Activation of glycine receptors in the lateral habenula rescues anxiety- and depression-like behaviors associated with alcohol withdrawal and reduces alcohol intake in rats.

Wenting Li, Wanhong Zuo, Wei Wu, Qi Kang Zuo, Rao Fu, Liangzhi Wu, Haifeng Zhang, Michael Ndukwe, Jiang-Hong Ye

Neuropharmacology

2019

Journal Article, Research Support, N.I.H., Extramural

Action Potentials, Alcohol Drinking, Animals, Anxiety, Behavior, Animal, Depression, Glycine, Habenula, Inhibitory Postsynaptic Potentials, Male, Microinjections, Neural Inhibition, Neurons, Rats, Receptors, Glycine, Sarcosine, Strychnine, Substance Withdrawal Syndrome