019-02-25",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03229330"
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  {
    "nct_id": "NCT02000908",
    "title": "Photobiomodulation Therapy Using the Realief Therapy System for the Treatment of Chemotherapy-associated Peripheral Neuropathy",
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    "study_type": "INTERVENTIONAL",
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      "NA"
    ],
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      "Chemotherapy-induced Peripheral Neuropathy"
    ],
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      {
        "name": "photobiomodulation",
        "type": "DEVICE"
      },
      {
        "name": "Sham treatment",
        "type": "OTHER"
      },
      {
        "name": "Physiotherapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Minnesota Gynecologic Cancer Center, Minneapolis, Minnesota, United States"
    ],
    "start_date": "2014-01",
    "completion_date": "2017-01-06",
    "last_update": "2019-02-07",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02000908"
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  {
    "nct_id": "NCT03359824",
    "title": "Brown Adipose Tissue Activation: Effect of Exercise Training and Irisin",
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      "NA"
    ],
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      "Physical Activity"
    ],
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      {
        "name": "Exercise",
        "type": "OTHER"
      }
    ],
    "locations": [],
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    "completion_date": "2015-05-27",
    "last_update": "2019-01-18",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03359824"
  },
  {
    "nct_id": "NCT03782714",
    "title": "Low-level Laser Therapy Versus Formocresol in Primary Molar Pulpotomies",
    "status": "COMPLETED",
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      "NA"
    ],
    "enrollment": 36,
    "conditions": [
      "Pulpotomy"
    ],
    "interventions": [
      {
        "name": "Low-level laser therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "King Abdulaziz University, Dental University Hospital, Jeddah, Saudi Arabia"
    ],
    "start_date": "2017-02-01",
    "completion_date": "2018-02-01",
    "last_update": "2018-12-18",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03782714"
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  {
    "nct_id": "NCT00004136",
    "title": "Heat Therapy in Treating Patients With Unresectable Primary or Metastatic Liver Cancer",
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      "PHASE2"
    ],
    "enrollment": 59,
    "conditions": [
      "Liver Cancer",
      "Metastatic Cancer"
    ],
    "interventions": [
      {
        "name": "Radiofrequency Ablation",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "University of Texas - MD Anderson Cancer Center, Houston, Texas, United States"
    ],
    "start_date": "1998-03-09",
    "completion_date": "2006-01-25",
    "last_update": "2018-11-02",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00004136"
  },
  {
    "nct_id": "NCT03677674",
    "title": "The Effects of Dehydration on the Performance of Judoka",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
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      "NA"
    ],
    "enrollment": 27,
    "conditions": [
      "Dehydration"
    ],
    "interventions": [
      {
        "name": "Dehydration",
        "type": "OTHER"
      }
    ],
    "locations": [],
    "start_date": "2018-10-01",
    "completion_date": "2020-01-30",
    "last_update": "2018-09-18",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03677674"
  },
  {
    "nct_id": "NCT03673384",
    "title": "Effect of Health Promotion on Allergic Rhinitis by Infrared-C Ray Irradiation",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 50,
    "conditions": [
      "Allergic Rhinitis"
    ],
    "interventions": [
      {
        "name": "infrared-C ray irradiation",
        "type": "DEVICE"
      },
      {
        "name": "eye mask",
        "type": "DEVICE"
      },
      {
        "name": "Xyzal Oral Product",
        "type": "DRUG"
      },
      {
        "name": "Fluticasone Furoate",
        "type": "DRUG"
      }
    ],
    "locations": [],
    "start_date": "2015-03-02",
    "completion_date": "2017-07-30",
    "last_update": "2018-09-13",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03673384"
  },
  {
    "nct_id": "NCT03268564",
    "title": "Promoting HIV Self-testing With Real-time Online Counseling for MSM in Hong Kong",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 350,
    "conditions": [
      "Uptake of HIVST-online"
    ],
    "interventions": [
      {
        "name": "HIVST-online promotion",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Centre for Health Behaviours Research, the Chinese University of Hong Kong, Hong Kong, Hong Kong"
    ],
    "start_date": "2017-01-01",
    "completion_date": "2017-12-31",
    "last_update": "2018-09-05",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03268564"
  },
  {
    "nct_id": "NCT03535493",
    "title": "The Effect of ACT and Float REST on Burnout Syndrome.",
    "status": "TERMINATED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 45,
    "conditions": [
      "Burnout Syndrome"
    ],
    "interventions": [
      {
        "name": "Acceptance and Commitment Therapy (ACT)",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Float REST",
        "type": "BEHAVIORAL"
      },
      {
        "name": "ACT + Float REST",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "International Behavioral Research Institute, Saint Charles, Illinois, United States"
    ],
    "start_date": "2018-06-01",
    "completion_date": "2018-08-27",
    "last_update": "2018-08-27",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03535493"
  },
  {
    "nct_id": "NCT02267824",
    "title": "The Effects of Extraoral Photobiomodulation on the Rate of Orthodontic Alignment",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 101,
    "conditions": [
      "Malocclusion"
    ],
    "interventions": [
      {
        "name": "Extraoral OrthoPulse® PBM",
        "type": "DEVICE"
      },
      {
        "name": "Fixed Orthodontic Appliance Treatment",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Department of Orthodontics, School of Dentistry, University of Alabama, Birmingham, Alabama, United States",
      "Shaughnessy Orthodontics, Suwanee, Georgia, United States",
      "Clinique Dentaire Alvaro de la Fuente, L'Ile Perrot, Quebec, Canada",
      "Department of Orthodontics, Faculty of Dentistry, Mahidol University, Bangkok, Thailand"
    ],
    "start_date": "2010-12",
    "completion_date": "2013-03",
    "last_update": "2018-08-23",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02267824"
  },
  {
    "nct_id": "NCT03565952",
    "title": "Effects of Cranial Massage in Menopausal Women",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 50,
    "conditions": [
      "Menopausal Women"
    ],
    "interventions": [
      {
        "name": "Cranial massage",
        "type": "OTHER"
      },
      {
        "name": "Control group",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Faculty of Physiotherapy, Valencia, Spain"
    ],
    "start_date": "2018-05-30",
    "completion_date": "2018-08-15",
    "last_update": "2018-08-16",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03565952"
  },
  {
    "nct_id": "NCT02381483",
    "title": "Vitamin A in Brown Fat Activity",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 66,
    "conditions": [
      "Brown Adipose Tissue"
    ],
    "interventions": [
      {
        "name": "Cold exposure",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Medical University of Vienna, Vienna, Austria"
    ],
    "start_date": "2014-02",
    "completion_date": "2018-04-15",
    "last_update": "2018-08-16",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02381483"
  },
  {
    "nct_id": "NCT03578666",
    "title": "Massage Versus Cold Water Immersion for Fatigue-induced Biomechanical Alterations",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 48,
    "conditions": [
      "Running",
      "Fatigue"
    ],
    "interventions": [
      {
        "name": "Massage",
        "type": "OTHER"
      },
      {
        "name": "Cold water immersion",
        "type": "OTHER"
      }
    ],
    "locations": [],
    "start_date": "2016-03-01",
    "completion_date": "2016-07-01",
    "last_update": "2018-07-06",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03578666"
  },
  {
    "nct_id": "NCT02979743",
    "title": "MRI-based Neuroimaging Predictors of Clinical Improvements Following Therapy in Children With Cerebral Palsy",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 50,
    "conditions": [
      "Brain Injury, Chronic",
      "Cerebral Palsy"
    ],
    "interventions": [
      {
        "name": "Occupational therapy",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Occupational therapy puls acupuncture and massage methods",
        "type": "OTHER"
      }
    ],
    "locations": [
      "First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China"
    ],
    "start_date": "2016-12",
    "completion_date": "2019-12",
    "last_update": "2018-06-27",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02979743"
  },
  {
    "nct_id": "NCT03563898",
    "title": "Feasibility and Safety in the Management of Fluid Overload in Peritoneal Dialysis Patients Through Sweat Stimulation With the Use of Portable Sauna Bath, Pilot Study",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 10,
    "conditions": [
      "Fluid Overload",
      "Peritoneal Dialysis Complication"
    ],
    "interventions": [
      {
        "name": "Sweating with Portable Sauna Bath",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Hosptal Civil Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico"
    ],
    "start_date": "2018-05-28",
    "completion_date": "2018-06-11",
    "last_update": "2018-06-19",
    "topics": [
      "sauna-heat-therapy",
      "sleep-and-passive-heating"
    ],
    "topic_names": [
      "Sauna & Heat Therapy",
      "Sleep & Passive Heating"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03563898"
  },
  {
    "nct_id": "NCT03566186",
    "title": "Effects of Phototherapy Associated With Sprint and Squat Training on Cardiac Autonomic Modulation",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 39,
    "conditions": [
      "Phototherapy",
      "Autonomic Nervous System",
      "Training"
    ],
    "interventions": [
      {
        "name": "Phototherapy",
        "type": "OTHER"
      },
      {
        "name": "Placebo",
        "type": "OTHER"
      },
      {
        "name": "Passive recovery",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Franciele Marques Vanderlei, Presidente Prudente, São Paulo, Brazil"
    ],
    "start_date": "2017-09-03",
    "completion_date": "2017-12-19",
    "last_update": "2018-06-11",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03566186"
  },
  {
    "nct_id": "NCT01730105",
    "title": "Chronic Cold Exposure and Energy Metabolism in Humans",
    "status": "COMPLETED",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 7,
    "conditions": [
      "Healthy"
    ],
    "interventions": [],
    "locations": [
      "National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States"
    ],
    "start_date": "2012-11-17",
    "completion_date": "2018-05-10",
    "last_update": "2018-05-11",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01730105"
  },
  {
    "nct_id": "NCT02651766",
    "title": "The Effects of Cupping Massage in Patients With Chronic Neck Pain - A Randomized Controlled Trial",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 50,
    "conditions": [
      "Neck Pain",
      "Mechanical/Motor Problems With Neck and Trunk"
    ],
    "interventions": [
      {
        "name": "Cupping massage",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Knappschaftskrankenhaus, Essen, North Rhine-Westphalia, Germany"
    ],
    "start_date": "2009-05",
    "completion_date": "2011-02",
    "last_update": "2018-04-30",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02651766"
  },
  {
    "nct_id": "NCT03484897",
    "title": "Soothing and Barrier Restoration Activity of a Body Cream for Atopic Skin",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 22,
    "conditions": [
      "Atopic Dermatitis"
    ],
    "interventions": [
      {
        "name": "P927 - LICHTENA DermAD CREMA CORPO",
        "type": "OTHER"
      }
    ],
    "locations": [
      "DERMING, Milan, MI, Italy"
    ],
    "start_date": "2018-01-12",
    "completion_date": "2018-03-20",
    "last_update": "2018-03-26",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03484897"
  },
  {
    "nct_id": "NCT02891499",
    "title": "Influence of Low-level Laser Therapy on Stability and Displacement of Orthodontic Miniscrew Implants",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 29,
    "conditions": [
      "Displacement of Other Bone Devices, Implants and Grafts",
      "Mechanical Complication of Other Bone Devices, Implants and Grafts"
    ],
    "interventions": [
      {
        "name": "Low-level laser therapy",
        "type": "PROCEDURE"
      },
      {
        "name": "Mediate force application",
        "type": "PROCEDURE"
      }
    ],
    "locations": [],
    "start_date": "2016-03",
    "completion_date": "2017-08",
    "last_update": "2018-01-17",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02891499"
  },
  {
    "nct_id": "NCT03386019",
    "title": "The Efficacy of Lymphatic Massage on Lower Extremity Edema and Performance After Treadmill Exercise in Sprinter Compare to Static Stretching and Cold Water Immersion",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 14,
    "conditions": [
      "Post-exercise Lower Extremity Edema"
    ],
    "interventions": [
      {
        "name": "Lymphatic massage",
        "type": "OTHER"
      },
      {
        "name": "Static stretching",
        "type": "OTHER"
      },
      {
        "name": "Cold water immersion",
        "type": "OTHER"
      }
    ],
    "locations": [
      "School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan"
    ],
    "start_date": "2017-11-06",
    "completion_date": "2017-12-01",
    "last_update": "2017-12-20",
    "topics": [
      "cold-water-immersion",
      "exercise-recovery"
    ],
    "topic_names": [
      "Cold-Water Immersion",
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03386019"
  },
  {
    "nct_id": "NCT02806609",
    "title": "Effect of Muscle Pain in Late Cold Water Immersion, Muscular Recruitment, Postural Control Dynamic and Sleep Quality",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 28,
    "conditions": [
      "Pain",
      "Sleep"
    ],
    "interventions": [
      {
        "name": "Cold water immersion, with 10 degrees, for 10 minutes",
        "type": "OTHER"
      },
      {
        "name": "immersion in water at room temperature",
        "type": "OTHER"
      },
      {
        "name": "active recovery - running",
        "type": "OTHER"
      },
      {
        "name": "rest in the chair",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Junior Football Team, Londrina, Paraná, Brazil"
    ],
    "start_date": "2016-06-01",
    "completion_date": "2017-05-03",
    "last_update": "2017-12-18",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02806609"
  },
  {
    "nct_id": "NCT00265863",
    "title": "Mitomycin as a Hyperthermic Peritoneal Perfusion in Treating Patients With Malignant Ascites",
    "status": "TERMINATED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE2"
    ],
    "enrollment": 1,
    "conditions": [
      "Metastatic Cancer"
    ],
    "interventions": [
      {
        "name": "mitomycin C",
        "type": "DRUG"
      }
    ],
    "locations": [
      "University of Minnesota Cancer Center, Minneapolis, Minnesota, United States"
    ],
    "start_date": "2004-08",
    "completion_date": "2005-08",
    "last_update": "2017-11-27",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00265863"
  },
  {
    "nct_id": "NCT00743119",
    "title": "Comparison of the Analgesic Effects of Dronabinol and Smoked Marijuana in Daily Marijuana Smokers",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE2"
    ],
    "enrollment": 34,
    "conditions": [
      "Pain Threshold",
      "Mood"
    ],
    "interventions": [
      {
        "name": "Placebo capsules",
        "type": "DRUG"
      },
      {
        "name": "Inactive marijuana (0% THC)",
        "type": "DRUG"
      },
      {
        "name": "Low dose Dronabinol",
        "type": "DRUG"
      },
      {
        "name": "High dose Dronabinol",
        "type": "DRUG"
      },
      {
        "name": "Low THC marijuana",
        "type": "DRUG"
      },
      {
        "name": "High THC marijuana",
        "type": "DRUG"
      }
    ],
    "locations": [
      "New York State Psychiatric Institute, New York, New York, United States"
    ],
    "start_date": "2008-06",
    "completion_date": "2013-05",
    "last_update": "2017-11-07",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00743119"
  },
  {
    "nct_id": "NCT03327168",
    "title": "Adenosine and A2A Receptors in Human Brown Adipose Tissue",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 11,
    "conditions": [
      "Obesity"
    ],
    "interventions": [
      {
        "name": "Adenosine",
        "type": "DRUG"
      },
      {
        "name": "Cold exposure",
        "type": "OTHER"
      }
    ],
    "locations": [],
    "start_date": "2015-11-01",
    "completion_date": "2016-06-30",
    "last_update": "2017-10-31",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03327168"
  },
  {
    "nct_id": "NCT02855905",
    "title": "Year-round Health Enhancing Exercise and Coronary Artery Disease",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 21,
    "conditions": [
      "Coronary Artery Disease"
    ],
    "interventions": [
      {
        "name": "Exercise/Rest and cold/neutral temperature",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Oulu, Center for Environmental and Respiratory Health Research, Oulu, Finland"
    ],
    "start_date": "2016-01",
    "completion_date": "2017-05",
    "last_update": "2017-10-31",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02855905"
  },
  {
    "nct_id": "NCT03195348",
    "title": "The Effects of Whole Body Unloading on Physiological Function",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 12,
    "conditions": [
      "Muscle Atrophy",
      "Weightlessness",
      "Sleep Disturbance",
      "Astronaut-Bone Demineralisation Syndrome"
    ],
    "interventions": [
      {
        "name": "HBF Bed Rest",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Sleep Disorders Centre, London, United Kingdom"
    ],
    "start_date": "2017-03-29",
    "completion_date": "2017-08-30",
    "last_update": "2017-10-30",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03195348"
  },
  {
    "nct_id": "NCT02075489",
    "title": "Acupressure for Pain Management and Fatigue Relief in Gulf War Veterans",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 7,
    "conditions": [
      "Persian Gulf Syndrome",
      "Chronic Fatigue Syndrome"
    ],
    "interventions": [
      {
        "name": "Acupressure treatment.",
        "type": "OTHER"
      },
      {
        "name": "Reiki",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Cleveland Clinic, Cleveland, Ohio, United States"
    ],
    "start_date": "2012-09",
    "completion_date": "2017-10",
    "last_update": "2017-10-09",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02075489"
  },
  {
    "nct_id": "NCT02832232",
    "title": "Specific Manual Approach to the Suboccipital Area on Patients With Chronic Mechanical Neck Pain",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE2"
    ],
    "enrollment": 78,
    "conditions": [
      "Neck Pain"
    ],
    "interventions": [
      {
        "name": "translational dorsal glide mobilization technique grade III",
        "type": "OTHER"
      },
      {
        "name": "pressure maintained suboccipital Inhibition technique",
        "type": "OTHER"
      },
      {
        "name": "Control Group",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Catalan Institut of Health - Sant Ildefons Rehabilitation Center, Cornellà de Llobregat, Barcelona, Spain"
    ],
    "start_date": "2016-07",
    "completion_date": "2019-10",
    "last_update": "2017-08-30",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02832232"
  },
  {
    "nct_id": "NCT02364102",
    "title": "Effect of Hypothyroidism on Brown Adipose Tissue",
    "status": "COMPLETED",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 42,
    "conditions": [
      "Hypothyroidism"
    ],
    "interventions": [],
    "locations": [
      "University Hospital Basel, Department of Endocrinology, Basel, Canton of Basel-City, Switzerland"
    ],
    "start_date": "2015-04",
    "completion_date": "2017-08",
    "last_update": "2017-08-25",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02364102"
  },
  {
    "nct_id": "NCT01598493",
    "title": "To Study the Healing Effect of Silver Impregnated Activated Carbon Fiber Wound Dressing on Deep Dermal Burn",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 30,
    "conditions": [
      "Burns"
    ],
    "interventions": [
      {
        "name": "BCT Antimicrobial Dressing",
        "type": "DEVICE"
      },
      {
        "name": "Flamazine",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Burn Center, Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan"
    ],
    "start_date": "2012-05",
    "completion_date": "2014-03",
    "last_update": "2017-07-12",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01598493"
  },
  {
    "nct_id": "NCT01598480",
    "title": "To Study the Healing Effect of Silver Impregnated Activated Carbon Fiber Wound Dressing on Superficial Dermal Burn",
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      "NA"
    ],
    "enrollment": 30,
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      "Burns"
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    "interventions": [
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        "name": "Flamazine",
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      {
        "name": "BCT Antimicrobial Dressing",
        "type": "DEVICE"
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    ],
    "locations": [
      "Burn Center, Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan"
    ],
    "start_date": "2012-05",
    "completion_date": "2014-03",
    "last_update": "2017-07-12",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01598480"
  },
  {
    "nct_id": "NCT01790581",
    "title": "Balance Training vs. Balance Training w/ STARS",
    "status": "COMPLETED",
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      "NA"
    ],
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      "Ankle (Ligaments); Instability (Old Injury)"
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        "name": "Balance Training",
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      {
        "name": "STARS",
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    ],
    "locations": [
      "University of North Carolina at Charlotte, Charlotte, North Carolina, United States"
    ],
    "start_date": "2013-01",
    "completion_date": "2014-12",
    "last_update": "2017-07-06",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01790581"
  },
  {
    "nct_id": "NCT02499809",
    "title": "The Effects of Vibration Therapy as a Recovery Tool After Intense Exercise",
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      "NA"
    ],
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      "Muscle Performance",
      "Vibration Therapy"
    ],
    "interventions": [
      {
        "name": "Recovery mode",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Wingate Institute, Netanya, Israel"
    ],
    "start_date": "2015-08",
    "completion_date": "2015-12",
    "last_update": "2017-06-12",
    "topics": [
      "cold-water-immersion",
      "exercise-recovery"
    ],
    "topic_names": [
      "Cold-Water Immersion",
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02499809"
  },
  {
    "nct_id": "NCT03160976",
    "title": "Cryolipolysis on Localized Adiposity",
    "status": "UNKNOWN",
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      "NA"
    ],
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      "Subcutaneous Fat"
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    "interventions": [
      {
        "name": "Cryolipolysis",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Federal University of Health Science of Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil"
    ],
    "start_date": "2017-05-25",
    "completion_date": "2017-10-25",
    "last_update": "2017-05-22",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03160976"
  },
  {
    "nct_id": "NCT02354807",
    "title": "Efficacy of Pharmacological Stimulation of BAT and WAT in Lean and Obese Young Adults",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
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      "PHASE2"
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      "Brown Fat"
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      {
        "name": "Mirabegron",
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      {
        "name": "Cold exposure",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Children's Hospital of Michigan, Detroit, Michigan, United States"
    ],
    "start_date": "2015-10",
    "completion_date": "2018-03",
    "last_update": "2017-05-08",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02354807"
  },
  {
    "nct_id": "NCT02240563",
    "title": "Low Level Laser Therapy for Autoimmune Thyroiditis",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
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      "NA"
    ],
    "enrollment": 43,
    "conditions": [
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        "name": "Low-level laser therapy",
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      {
        "name": "Non laser ordinary red light",
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    ],
    "locations": [
      "University of Sao Paulo General Hospital, Radiology Institute, São Paulo, Brazil",
      "University of Sao Paulo General Hospital, São Paulo, Brazil"
    ],
    "start_date": "2014-09",
    "completion_date": "2016-03",
    "last_update": "2017-05-02",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
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    "url": "https://clinicaltrials.gov/study/NCT02240563"
  },
  {
    "nct_id": "NCT03094689",
    "title": "Cold Water Immersion in the Recovery of Markers of Muscle Damage of 10km Street Runners",
    "status": "UNKNOWN",
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      "NA"
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        "name": "Cold water immersion",
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      {
        "name": "Water immersion",
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    ],
    "locations": [],
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    "completion_date": "2017-04",
    "last_update": "2017-04-27",
    "topics": [
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      "exercise-recovery"
    ],
    "topic_names": [
      "Cold-Water Immersion",
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03094689"
  },
  {
    "nct_id": "NCT01537484",
    "title": "Exploring Massage Benefits for Arthritis of the Knee",
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        "name": "Massage Therapy",
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    "locations": [
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    ],
    "start_date": "2012-06",
    "completion_date": "2015-06",
    "last_update": "2017-04-18",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
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    "url": "https://clinicaltrials.gov/study/NCT01537484"
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  {
    "nct_id": "NCT02076334",
    "title": "Effect of Compression Garments on Exercise Performance Following Acute High Intensity Exercise",
    "status": "COMPLETED",
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      "NA"
    ],
    "enrollment": 84,
    "conditions": [
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      {
        "name": "Far Infrared Fabric",
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      {
        "name": "Spandex",
        "type": "OTHER"
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    ],
    "locations": [
      "Exercise and Sport Science (University of North Carolina), Chapel Hill, North Carolina, United States"
    ],
    "start_date": "2014-02",
    "completion_date": "2014-08",
    "last_update": "2017-04-13",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
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    "url": "https://clinicaltrials.gov/study/NCT02076334"
  },
  {
    "nct_id": "NCT02034331",
    "title": "IR and Microvascular Blood Flow in SCI",
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      "Insulin Resistance"
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        "name": "Insulin iontophoresis",
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      {
        "name": "Placebo Iontophoresis",
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      {
        "name": "Acetylcholine Iontophoresis",
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      {
        "name": "Heat application",
        "type": "OTHER"
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    ],
    "locations": [
      "James J. Peters VA Medical Center, The Bronx, New York, United States"
    ],
    "start_date": "2012-12",
    "completion_date": "2016-12",
    "last_update": "2017-03-06",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
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    "url": "https://clinicaltrials.gov/study/NCT02034331"
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  {
    "nct_id": "NCT03054974",
    "title": "TCM Clinical Practice Rehabilitation of Post-stroke Spasticity",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
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      "NA"
    ],
    "enrollment": 1208,
    "conditions": [
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      {
        "name": "Modern rehabilitation treatment",
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      {
        "name": "Modern rehabilitation &TCM",
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      {
        "name": "modern rehabilitation &Baimai Ruangao",
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      {
        "name": "modern rehabilitation &Tibetan medicine",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Jiangsu Province Hospital, Nanjing, Jiangsu, China"
    ],
    "start_date": "2013-01",
    "completion_date": "2018-12",
    "last_update": "2017-02-15",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
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    "url": "https://clinicaltrials.gov/study/NCT03054974"
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  {
    "nct_id": "NCT01907139",
    "title": "Comparative Efficacy Research of Robot-Assisted Therapy With and Without Constraint-Induced Therapy in Stroke Rehabilitation",
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      "NA"
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    "enrollment": 46,
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        "name": "Robot-assisted therapy",
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        "name": "Distributed constraint-induced therapy",
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      {
        "name": "Dose-matched control therapy",
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    ],
    "locations": [
      "Buddhist Tzu Chi General Hospital Taipei Branch, New Taipei City, Taiwan, Taiwan"
    ],
    "start_date": "2013-08",
    "completion_date": "2016-07-31",
    "last_update": "2017-02-01",
    "topics": [
      "floatation-therapy"
    ],
    "topic_names": [
      "Floatation Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01907139"
  },
  {
    "nct_id": "NCT03031223",
    "title": "Evaluation of Sensory-motor Response to Low-level Laser Therapy for the Treatment of Spinal Injuries",
    "status": "UNKNOWN",
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      "NA"
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        "name": "low-level laser therapy",
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    ],
    "locations": [
      "Universidade Nove de Julho, São Paulo, São Paulo/SP, Brazil"
    ],
    "start_date": "2016-08",
    "completion_date": "2017-05",
    "last_update": "2017-01-21",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03031223"
  },
  {
    "nct_id": "NCT02725047",
    "title": "The Effect of Cryotherapy in Pain Control, Function and Quality of Life in Individuals With Knee Osteoarthritis",
    "status": "COMPLETED",
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      "NA"
    ],
    "enrollment": 60,
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      "Osteoarthritis, Knee"
    ],
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        "name": "Cryotherapy",
        "type": "OTHER"
      },
      {
        "name": "Placebo - Sand",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Federal University of São Carlos, São Carlos, São Paulo, Brazil"
    ],
    "start_date": "2016-04",
    "completion_date": "2017-01",
    "last_update": "2017-01-13",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02725047"
  },
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    "nct_id": "NCT03005691",
    "title": "Central Sensitization in Chronic Whiplash Patients",
    "status": "UNKNOWN",
    "study_type": "OBSERVATIONAL",
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      {
        "name": "Spectroscopy",
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      },
      {
        "name": "Questionnaires",
        "type": "OTHER"
      },
      {
        "name": "Conditioned Pain Modulation",
        "type": "PROCEDURE"
      }
    ],
    "locations": [],
    "start_date": "2017-01",
    "completion_date": "2017-05",
    "last_update": "2016-12-28",
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      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT03005691"
  },
  {
    "nct_id": "NCT00981370",
    "title": "Clinical Importance of Treating Iron Overload in Sickle Cell Disease",
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      "PHASE3"
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    "enrollment": 1,
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      "Anemia, Sickle Cell",
      "Transfusion Hemosiderosis"
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    "interventions": [
      {
        "name": "deferasirox",
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    "locations": [
      "Childrens Hospital Los Angeles, Los Angeles, California, United States"
    ],
    "start_date": "2009-04",
    "completion_date": "2010-12",
    "last_update": "2016-12-15",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00981370"
  },
  {
    "nct_id": "NCT02995070",
    "title": "Low Intensity Laser Therapy in Connective Tissue Graft for Root Coverage in Smokers",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
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      "NA"
    ],
    "enrollment": 30,
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        "name": "CTG",
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      {
        "name": "LLLT",
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      {
        "name": "SHAM",
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    ],
    "locations": [
      "Felipe Lucas da Silva Neves, São José dos Campos, São Paulo, Brazil"
    ],
    "start_date": "2016-09",
    "completion_date": "2017-07",
    "last_update": "2016-12-13",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02995070"
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  {
    "nct_id": "NCT01057641",
    "title": "Study on the Treatment of Degenerative Lumbar Spine Stenosis With a Percutaneous Interspinous Implant",
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    "study_type": "INTERVENTIONAL",
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      "PHASE4"
    ],
    "enrollment": 22,
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      "Lumbar Spinal Stenosis"
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    "interventions": [
      {
        "name": "Spacer",
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      },
      {
        "name": "physiotherapy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University Hospital Cologne, Cologne, North Rhine-Westphalia, Germany",
      "University Hospital of Cologne, Cologne, Germany"
    ],
    "start_date": "2011-03",
    "completion_date": "2018-06",
    "last_update": "2016-11-04",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01057641"
  },
  {
    "nct_id": "NCT02677402",
    "title": "Effects of Various Modalities Water Immersion on Veins",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 10,
    "conditions": [
      "Hydrotherapy"
    ],
    "interventions": [
      {
        "name": "immersion",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Beliard, Besançon, France"
    ],
    "start_date": "2012-12",
    "completion_date": "",
    "last_update": "2016-10-25",
    "topics": [
      "contrast-therapy"
    ],
    "topic_names": [
      "Contrast Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02677402"
  },
  {
    "nct_id": "NCT02888132",
    "title": "Echocardiography-guided Transthoracic Radio Frequency/Laser Ablation for Ventricular Septum of Hypertrophic Obstructive Cardiomyopathy",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 10,
    "conditions": [
      "Hypertrophic Obstructive Cardiomyopathy"
    ],
    "interventions": [
      {
        "name": "Echocardiography-guided transthoracic radio frequency ablation for HOCM ventricular septum",
        "type": "PROCEDURE"
      },
      {
        "name": "Echocardiography-guided transthoracic laser ablation for HOCM ventricular septum",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Ultrasound Medicine Department of Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China"
    ],
    "start_date": "2016-04",
    "completion_date": "",
    "last_update": "2016-08-29",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02888132"
  },
  {
    "nct_id": "NCT02596542",
    "title": "Cold Water Immersion and Recovery",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 12,
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      "Post-exercise Cold Water Immersion"
    ],
    "interventions": [
      {
        "name": "Water immersion",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Maastricht University, Maastricht, Limburg, Netherlands"
    ],
    "start_date": "2015-11",
    "completion_date": "2016-05",
    "last_update": "2016-08-01",
    "topics": [
      "cold-water-immersion",
      "exercise-recovery"
    ],
    "topic_names": [
      "Cold-Water Immersion",
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02596542"
  },
  {
    "nct_id": "NCT02798640",
    "title": "Comparative Study Evaluating Performance of Celliant Fibers on Tissue Oxygenation",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 153,
    "conditions": [
      "Transcutaneous Oxygen Tension"
    ],
    "interventions": [
      {
        "name": "Celliant",
        "type": "DEVICE"
      },
      {
        "name": "Control",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Hologenix, LLC, Santa Monica, California, United States"
    ],
    "start_date": "2013-09",
    "completion_date": "2014-01",
    "last_update": "2016-06-13",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02798640"
  },
  {
    "nct_id": "NCT02688972",
    "title": "The Accumulative Effect of Cold Water Immersion in Football Athletes",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 27,
    "conditions": [
      "Athletic Performance"
    ],
    "interventions": [
      {
        "name": "cold water immersion",
        "type": "OTHER"
      },
      {
        "name": "Control group",
        "type": "OTHER"
      }
    ],
    "locations": [],
    "start_date": "2015-07",
    "completion_date": "2015-08",
    "last_update": "2016-02-22",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02688972"
  },
  {
    "nct_id": "NCT01822535",
    "title": "Body Temperature in Persons With Tetraplegia When Exposed to Cold",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE4"
    ],
    "enrollment": 30,
    "conditions": [
      "Tetraplegia",
      "Hypothermia",
      "Mild Cognitive Impairment"
    ],
    "interventions": [
      {
        "name": "Midodrine hydrochloride",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Center of Excellence for the Medical Consequences of SCI, JJP VAMC, 7A-13, The Bronx, New York, United States"
    ],
    "start_date": "2011-07",
    "completion_date": "2015-10",
    "last_update": "2016-02-05",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01822535"
  },
  {
    "nct_id": "NCT02622971",
    "title": "Phototherapy and Cryotherapy in Post-exercise Skeletal Muscle Recovery",
    "status": "COMPLETED",
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      "NA"
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    "enrollment": 50,
    "conditions": [
      "Post-exercise Muscle Recovery"
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      {
        "name": "PBMT",
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      {
        "name": "Cryotherapy",
        "type": "OTHER"
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    ],
    "locations": [
      "Laboratory of Phototherapy in Sports and Exercise, Universidade Nove de Julho (UNINOVE), São Paulo, São Paulo, Brazil"
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    "completion_date": "2016-01",
    "last_update": "2016-02-02",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02622971"
  },
  {
    "nct_id": "NCT02588768",
    "title": "Photobiomodulation Therapy in a Field Test With High-level Rugby Players",
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      "NA"
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        "name": "Photobiomodulation therapy (Phototherapy)",
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    ],
    "locations": [
      "Universidade Nove de Julho, São Paulo, São Paulo, Brazil"
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    "last_update": "2016-02-02",
    "topics": [
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    "topic_names": [
      "Exercise Recovery"
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    "url": "https://clinicaltrials.gov/study/NCT02588768"
  },
  {
    "nct_id": "NCT01898949",
    "title": "Stimulation of Diet-Induced Thermogenesis by Cold-Exposure",
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      "NA"
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        "name": "Cold Exposure",
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    ],
    "locations": [
      "Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States"
    ],
    "start_date": "2010-11",
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    "last_update": "2016-01-06",
    "topics": [
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    ],
    "topic_names": [
      "Cold-Water Immersion"
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    "url": "https://clinicaltrials.gov/study/NCT01898949"
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  {
    "nct_id": "NCT02645877",
    "title": "Trends of the Pre-hospital Emergency Care Spectrum in Beijing From 2005 to 2014: A Retrospective Analysis",
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      {
        "name": "Prehospital care",
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    ],
    "locations": [
      "Beijing Emergency Center, Beijing, China, Beijing, Beijing Municipality, China",
      "Beijing Red Cross Emergency center, Beijing, Beijing Municipality, China"
    ],
    "start_date": "2005-01",
    "completion_date": "2014-12",
    "last_update": "2016-01-04",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
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    "url": "https://clinicaltrials.gov/study/NCT02645877"
  },
  {
    "nct_id": "NCT02417155",
    "title": "Increasing Plasma Adrenaline Levels Through Breathing Techniques - an Explorative Study",
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      "NA"
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    "enrollment": 40,
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        "name": "Hyper/hypoventilation",
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      {
        "name": "Strength ventilation",
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    ],
    "locations": [
      "Intensive Care Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, Gelderland, Netherlands"
    ],
    "start_date": "2014-11",
    "completion_date": "2015-10",
    "last_update": "2015-11-09",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
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    "url": "https://clinicaltrials.gov/study/NCT02417155"
  },
  {
    "nct_id": "NCT00002973",
    "title": "Melphalan and Whole-Body Hyperthermia in Treating Patients With Advanced Melanoma",
    "status": "COMPLETED",
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      "PHASE2"
    ],
    "enrollment": 34,
    "conditions": [
      "Melanoma (Skin)"
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      {
        "name": "melphalan",
        "type": "DRUG"
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      {
        "name": "hyperthermia treatment",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin, United States"
    ],
    "start_date": "1995-12",
    "completion_date": "2000-12",
    "last_update": "2015-09-30",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00002973"
  },
  {
    "nct_id": "NCT02499640",
    "title": "The Effects of Cold Water Immersion With Different Dosages (Duration and Temperature Variations) on Heart Rate Variability Post-exercise Recovery",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
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      "NA"
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    "enrollment": 100,
    "conditions": [
      "Cryotherapy Effect"
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    "interventions": [
      {
        "name": "immersion cold water",
        "type": "OTHER"
      }
    ],
    "locations": [],
    "start_date": "2014-09",
    "completion_date": "2015-05",
    "last_update": "2015-07-15",
    "topics": [
      "cold-water-immersion",
      "exercise-recovery"
    ],
    "topic_names": [
      "Cold-Water Immersion",
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02499640"
  },
  {
    "nct_id": "NCT01905098",
    "title": "Complementary and Alternative Medicine Sauna Detoxification Study: Phase I",
    "status": "TERMINATED",
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      "PHASE1"
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    "enrollment": 1,
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      "Hyperthermia"
    ],
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      {
        "name": "Sauna Detoxification Protocol",
        "type": "OTHER"
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      {
        "name": "Observation Sessions",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Bastyr University Research Institute, Clinical Research Center, Kenmore, Washington, United States"
    ],
    "start_date": "2013-07",
    "completion_date": "2014-04",
    "last_update": "2015-04-16",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01905098"
  },
  {
    "nct_id": "NCT02391376",
    "title": "Heat Transfer by Three Types of Packs and Its Implication on the Flexibility of the Lower Back",
    "status": "COMPLETED",
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      "NA"
    ],
    "enrollment": 45,
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      {
        "name": "moist heat pack; ;",
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      },
      {
        "name": "seed pack",
        "type": "OTHER"
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      {
        "name": "gel pack",
        "type": "OTHER"
      }
    ],
    "locations": [],
    "start_date": "2012-03",
    "completion_date": "2014-03",
    "last_update": "2015-03-12",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02391376"
  },
  {
    "nct_id": "NCT02365129",
    "title": "Activating Brown Adipose Tissue Through Exercise",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
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      "Diabetes Mellitus",
      "Metabolic Syndrome X"
    ],
    "interventions": [
      {
        "name": "Exercise training based on recommendations for adults (WHO)",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Granada, Granada, Granada, Spain"
    ],
    "start_date": "2015-02",
    "completion_date": "2017-07",
    "last_update": "2015-02-10",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
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    "url": "https://clinicaltrials.gov/study/NCT02365129"
  },
  {
    "nct_id": "NCT02341612",
    "title": "Cold Therapy in the Treatment of Exercise-induced Muscle Damage",
    "status": "COMPLETED",
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      "NA"
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    "enrollment": 65,
    "conditions": [
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    ],
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      {
        "name": "single exposure at 5°C in CWI",
        "type": "OTHER"
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      {
        "name": "single exposure at 15°C in CWI",
        "type": "OTHER"
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      {
        "name": "multiple exposures at 10°C in CWI",
        "type": "OTHER"
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      {
        "name": "whole body cryotherapy (WBC)",
        "type": "OTHER"
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      {
        "name": "passive recovery",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Brasília, Brasília, Federal District, Brazil"
    ],
    "start_date": "2013-12",
    "completion_date": "2014-08",
    "last_update": "2015-01-16",
    "topics": [
      "cold-water-immersion",
      "exercise-recovery"
    ],
    "topic_names": [
      "Cold-Water Immersion",
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02341612"
  },
  {
    "nct_id": "NCT01844271",
    "title": "Low Level Laser Therapy in Muscle Fatigue and Muscle Recovery",
    "status": "COMPLETED",
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    "phases": [
      "NA"
    ],
    "enrollment": 28,
    "conditions": [
      "Muscle; Fatigue, Heart",
      "Skeletal Muscle Recovery"
    ],
    "interventions": [
      {
        "name": "Low Level Laser (LLL)",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Nove de Julho University, São Paulo, São Paulo, Brazil"
    ],
    "start_date": "2013-05",
    "completion_date": "2013-12",
    "last_update": "2014-12-04",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01844271"
  },
  {
    "nct_id": "NCT01932073",
    "title": "Laser Therapy for the Management of Radiation Dermatitis",
    "status": "COMPLETED",
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      "NA"
    ],
    "enrollment": 79,
    "conditions": [
      "Radiation Dermatitis"
    ],
    "interventions": [
      {
        "name": "Low-Level Laser Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Jessa Hospital - Oncology department, Hasselt, Belgium"
    ],
    "start_date": "2013-08",
    "completion_date": "2014-07",
    "last_update": "2014-12-03",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01932073"
  },
  {
    "nct_id": "NCT02289170",
    "title": "Clinical Study to Evaluate the Safety and Efficacy of Heating and Cooling Combination Therapeutic Device(OCH-S100)",
    "status": "UNKNOWN",
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    "phases": [
      "NA"
    ],
    "enrollment": 80,
    "conditions": [
      "Chronic Low Back Pain"
    ],
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      {
        "name": "Heating and cooling combination therapy",
        "type": "DEVICE"
      },
      {
        "name": "Sham heating and cooling therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Donnguk University Oriental Medical Hospital, Seongnam-si, Gyeonggi-do, South Korea"
    ],
    "start_date": "2014-09",
    "completion_date": "2015-09",
    "last_update": "2014-11-09",
    "topics": [
      "contrast-therapy"
    ],
    "topic_names": [
      "Contrast Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02289170"
  },
  {
    "nct_id": "NCT00281359",
    "title": "A Comparative Study of the Effectiveness of Treatment of Contractures With Mechanically Applied Stretch and Heat.",
    "status": "COMPLETED",
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      "NA"
    ],
    "enrollment": 20,
    "conditions": [
      "Cerebral Palsy"
    ],
    "interventions": [
      {
        "name": "With heat",
        "type": "DEVICE"
      },
      {
        "name": "No heat",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Robert Jones and Agnes Hunt Orthopaedic and District Hospital NHS Trust, Oswestry, Shropshire, United Kingdom"
    ],
    "start_date": "2003-04",
    "completion_date": "2006-09",
    "last_update": "2014-11-04",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00281359"
  },
  {
    "nct_id": "NCT02282774",
    "title": "Subtenon Block Combined With General Anesthesia for Vitreoretinal Surgery",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE3"
    ],
    "enrollment": 80,
    "conditions": [
      "Subtenon Anesthesia"
    ],
    "interventions": [
      {
        "name": "2% lidocaine and 0.5% bupivacaine",
        "type": "DRUG"
      },
      {
        "name": "Sham subtenon block",
        "type": "DRUG"
      }
    ],
    "locations": [
      "King Abdulaziz University Hospital at King Saud University, Riyadh, Riyadh Region, Saudi Arabia"
    ],
    "start_date": "2013-12",
    "completion_date": "",
    "last_update": "2014-11-03",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT02282774"
  },
  {
    "nct_id": "NCT00760123",
    "title": "Lymphedema Prevention in Breast Cancer",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 120,
    "conditions": [
      "BREAST CANCER",
      "LYMPHEDEMA"
    ],
    "interventions": [
      {
        "name": "Early Physical Therapy and Educational strategy",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Alcalá University, Alcalá de Henares, Madrid, Spain",
      "María Torres Lacomba, Alcalá de Henares, Madrid, Spain"
    ],
    "start_date": "2005-05",
    "completion_date": "2009-12",
    "last_update": "2014-08-22",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00760123"
  },
  {
    "nct_id": "NCT01462591",
    "title": "L-citrulline Supplementation & Cold Exposure",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1",
      "PHASE2"
    ],
    "enrollment": 16,
    "conditions": [
      "Hypertension"
    ],
    "interventions": [
      {
        "name": "L-citrulline",
        "type": "DIETARY_SUPPLEMENT"
      }
    ],
    "locations": [
      "FSU College of Human Sciences, Tallahassee, Florida, United States"
    ],
    "start_date": "2011-05",
    "completion_date": "2012-05",
    "last_update": "2014-08-04",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01462591"
  },
  {
    "nct_id": "NCT01343147",
    "title": "Deep Versus Superficial Heating in Patients With Knee Osteoarthritis",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 54,
    "conditions": [
      "Knee Osteoarthritis"
    ],
    "interventions": [
      {
        "name": "Microwave diathermy",
        "type": "OTHER"
      },
      {
        "name": "Superficial hyperthermia",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Outpatient clinic of the Dept. Of Gerontology, Geriatrics and Physiatrics, Rome, Italy"
    ],
    "start_date": "2010-05",
    "completion_date": "2010-07",
    "last_update": "2014-03-04",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01343147"
  },
  {
    "nct_id": "NCT00175344",
    "title": "Does Scar Massage Improve Postoperative Pain and Function in Women With Breast Cancer?",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE3"
    ],
    "enrollment": 96,
    "conditions": [
      "Breast Cancer"
    ],
    "interventions": [
      {
        "name": "Scar massage.",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "BC Cancer Agency - Vancouver Island, Victoria, British Columbia, Canada"
    ],
    "start_date": "2004-02",
    "completion_date": "2006-04",
    "last_update": "2014-02-18",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00175344"
  },
  {
    "nct_id": "NCT01936558",
    "title": "The Origin of Phantom Limb Sensation and Phantom Limb Pain in Amputees",
    "status": "UNKNOWN",
    "study_type": "OBSERVATIONAL",
    "phases": [],
    "enrollment": 20,
    "conditions": [
      "Exposure to Infrared Radiation"
    ],
    "interventions": [
      {
        "name": "Far infrared ray to the sole",
        "type": "OTHER"
      }
    ],
    "locations": [
      "NTUH department of orthopedics; NTU department of electrical engneering, Taipei, Taiwan, Taiwan"
    ],
    "start_date": "2013-01",
    "completion_date": "2014-12",
    "last_update": "2014-01-14",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01936558"
  },
  {
    "nct_id": "NCT00036985",
    "title": "Combination Chemotherapy With or Without Microwave Thermotherapy Before Surgery in Treating Women With Locally Advanced Breast Cancer",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE2"
    ],
    "enrollment": "",
    "conditions": [
      "Breast Cancer"
    ],
    "interventions": [
      {
        "name": "cyclophosphamide",
        "type": "DRUG"
      },
      {
        "name": "doxorubicin hydrochloride",
        "type": "DRUG"
      },
      {
        "name": "conventional surgery",
        "type": "PROCEDURE"
      },
      {
        "name": "neoadjuvant therapy",
        "type": "PROCEDURE"
      },
      {
        "name": "thermal ablation therapy",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States",
      "St. Joseph Hospital Regional Cancer Center - Orange, Orange, California, United States",
      "Comprehensive Breast Center of Coral Springs, Coral Springs, Florida, United States",
      "Oklahoma University Medical Center at University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States",
      "Mroz-Baier Breast Care Center, Memphis, Tennessee, United States",
      "Breast Care Specialists, P.C., Norfolk, Virginia, United States",
      "Tacoma, Washington, United States"
    ],
    "start_date": "2001-08",
    "completion_date": "",
    "last_update": "2013-12-18",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00036985"
  },
  {
    "nct_id": "NCT01972100",
    "title": "Use of Low-level Laser Therapy (808nm) to Muscle Fatigue Resistance",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 7,
    "conditions": [
      "Healthy"
    ],
    "interventions": [
      {
        "name": "Low-level laser therapy (808nm)",
        "type": "DEVICE"
      },
      {
        "name": "isokinetic exercise",
        "type": "OTHER"
      },
      {
        "name": "Placebo low-level laser therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Federal Univesity of Rio Grande do Norte, Rio Grande Do Norte, Natal, Brazil"
    ],
    "start_date": "2013-04",
    "completion_date": "2013-10",
    "last_update": "2013-10-29",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01972100"
  },
  {
    "nct_id": "NCT00003052",
    "title": "Combination Chemotherapy With or Without Hyperthermia Therapy in Treating Patients With Soft Tissue Sarcoma",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE3"
    ],
    "enrollment": 340,
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      "Sarcoma"
    ],
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      {
        "name": "doxorubicin hydrochloride",
        "type": "DRUG"
      },
      {
        "name": "etoposide",
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      {
        "name": "ifosfamide",
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      {
        "name": "conventional surgery",
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      {
        "name": "hyperthermia treatment",
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      {
        "name": "radiation therapy",
        "type": "RADIATION"
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    ],
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      "Robert Roessle Comprehensive Cancer Center at University of Berlin - Charite Campus Buch, Berlin, Germany",
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      "Klinikum der Universitaet Muenchen - Grosshadern Campus, Munich, Germany"
    ],
    "start_date": "1997-07",
    "completion_date": "2010-06",
    "last_update": "2013-09-16",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00003052"
  },
  {
    "nct_id": "NCT01921725",
    "title": "The Clinical Application and Efficacy Verification of an Innovative Carbon Fiber Dressing",
    "status": "COMPLETED",
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      "NA"
    ],
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      "Wounds"
    ],
    "interventions": [
      {
        "name": "hydrophilic-based dressing (KoCarbonTM)",
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    ],
    "locations": [
      "Division of Plastic Surgery, Department of Surgery, China Medical University Hospital, Taichung, Taiwan",
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    ],
    "start_date": "2013-05",
    "completion_date": "",
    "last_update": "2013-08-09",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01921725"
  },
  {
    "nct_id": "NCT01793779",
    "title": "Comparison of Pre-exercise Beta-hydroxy-beta-methylbutyrate Free Acid (HMB-FA) and Cold Water Therapy for the Attenuation of Muscle Damage and Soreness",
    "status": "COMPLETED",
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      "NA"
    ],
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      },
      {
        "name": "beta-hydroxy-beta-methylbutyrate free acid (HMB-FA)",
        "type": "DIETARY_SUPPLEMENT"
      },
      {
        "name": "Placebo",
        "type": "DIETARY_SUPPLEMENT"
      }
    ],
    "locations": [
      "University of Central Florida, Sport and Exercise Science, Orlando, Florida, United States"
    ],
    "start_date": "2012-12",
    "completion_date": "2013-04",
    "last_update": "2013-07-31",
    "topics": [
      "exercise-recovery"
    ],
    "topic_names": [
      "Exercise Recovery"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01793779"
  },
  {
    "nct_id": "NCT01709058",
    "title": "Study on the Effects of Oxygen-ozone Therapy on Back Pain in Subjects Aged 65 or Older",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
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      "PHASE4"
    ],
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      {
        "name": "Intramuscular/paravertebral injections of Oxygen-Ozone",
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      },
      {
        "name": "Simulated intramuscular/paravertebral injections",
        "type": "OTHER"
      }
    ],
    "locations": [
      "INRCA Hospital, via della Montagnola, 81, Ancona, Italy"
    ],
    "start_date": "2012-08",
    "completion_date": "2015-08",
    "last_update": "2012-10-17",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01709058"
  },
  {
    "nct_id": "NCT00650260",
    "title": "Intraoperative Warming Comparison of Devices",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 42,
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    ],
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      {
        "name": "Dynatherm Medical vitalHEAT Temperature Management System vH2",
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      },
      {
        "name": "Bair Hugger™ (Arizant Healthcare, Eden Prairie, MN)",
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      }
    ],
    "locations": [
      "Tampa General Hospital, Tampa, Florida, United States"
    ],
    "start_date": "2009-02",
    "completion_date": "2009-08",
    "last_update": "2012-09-25",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00650260"
  },
  {
    "nct_id": "NCT01339715",
    "title": "The Difference Between Acupuncture and Far-infrared Ray Illumination at CV12 Acupoint",
    "status": "COMPLETED",
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    "phases": [
      "NA"
    ],
    "enrollment": 25,
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      "Reaction of Autonomic Nervous System",
      "Reaction of Acupuncture",
      "Reaction of Far Infrared Ray"
    ],
    "interventions": [
      {
        "name": "acupuncture and far-infrared ray",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "China Medical University Hospital, Taichung, Taiwan"
    ],
    "start_date": "2011-04",
    "completion_date": "2012-03",
    "last_update": "2012-07-20",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01339715"
  },
  {
    "nct_id": "NCT00832130",
    "title": "Treatment of Meibomian Gland Dysfunction and Evaporative Dry Eye",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 139,
    "conditions": [
      "Chalazion",
      "Dry Eye Syndromes"
    ],
    "interventions": [
      {
        "name": "Manual Mini System",
        "type": "DEVICE"
      },
      {
        "name": "iHeat Portable Warm Compress Therapy",
        "type": "DEVICE"
      }
    ],
    "locations": [
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      "Morrow, Georgia, United States",
      "Highland Park, Illinois, United States",
      "Edgewood, Kentucky, United States",
      "Lexington, Kentucky, United States",
      "Winchester, Massachusetts, United States",
      "Jackson, Michigan, United States",
      "Bloomington, Minnesota, United States"
    ],
    "start_date": "2009-02",
    "completion_date": "2009-08",
    "last_update": "2011-12-05",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00832130"
  },
  {
    "nct_id": "NCT01138254",
    "title": "Far Infrared Therapy on AV Fistula Flow, Endothelial Function and Echocardiography in ESRD Patients",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
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      "PHASE4"
    ],
    "enrollment": 200,
    "conditions": [
      "End Stage Renal Disease"
    ],
    "interventions": [
      {
        "name": "WSTM TY101 FIR emitter (Far infrared therapy)",
        "type": "DEVICE"
      },
      {
        "name": "no intervention",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Taipei Veterans General Hospital, Taipei, Taiwan, Taiwan"
    ],
    "start_date": "2008-11",
    "completion_date": "2011-08",
    "last_update": "2011-07-12",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01138254"
  },
  {
    "nct_id": "NCT00348777",
    "title": "THERMARTHROSE: Gonarthrosis and Water Cure",
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      "PHASE3"
    ],
    "enrollment": 462,
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      "Osteoarthritis, Knee",
      "Pain"
    ],
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      {
        "name": "thermal cure",
        "type": "DRUG"
      },
      {
        "name": "3 days access to watering place at 6 months",
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      }
    ],
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      "Cabinet Médical, Chambéry, France",
      "Hôpital thermal, Dax, France"
    ],
    "start_date": "2006-06",
    "completion_date": "2008-01",
    "last_update": "2011-06-21",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00348777"
  },
  {
    "nct_id": "NCT01339728",
    "title": "Far-infrared Ray Effect on CV12 Acupoint",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 22,
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      "Reaction of Far Infrared Ray",
      "Reaction of Skin Temperature"
    ],
    "interventions": [
      {
        "name": "far-infrared ray",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "China Medical University Hospital, Taichung, Taiwan"
    ],
    "start_date": "2010-10",
    "completion_date": "2011-04",
    "last_update": "2011-04-20",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01339728"
  },
  {
    "nct_id": "NCT00880828",
    "title": "Comparing Two Different Cervical Collars for the Treatment in Patient With Cervical Radiculopathy and Radicular Pain",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 72,
    "conditions": [
      "Cervical Radiculopathy",
      "Radicular Pain",
      "Acute Neck Pain",
      "Cervicobrachial Pain"
    ],
    "interventions": [
      {
        "name": "FIR cervical collar with Acetaminophen",
        "type": "OTHER"
      },
      {
        "name": "Conservative cervical collar with Acetaminophen",
        "type": "OTHER"
      },
      {
        "name": "Acetaminophen only",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Taipei Medical University-Wan Fang Hospital, Taipei, Taiwan"
    ],
    "start_date": "2010-08",
    "completion_date": "2011-10",
    "last_update": "2010-09-23",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00880828"
  },
  {
    "nct_id": "NCT01172574",
    "title": "Motor Control Exercise in Osteoporotic Women",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 20,
    "conditions": [
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      "Postmenopausal"
    ],
    "interventions": [
      {
        "name": "Motor control exercise",
        "type": "OTHER"
      }
    ],
    "locations": [
      "Hospital Thias Pronoias 'I Pammakaristos', Athens, Attica, Greece"
    ],
    "start_date": "2006-11",
    "completion_date": "2008-01",
    "last_update": "2010-07-29",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01172574"
  },
  {
    "nct_id": "NCT00221728",
    "title": "Comparison Between Surgery and Radiofrequency for Treatment of Renal Tumors",
    "status": "TERMINATED",
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      "PHASE2",
      "PHASE3"
    ],
    "enrollment": 160,
    "conditions": [
      "Kidney Neoplasms"
    ],
    "interventions": [
      {
        "name": "Radiofrequency",
        "type": "DEVICE"
      },
      {
        "name": "conservative surgery",
        "type": "PROCEDURE"
      }
    ],
    "locations": [
      "Service de radiologie B, Hôpital Pellegrin, Bordeaux, France"
    ],
    "start_date": "2005-04",
    "completion_date": "2008-01",
    "last_update": "2010-05-27",
    "topics": [
      "sauna-heat-therapy"
    ],
    "topic_names": [
      "Sauna & Heat Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00221728"
  },
  {
    "nct_id": "NCT01095549",
    "title": "Far Infrared Therapy on Peripheral Artery Disease in Hemodialysis Patients",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
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      "PHASE4"
    ],
    "enrollment": 300,
    "conditions": [
      "Peripheral Artery Disease"
    ],
    "interventions": [
      {
        "name": "WSTM TY101 FIR emitter (Far infrared therapy)",
        "type": "DEVICE"
      },
      {
        "name": "Placebo device",
        "type": "DEVICE"
      }
    ],
    "locations": [
      "Taipei Veterans General Hospital, Taipei, Taiwan, Taiwan",
      "Taipei Veterans General Hospital, Taipei, Taiwan, Taiwan"
    ],
    "start_date": "2010-03",
    "completion_date": "",
    "last_update": "2010-05-25",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT01095549"
  },
  {
    "nct_id": "NCT00860717",
    "title": "The Use of Low Level Laser Therapy for Wound Healing in Leprosy Patients",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 25,
    "conditions": [
      "Leprosy"
    ],
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      {
        "name": "Routine treatment",
        "type": "PROCEDURE"
      },
      {
        "name": "Low level laser therapy (LLLT)",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "Dr. Marcello Candia Reference Unit in Sanitary Dermatology of the State of Pará in Brazil (UREMC), Marituba, Pará, Brazil"
    ],
    "start_date": "2006-11",
    "completion_date": "2008-04",
    "last_update": "2009-12-12",
    "topics": [
      "photobiomodulation"
    ],
    "topic_names": [
      "Photobiomodulation / Red Light"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00860717"
  },
  {
    "nct_id": "NCT00883974",
    "title": "Sensitivity Training For Parents of Preterm Infants",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 45,
    "conditions": [
      "Development",
      "Preterm Birth"
    ],
    "interventions": [
      {
        "name": "Sensitivity Training",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Austin Health, Melbourne, Victoria, Australia",
      "Jeannette Milgrom, Melbourne, Victoria, Australia"
    ],
    "start_date": "2004-04",
    "completion_date": "2005-09",
    "last_update": "2009-10-28",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00883974"
  },
  {
    "nct_id": "NCT00996398",
    "title": "Cold Water Immersion Does Not Reduce Knee Joint Position Sense in Healthy Participants: a Randomised Cross-over Trial",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": 14,
    "conditions": [
      "Knee Joint Position Sense"
    ],
    "interventions": [
      {
        "name": "Tepid water immersion",
        "type": "OTHER"
      }
    ],
    "locations": [
      "University of Limerick, Limerick, Limerick, Ireland"
    ],
    "start_date": "2009-05",
    "completion_date": "2009-09",
    "last_update": "2009-10-15",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00996398"
  },
  {
    "nct_id": "NCT00674960",
    "title": "Far Infrared Irradiation for the Management, Control and Treatment of Frontotemporal Dementia",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 0,
    "conditions": [
      "Pick Disease of the Brain"
    ],
    "interventions": [
      {
        "name": "Radiation: Far Infrared Radiation (5μm to 20μm wavelength)",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2008-05",
    "completion_date": "2009-10",
    "last_update": "2009-08-14",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00674960"
  },
  {
    "nct_id": "NCT00674843",
    "title": "The Efficacy of Using Far Infrared Radiation to Manage Muscular Dystrophies",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 4,
    "conditions": [
      "Muscular Dystrophies"
    ],
    "interventions": [
      {
        "name": "Far Infrared Radiation",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2008-05",
    "completion_date": "2010-06",
    "last_update": "2009-08-14",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00674843"
  },
  {
    "nct_id": "NCT00673140",
    "title": "Far Infrared Irradiation for Control, Management and Treatment of Amyotrophic Lateral Sclerosis (ALS)",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 7,
    "conditions": [
      "Amyotrophic Lateral Sclerosis"
    ],
    "interventions": [
      {
        "name": "Far Infrared Radiation (5μm to 20μm wavelength)",
        "type": "RADIATION"
      },
      {
        "name": "Far infrared radiation",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2008-05",
    "completion_date": "2010-06",
    "last_update": "2009-08-14",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00673140"
  },
  {
    "nct_id": "NCT00599469",
    "title": "Far Infrared Treatment for Alzheimer's Disease",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 4,
    "conditions": [
      "Alzheimer Disease"
    ],
    "interventions": [
      {
        "name": "Far Infrared Radiation (5μm to 20μm wavelength)",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2008-02",
    "completion_date": "2009-04",
    "last_update": "2009-08-14",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00599469"
  },
  {
    "nct_id": "NCT00574522",
    "title": "Energy Specific Far Infrared Radiation Treatment for AIDS",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 3,
    "conditions": [
      "HIV Infections"
    ],
    "interventions": [
      {
        "name": "Far infrared",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2008-02",
    "completion_date": "2009-11",
    "last_update": "2009-08-14",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00574522"
  },
  {
    "nct_id": "NCT00574106",
    "title": "A Study to Evaluate the Effect of Far Infrared Radiation for Cancer Treatment",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 3,
    "conditions": [
      "Neoplasms"
    ],
    "interventions": [
      {
        "name": "Far Infrared Radiation",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2008-02",
    "completion_date": "2009-10",
    "last_update": "2009-08-14",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00574106"
  },
  {
    "nct_id": "NCT00574054",
    "title": "Far Infrared Radiation Treatment of Dementia and Other Mental Illness",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 4,
    "conditions": [
      "Dementia"
    ],
    "interventions": [
      {
        "name": "Far Infrared",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2008-02",
    "completion_date": "2009-03",
    "last_update": "2009-08-14",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00574054"
  },
  {
    "nct_id": "NCT00573820",
    "title": "Far Infrared Radiation Treatment for Prostate Cancer",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 4,
    "conditions": [
      "Prostatic Neoplasms"
    ],
    "interventions": [
      {
        "name": "Far Infrared Radiation",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2006-01",
    "completion_date": "2008-12",
    "last_update": "2009-08-14",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00573820"
  },
  {
    "nct_id": "NCT00573456",
    "title": "Far Infrared Radiation Treatment for Diabetes",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 2,
    "conditions": [
      "Diabetes Mellitus"
    ],
    "interventions": [
      {
        "name": "Far Infrared Radiation",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2006-05",
    "completion_date": "2009-04",
    "last_update": "2009-08-14",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00573456"
  },
  {
    "nct_id": "NCT00573209",
    "title": "Energy Specific Far Infrared Radiation Treatment for Erectile Dysfunction",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 3,
    "conditions": [
      "Erectile Dysfunction"
    ],
    "interventions": [
      {
        "name": "Far Infrared Radiation",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Mississauga, Ontario, Canada"
    ],
    "start_date": "2007-08",
    "completion_date": "2009-05",
    "last_update": "2009-08-14",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00573209"
  },
  {
    "nct_id": "NCT00573196",
    "title": "Far Infrared Radiation Treatment for Bipolar Condition",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 3,
    "conditions": [
      "Bipolar Disorder"
    ],
    "interventions": [
      {
        "name": "Far infrared",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Mississauga, Ontario, Canada"
    ],
    "start_date": "2006-09",
    "completion_date": "2008-06",
    "last_update": "2009-08-14",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00573196"
  },
  {
    "nct_id": "NCT00573573",
    "title": "Energy Specific Far Infrared Radiation Treatment for Hyperparathyroidism",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 2,
    "conditions": [
      "Hyperparathyroidism"
    ],
    "interventions": [
      {
        "name": "Far Infrared Radiation",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2007-01",
    "completion_date": "2009-07",
    "last_update": "2009-03-23",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00573573"
  },
  {
    "nct_id": "NCT00675155",
    "title": "Far Infrared Irradiation for Stroke Rehabilitation",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 10,
    "conditions": [
      "Stroke"
    ],
    "interventions": [
      {
        "name": "Far Infrared Radiation",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2008-05",
    "completion_date": "2010-06",
    "last_update": "2009-01-02",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00675155"
  },
  {
    "nct_id": "NCT00675077",
    "title": "Far Infrared Irradiation for Managing, Control and Treatment of Huntington's Disease (HD)",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 5,
    "conditions": [
      "Huntington Disease"
    ],
    "interventions": [
      {
        "name": "Far Infrared Radiation",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2008-05",
    "completion_date": "2010-06",
    "last_update": "2009-01-02",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00675077"
  },
  {
    "nct_id": "NCT00674934",
    "title": "Far Infrared Irradiation for Managing and Treating Multiple Sclerosis (MS)",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 5,
    "conditions": [
      "Multiple Sclerosis"
    ],
    "interventions": [
      {
        "name": "Far Infrared Radiation (5μm to 20μm wavelength)",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2008-05",
    "completion_date": "2010-06",
    "last_update": "2009-01-02",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00674934"
  },
  {
    "nct_id": "NCT00674895",
    "title": "Far Infrared Irradiation for Management and Treating of Parkinson's Disease (PD)",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 10,
    "conditions": [
      "Parkinson's Disease"
    ],
    "interventions": [
      {
        "name": "Far Infrared Radiation (5μm to 20μm wavelength)",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2008-05",
    "completion_date": "2010-06",
    "last_update": "2009-01-02",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00674895"
  },
  {
    "nct_id": "NCT00599482",
    "title": "Far Infrared Radiation for Sickle Cell Pain Management",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 10,
    "conditions": [
      "Anemia, Sickle Cell"
    ],
    "interventions": [
      {
        "name": "Far Infrared Radiation (5μm to 20μm wavelength)",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Mississauga, Ontario, Canada"
    ],
    "start_date": "2008-01",
    "completion_date": "2009-01",
    "last_update": "2009-01-02",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00599482"
  },
  {
    "nct_id": "NCT00599391",
    "title": "Far Infrared Treatment for Kidney Diseases",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 10,
    "conditions": [
      "Kidney Failure"
    ],
    "interventions": [
      {
        "name": "Far Infrared Radiation (5μm to 20μm wavelength)",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2008-02",
    "completion_date": "2009-02",
    "last_update": "2009-01-02",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00599391"
  },
  {
    "nct_id": "NCT00574418",
    "title": "Far Infrared Radiation Treatment for Uterine Fibroids",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 2,
    "conditions": [
      "Leiomyoma"
    ],
    "interventions": [
      {
        "name": "Far Infrared Radiation (5μm to 20μm wavelength)",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2006-01",
    "completion_date": "2008-09",
    "last_update": "2009-01-02",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00574418"
  },
  {
    "nct_id": "NCT00573807",
    "title": "Energy Specific Far Infrared Radiation Treatment for Sciatica",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 2,
    "conditions": [
      "Sciatica"
    ],
    "interventions": [
      {
        "name": "Far Infrared Radiation (5μm to 20μm wavelength)",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2006-01",
    "completion_date": "2008-12",
    "last_update": "2009-01-02",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00573807"
  },
  {
    "nct_id": "NCT00573352",
    "title": "Far Infrared Radiation Treatment for Osteoarthritis",
    "status": "UNKNOWN",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE1"
    ],
    "enrollment": 2,
    "conditions": [
      "Osteoarthritis"
    ],
    "interventions": [
      {
        "name": "Far Infrared",
        "type": "RADIATION"
      }
    ],
    "locations": [
      "The Centre for Incurable Diseases, Toronto, Ontario, Canada"
    ],
    "start_date": "2006-09",
    "completion_date": "2008-12",
    "last_update": "2009-01-02",
    "topics": [
      "infrared-sauna"
    ],
    "topic_names": [
      "Infrared Sauna"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00573352"
  },
  {
    "nct_id": "NCT00722514",
    "title": "Evaluation of a Patient Education Program for Ankylosing Spondylitis",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "NA"
    ],
    "enrollment": "",
    "conditions": [
      "Ankylosing Spondylitis",
      "Spondyloarthritis"
    ],
    "interventions": [
      {
        "name": "patient education",
        "type": "BEHAVIORAL"
      },
      {
        "name": "Standard Care",
        "type": "BEHAVIORAL"
      }
    ],
    "locations": [
      "Rehazentrum Bad Eilsen, Bad Eilsen, Lower Saxony, Germany"
    ],
    "start_date": "1998-07",
    "completion_date": "2001-07",
    "last_update": "2008-08-14",
    "topics": [
      "massage-therapy"
    ],
    "topic_names": [
      "Massage Therapy"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00722514"
  },
  {
    "nct_id": "NCT00313547",
    "title": "High-Dose Quinapril Versus Low-Dose Quinapril Plus Amlodipine in the Treatment of High-Risk Hypertensive Patients",
    "status": "TERMINATED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE4"
    ],
    "enrollment": 40,
    "conditions": [
      "Hypertension"
    ],
    "interventions": [
      {
        "name": "Quinapril 40 mg",
        "type": "DRUG"
      },
      {
        "name": "Quinapril 10 mg and amlodipine 5 mg",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Montreal Heart Institute, Montreal, Quebec, Canada"
    ],
    "start_date": "2006-04",
    "completion_date": "2008-03",
    "last_update": "2008-05-02",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00313547"
  },
  {
    "nct_id": "NCT00378521",
    "title": "Dose Response Study of a Topical Gel for the Treatment of Raynaud's Phenomenon",
    "status": "COMPLETED",
    "study_type": "INTERVENTIONAL",
    "phases": [
      "PHASE2"
    ],
    "enrollment": 15,
    "conditions": [
      "Raynaud's Disease",
      "Raynaud's Disease Secondary to Scleroderma",
      "Raynaud's Disease Secondary to Autoimmune Disease"
    ],
    "interventions": [
      {
        "name": "MQX-503",
        "type": "DRUG"
      }
    ],
    "locations": [
      "Rainier Clinical Research, Renton, Washington, United States"
    ],
    "start_date": "2006-07",
    "completion_date": "2006-07",
    "last_update": "2007-05-29",
    "topics": [
      "cold-water-immersion"
    ],
    "topic_names": [
      "Cold-Water Immersion"
    ],
    "url": "https://clinicaltrials.gov/study/NCT00378521"
  }
]
