Single-session extraoral photobiomodulation reduces early postoperative pain but not edema or trismus after impacted mandibular third molar extraction: a randomized controlled trial.
Lasers in medical science · PMID 42747615
Photobiomodulation has been tested for pain across several conditions, with some trials and reviews reporting benefit. Results vary by diagnosis, wavelength, energy dose, treatment site, schedule and comparator. A positive result for one condition and protocol does not establish that any red-light device relieves pain generally.
Dose reporting and condition-specific effects make broad conclusions unreliable.
Included: Records in the Photobiomodulation / low-level light topic whose high-signal metadata contains at least one outcome term below.
Outcome expression: "pain" OR "analges" OR "soreness"
Excluded: Records outside the intervention topic, animal-only records rejected by the source query, and records without an outcome-term match. This is a reproducible index, not a systematic review.
Download receipt JSONEach record matched the intervention topic and at least one claim-specific outcome term. Open a record for source metadata and inclusion provenance.
Lasers in medical science · PMID 42747615
Lasers in medical science · PMID 42742785
Lasers in medical science · PMID 42734675
Lasers in medical science · PMID 42733098
PloS one · PMID 42678980
Lasers in medical science · PMID 42631884
Revista gaucha de enfermagem · PMID 42615775
Photobiomodulation, photomedicine, and laser surgery · PMID 42581717
BMJ open · PMID 42552011
Lasers in medical science · PMID 42507053
Lasers in medical science · PMID 42501075
BMC oral health · PMID 42458386
Registration is not a result. Status and dates come from ClinicalTrials.gov.
NCT07826130 · Enrollment: 45
NCT07750912 · Enrollment: 15
NCT07671612 · Enrollment: 300
NCT07790016 · Enrollment: 12
NCT06040190 · Enrollment: 50
NCT06194136 · Enrollment: not listed
NCT05255731 · Enrollment: 80
NCT04003545 · Enrollment: 76
Health Research Database. “Does red-light therapy reduce pain?” HRD Claim Ledger. Dataset 2026-09-18. Accessed 2026-09-18.
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