Folate receptor-specific antitumor activity of EC131, a folate-maytansinoid conjugate.

Joseph A Reddy, Elaine Westrick, Hari K R Santhapuram, Stephen J Howard, Michael L Miller, Marilynn Vetzel, Iontcho Vlahov, Ravi V J Chari, Victor S Goldmacher, Christopher P Leamon

Cancer research

2007

Journal Article

Animals, Antineoplastic Agents, Carrier Proteins, Cell Line, Tumor, Drug Screening Assays, Antitumor, Folate Receptors, GPI-Anchored, Folic Acid, Humans, KB Cells, Maximum Tolerated Dose, Maytansine, Maytenus, Mice, Mice, Inbred BALB C, Mice, Nude, Neoplasm Transplantation, Plant Extracts, Receptors, Cell Surface