Effects of local heat on metabolic health, frailty risk, and exercise adaptations in pre-diabetic older adults: Protocol for the Heat and Exercise in Aging as Therapy (HEAT) clinical trial.

Hui-Ying Luk, Casey R Appell, Fangyuan Zhang, Jarrod Blinch, K Sreekumaran Nair, Chwan-Li Shen, Danielle E Levitt

PloS one

2026

Clinical Trial Protocol, Journal Article

Aged, Female, Humans, Male, Adaptation, Physiological, Aging, Blood Glucose, Diabetes Mellitus, Type 2, Exercise, Frailty, High-Intensity Interval Training, Hot Temperature, Muscle, Skeletal, Prediabetic State, Randomized Controlled Trials as Topic