A cold-induced GDF15-secreting adipocyte subpopulation regulates energy homeostasis through endocrine signaling.

Chunyan Wu, Tongtong Wang, Songlin Gong, Jing Zhang, Charlotte G Mann, Min Li, Ziyu Liu, Yizhi Sun, Shenwei Shi, Zhenghong Liu, Katrien De Bock, Miroslav Balaz

Cell reports

2026

Journal Article

Animals, Energy Metabolism, Uncoupling Protein 1, Cold Temperature, Signal Transduction, Homeostasis, Growth Differentiation Factor 15, Mice, Knockout, Mice, Adipocytes, Brown, Humans, Adipose Tissue, Brown, Thermogenesis, Adipocytes