Curcumin alleviates cold stress-induced myocardial injury by regulating macrophage polarization through the STUB1/STAT1-STAT6-KLF4 signaling axis.

Peifang Cong, Changci Tong, Jinpeng Liu, Zhonghua Luo, Haikun Li, Jian Yao, Yunen Liu

International immunopharmacology

2026

Journal Article

Animals, Kruppel-Like Factor 4, STAT1 Transcription Factor, Macrophages, Curcumin, Signal Transduction, STAT6 Transcription Factor, Kruppel-Like Transcription Factors, Mice, Ubiquitin-Protein Ligases, Mice, Inbred C57BL, Male, Cold-Shock Response, Humans, Macrophage Activation